HCPCS code Q5129: Vegzelma injection, per 10 mg2026 Medicare rate & RVUs in Texas

Reports bevacizumab-adcd (Vegzelma), a bevacizumab biosimilar administered by intravenous infusion for cancer treatment, in 10 mg billing units.

CMS RVU26DEffective Oct 1, 20268 payment localities

CMS doesn’t publish an office rate for Q5129 in Texas.

—Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Texas
  2. What Q5129 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q5129 covers

Q5129 identifies bevacizumab-adcd, marketed as Vegzelma, a biosimilar of bevacizumab. Oncology practices typically report it for the drug administered by intravenous infusion as part of a cancer treatment regimen. Bevacizumab is used for several cancers, with the treatment combination depending on the cancer and regimen. The code identifies the specific biosimilar supplied, rather than bevacizumab products with different biosimilar names.

CMS assigns this code physician fee schedule status E, excluding it from the physician fee schedule. When Medicare covers the drug, it is treated as a Part B drug and generally priced using CMS’s quarterly Average Sales Price drug files; coverage is left to the Medicare contractor’s judgment. Each billing unit represents 10 mg of bevacizumab-adcd, so the reported units reflect the administered amount in 10 mg increments. The drug code identifies the medication; the infusion service is a separate service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q5129 pays more and less in Texas

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

8 of 8 payment localities

Q5129 office and facility rates by payment locality
Payment localityOfficeFacility
Austin, TXUnavailableUnavailable
Beaumont, TXUnavailableUnavailable
Brazoria, TXUnavailableUnavailable
Dallas, TXUnavailableUnavailable
Fort Worth, TXUnavailableUnavailable
Galveston, TXUnavailableUnavailable
Houston, TXUnavailableUnavailable
Rest of TexasUnavailableUnavailable

How the Q5129 rate is calculated

Each of Q5129’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q5129

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q5129

Q5129 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · Q5129

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

Q5129 isn’t priced in this setting.

Q5129 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • Q5129

    Vegzelma injection, per 10 mg0 wRVU

    Not priced

  • Q5118

    Zirabev injection, per 10 mg0 wRVU

    Not priced

  • Q5126

    Alymsys injection, per 10 mg0 wRVU

    Not priced

  • J9035

    Bevacizumab, per 10 mg0 wRVU

    Not priced

How to choose

Q5118Zirabev injectionPer 10 mg
Q5118 identifies Zirabev, another bevacizumab biosimilar. Q5129 identifies Vegzelma; the product actually administered determines which code applies.
Q5126Alymsys injectionPer 10 mg
Q5126 identifies Alymsys, a different bevacizumab biosimilar. Use Q5129 for Vegzelma, not simply because both products contain a bevacizumab biosimilar.
J9035BevacizumabPer 10 mg
J9035 identifies bevacizumab, while Q5129 identifies the bevacizumab-adcd biosimilar Vegzelma. Choose based on the specific drug product administered.

Q5129 billing questions

When should a biller use Q5129 rather than another bevacizumab code?

Use Q5129 when the product administered is bevacizumab-adcd (Vegzelma). Select the code for the specific bevacizumab product supplied, rather than choosing by drug class alone.

How many units does Q5129 represent?

One unit represents 10 mg of bevacizumab-adcd. Report units based on the amount administered in 10 mg increments.

Does Q5129 include the infusion administration?

No. Q5129 identifies the drug. The infusion service is a separate service.

How does Medicare treat Q5129?

CMS excludes it from the physician fee schedule with status E. When covered, it is a Part B drug generally priced through CMS quarterly ASP drug files, and coverage is determined by the Medicare contractor.

Is Medicare coverage automatic for Vegzelma?

No. CMS leaves coverage for Q5129 to the Medicare contractor’s judgment.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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