CPT 43198: Esophageal biopsyMedicare rate & RVUs

Reports flexible transnasal esophagoscopy with biopsy when a physician samples esophageal tissue to evaluate suspected mucosal disease or an abnormality.

CMS RVU26DEffective Oct 1, 2026109 payment localities198 Medicare services in 2024

Medicare pays $218.11 for 43198 nationally in the office and $81.83 in a hospital or facility. Local office rates run $192.82–$287.32.

Medicare rate · 43198

Esophageal biopsy

Swap in your local Medicare rate.

Work RVUs
1.77
Total RVUs
6.53
Global days
000

National rate · 2026

$218.11

Office setting, before claim adjustments.

See every locality for 43198 →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What 43198 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 43198 covers

The physician advances a flexible endoscope through the nose into the esophagus and obtains tissue samples for examination. Otolaryngologists and other physicians trained in transnasal esophagoscopy may perform this service in an office or facility setting. It can be used to investigate symptoms such as dysphagia or to assess a visible or suspected esophageal abnormality when tissue diagnosis is needed.

Report 43198 for the transnasal flexible approach when biopsy is performed; the code includes single or multiple biopsies during the session. The procedure note should establish the route, esophageal findings, biopsy sites, and that tissue was obtained. CMS assigns a 0-day global period, so same-day preoperative and postoperative care is included. When related endoscopies are performed together, endoscopy family pricing applies. Modifier 50 is inappropriate for this service. Medicare does not pay an assistant at surgery for it, and co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 43198 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$192.82 to $287.32

$192.82$240.07$287.32
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

43198 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$195.65$76.41
Alaska*$253.71$108.58
Arizona$212.24$80.18
Arkansas$192.82$75.76
Atlanta$222.37$83.92
Austin$226.01$81.83
Bakersfield$230.43$81.07
Baltimore/Surr. Cntys$232.03$85.81
Beaumont$203.96$79.95
Brazoria$215.39$80.34

43198 rates by state

Office rate range in each state. Select a state to see its payment localities.

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Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$192.82

$258.51

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
43198 office rate range by state
State / territoryOffice rate rangeLocalities
AK$253.711
AL$195.651
AR$192.821
AZ$212.241
CA$229.70–$287.3229
CO$226.631
CT$232.641
DC$249.061
DE$215.751
FL$215.68–$237.053
GA$203.44–$222.372
GU$235.231
HI$235.231
IA$200.271
ID$201.661
IL$209.70–$230.094
IN$202.821
KS$199.501
KY$200.681
LA$200.43–$210.362
MA$225.34–$248.842
MD$219.82–$249.063
ME$202.90–$213.672
MI$206.08–$218.562
MN$216.601
MO$197.10–$210.893
MS$194.991
MT$218.091
NC$205.001
ND$213.151
NE$201.311
NH$223.241
NJ$235.14–$246.502
NM$207.281
NV$216.861
NY$208.10–$257.525
OH$205.071
OK$200.131
OR$215.03–$233.642
PA$205.30–$226.962
PR$219.641
RI$223.301
SC$205.411
SD$212.561
TN$200.531
TX$203.96–$226.018
UT$208.221
VA$213.09–$249.062
VI$219.641
VT$212.481
WA$224.86–$253.732
WI$206.001
WV$201.971
WY$215.941

How the 43198 rate is calculated

Each of 43198’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 43198

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.77Practice expense 4.51Malpractice 0.25

6.5300 adjusted RVUs×$33.4009 conversion factor=$218.11

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 43198

The CMS indicators that decide how 43198 is paid alongside other services.

CMS payment indicators · 43198

Esophageal biopsy

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures3Endoscopy family rules apply.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

43198 without 51 · national office

$218.11

Esophageal biopsy

43198-51 · Second procedure: 50%

$109.06

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

43198 compared with similar codes

Compare codes

43198 vs 43197 vs 43193 vs 43202: national Medicare rates

Swap in your local Medicare rate.

  • 43198
    Esophageal biopsy · 1.77 wRVU
    $218.11
  • 43197
    Esophagoscopy · 1.48 wRVU
    $197.07−$21.04
  • 43193
    Esophagoscopy · 2.72 wRVU
    —
  • 43202
    Esophageal biopsy · 1.68 wRVU
    $393.13+$175.02

How to choose

43197Esophagoscopy
Choose 43198 when tissue is obtained by biopsy during flexible transnasal esophagoscopy. Choose 43197 for the transnasal diagnostic examination with brushing or washing collection.
43193Esophagoscopy
Both involve esophageal biopsy, but 43193 uses a rigid instrument passed transorally; 43198 uses a flexible instrument passed transnasally.
43202Esophageal biopsy
Both report flexible esophagoscopy with biopsy. Use 43198 for the transnasal route and 43202 for the transoral route.

43198 billing questions

How does 43198 differ from 43197?

43198 reports tissue biopsy during flexible transnasal esophagoscopy. 43197 is the transnasal flexible diagnostic service with specimen collection by brushing or washing.

Can multiple biopsy samples be billed as multiple units?

No. The code covers a single or multiple biopsies during the procedure; document the sampled sites and findings, but do not count each specimen as a separate unit of 43198.

How does 43198 differ from 43202?

Both include esophageal biopsy, but 43198 uses a transnasal approach and 43202 uses a transoral flexible approach. The documented route identifies the appropriate code.

Should modifier 50 be reported?

No. The CMS bilateral adjustment does not apply, and modifier 50 is inappropriate for this esophageal procedure.

What happens when another related endoscopy is performed at the same session?

CMS endoscopy family pricing applies when related endoscopies are performed together. The procedure record should identify each service performed.

Is an assistant or co-surgeon payable?

Medicare does not pay an assistant at surgery for 43198. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 43198PPRRVU2026_Oct_nonQPP.csv, line 5,139 (RVU26D)

Open CMS sourceHow we calculate rates

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