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CMS RVU26D · Effective 2026-10-01

65450 Corneal treatment Medicare reimbursement rates

An ophthalmologist destroys a focal corneal lesion with a selected treatment method rather than excising it or taking tissue for diagnosis. Compare 65450 office and facility rates across CMS payment localities.

Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.

What does Medicare pay for 65450?

The service location and office or facility setting determine which base rate applies. These are the supported base rates for the 109 payment areas shown below, using the same CMS release.

Office / nonfacility

$300.42–$437.26

109 of 109 localities have a supported rate.

Lowest: Arkansas

Highest: San Jose-Sunnyvale-Santa Clara (San Benito Cnty)

A spread of $136.84 per service.

Facility setting

$261.11–$371.27

109 of 109 localities have a supported rate.

Lowest: Arkansas

Highest: San Jose-Sunnyvale-Santa Clara (San Benito Cnty)

A spread of $110.16 per service.

These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.

Find 65450 in your payment locality →

Where 65450 pays more and less

109 payment localities

$300.42 to $437.26

$300.42$368.84$437.26
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

Ophthalmology

About 65450: Corneal lesion destruction treatment

An ophthalmologist destroys a focal corneal lesion with a selected treatment method rather than excising it or taking tissue for diagnosis.

This ophthalmic procedure treats a focal lesion on the cornea by destroying the target with a selected method, such as freezing, light-based coagulation, or heat cautery. It is generally performed by an ophthalmologist, often a cornea specialist, in an office procedure room or ambulatory surgical setting. It differs from cutting out corneal tissue, sampling it for diagnosis, or removing a broader area of surface epithelium.

Report the service for the treated eye and document the lesion’s location, the treatment method, and the work performed. Medicare assigns a 90-day global period, including the day-before preoperative visit and 90 days of related postoperative care. When multiple procedures are performed in one session, the highest-valued procedure is paid in full and the others at 50%. For bilateral treatment, modifier 50 is paid at 150%. Medicare does not pay an assistant at surgery; co-surgeons and team surgery are not permitted.

CMS billing rules for 65450

Global period
Major surgery with a 90-day global period: the day-before preoperative visit and 90 days of related postoperative care are included.
Multiple procedures
Standard multiple procedure reduction: the highest-valued procedure is paid in full and others at 50% when performed in the same session.
Bilateral procedures
Bilateral procedure with modifier 50 is paid at 150%.
Assistant at surgery
Statutory restriction: assistant at surgery is not paid.
Co-surgeons
Co-surgeons not permitted.
Team surgery
Team surgery not permitted.

Where the value comes from

  • Work RVU3.38 · 34%
  • Practice expense (office) RVU6.38 · 64%
  • Malpractice RVU0.26 · 3%

549

Medicare services in 2024 · #3471 by national volume

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

65450 compared with similar codes

Office rate ranges across all CMS payment localities, from the same CMS release.

65400

Corneal excision

Superficial lesion, not pterygium

$627.47–$907.89

Choose 65400 when the lesion is cut out. Choose 65450 when the documented treatment destroys the lesion in place.

65410

Corneal biopsy

Tissue sampling

$129.13–$188.40

65410 is for obtaining a corneal tissue sample for diagnosis; 65450 treats a lesion rather than sampling it.

65435

Corneal treatment

Epithelial removal

$75.16–$108.31

65435 involves removal of corneal epithelium. 65450 targets a focal lesion for destruction.

65436

Corneal treatment

Chemical treatment for recurrent erosion

$354.61–$501.83

65436 is used for corneal surface treatment with a chelating agent. 65450 describes focal lesion destruction by another treatment method.

See how rates vary across the country

65450 · Office / nonfacility · Non-QP. Choose a state to explore its payment localities. A range means the amount varies within that state.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$300.42

$401.08

Color shows the midpoint of each state’s locality range.

View all state and territory rates as a table
State / territoryRate rangeLocalities
AK$401.081
AL$304.271
AR$300.421
AZ$326.821
CA$353.02–$437.2629
CO$347.771
CT$355.171
DC$379.691
DE$331.811
FL$329.67–$356.693
GA$313.33–$340.172
GU$360.221
HI$360.221
IA$311.331
ID$313.051
IL$321.03–$347.934
IN$314.661
KS$309.911
KY$310.291
LA$309.81–$323.292
MA$346.01–$379.692
MD$337.65–$379.693
ME$314.35–$329.552
MI$317.26–$333.182
MN$334.741
MO$305.04–$324.473
MS$302.791
MT$334.661
NC$317.261
ND$329.521
NE$312.871
NH$342.331
NJ$359.64–$376.482
NM$318.741
NV$333.441
NY$321.44–$389.625
OH$316.211
OK$309.941
OR$331.25–$357.912
PA$316.73–$347.122
PR$336.891
RI$342.921
SC$317.181
SD$328.911
TN$311.261
TX$314.88–$346.278
UT$321.011
VA$328.50–$379.692
VI$336.891
VT$328.261
WA$345.36–$387.112
WI$319.721
WV$310.501
WY$332.421

Compare 65450 by payment locality

Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.

109 of 109 payment localities

65450 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama

Office

$304.27

Facility

$264.23
Alaska*

Office

$401.08

Facility

$352.34
Arizona

Office

$326.82

Facility

$282.48
Arkansas

Office

$300.42

Facility

$261.11
Atlanta

Office

$340.17

Facility

$293.68
Austin

Office

$346.27

Facility

$297.86
Bakersfield

Office

$353.88

Facility

$303.73
Baltimore/Surr. Cntys

Office

$354.10

Facility

$305.00
Beaumont

Office

$314.88

Facility

$273.24
Brazoria

Office

$331.75

Facility

$286.40
Chicago

Office

$347.78

Facility

$301.79
Chico

Office

$353.02

Facility

$302.87
Colorado

Office

$347.77

Facility

$299.08
Connecticut

Office

$355.17

Facility

$305.88
Dallas

Office

$333.61

Facility

$288.03
Dc + Md/Va Suburbs

Office

$379.69

Facility

$325.78
Delaware

Office

$331.81

Facility

$286.60
Detroit

Office

$333.18

Facility

$289.02
East St. Louis

Office

$326.44

Facility

$284.34
El Centro

Office

$353.07

Facility

$302.92
Fort Lauderdale

Office

$344.46

Facility

$298.11
Fort Worth

Office

$331.59

Facility

$286.47
Fresno

Office

$353.02

Facility

$302.87
Galveston

Office

$332.59

Facility

$287.16
Hanford-Corcoran

Office

$353.02

Facility

$302.87
Hawaii, Guam

Office

$360.22

Facility

$308.19
Houston

Office

$337.35

Facility

$291.91
Idaho

Office

$313.05

Facility

$270.95
Indiana

Office

$314.66

Facility

$272.24
Iowa

Office

$311.33

Facility

$269.46
Kansas

Office

$309.91

Facility

$268.55
Kentucky

Office

$310.29

Facility

$269.61
Los Angeles-Long Beach-Anaheim (Los Angeles/Orange Cnty)

Office

$375.38

Facility

$321.25
Madera

Office

$353.02

Facility

$302.87
Manhattan

Office

$381.51

Facility

$328.34
Merced

Office

$353.02

Facility

$302.87
Metropolitan Boston

Office

$379.69

Facility

$325.05
Metropolitan Kansas City

Office

$321.48

Facility

$278.51
Metropolitan Philadelphia

Office

$347.12

Facility

$299.49
Metropolitan St. Louis

Office

$324.47

Facility

$280.90
Miami

Office

$356.69

Facility

$309.06
Minnesota

Office

$334.74

Facility

$287.66
Mississippi

Office

$302.79

Facility

$263.39
Modesto

Office

$353.02

Facility

$302.87
Montana**

Office

$334.66

Facility

$288.90
Napa

Office

$405.28

Facility

$344.97
Nebraska

Office

$312.87

Facility

$270.63
Nevada**

Office

$333.44

Facility

$287.63
New Hampshire

Office

$342.33

Facility

$294.69
New Mexico

Office

$318.74

Facility

$276.77
New Orleans

Office

$323.29

Facility

$280.23
North Carolina

Office

$317.26

Facility

$274.57
North Dakota**

Office

$329.52

Facility

$283.76
Northern Nj

Office

$376.48

Facility

$323.39
Nyc Suburbs/Long Island

Office

$389.62

Facility

$335.21
Ohio

Office

$316.21

Facility

$274.43
Oklahoma

Office

$309.94

Facility

$269.08
Oxnard-Thousand Oaks-Ventura

Office

$373.35

Facility

$319.26
Portland

Office

$357.91

Facility

$307.08
Poughkpsie/N Nyc Suburbs

Office

$361.83

Facility

$311.72
Puerto Rico

Office

$336.89

Facility

$290.63
Queens

Office

$384.52

Facility

$330.44
Redding

Office

$353.02

Facility

$302.87
Rest Of California

Office

$353.02

Facility

$302.87
Rest Of Florida

Office

$329.67

Facility

$285.92
Rest Of Georgia

Office

$313.33

Facility

$272.51
Rest Of Illinois

Office

$321.03

Facility

$279.25
Rest Of Louisiana

Office

$309.81

Facility

$269.31
Rest Of Maine

Office

$314.35

Facility

$272.25
Rest Of Maryland

Office

$337.65

Facility

$291.34
Rest Of Massachusetts

Office

$346.01

Facility

$297.83
Rest Of Michigan

Office

$317.26

Facility

$275.48
Rest Of Missouri

Office

$305.04

Facility

$265.60
Rest Of New Jersey

Office

$359.64

Facility

$309.67
Rest Of New York

Office

$321.44

Facility

$277.97
Rest Of Oregon

Office

$331.25

Facility

$285.67
Rest Of Pennsylvania

Office

$316.73

Facility

$274.72
Rest Of Texas

Office

$322.97

Facility

$279.54
Rest Of Washington

Office

$345.36

Facility

$297.18
Rhode Island

Office

$342.92

Facility

$295.65
Riverside-San Bernardino-Ontario

Office

$355.89

Facility

$305.74
Sacramento-Roseville-Folsom

Office

$369.45

Facility

$316.23
Salinas

Office

$368.03

Facility

$314.99
San Diego-Chula Vista-Carlsbad

Office

$375.85

Facility

$321.13
San Francisco-Oakland-Berkeley (Marin Cnty)

Office

$428.07

Facility

$363.55
San Francisco-Oakland-Berkeley (San Francisco/San Mateo/Alameda/Contra Costa Cnty)

Office

$427.78

Facility

$363.26
San Jose-Sunnyvale-Santa Clara (San Benito Cnty)

Office

$437.26

Facility

$371.27
San Jose-Sunnyvale-Santa Clara (Santa Clara Cnty)

Office

$436.05

Facility

$370.06
San Luis Obispo-Paso Robles

Office

$362.19

Facility

$310.07
Santa Cruz-Watsonville

Office

$378.83

Facility

$323.24
Santa Maria-Santa Barbara

Office

$369.18

Facility

$315.83
Santa Rosa-Petaluma

Office

$382.62

Facility

$326.43
Seattle (King Cnty)

Office

$387.11

Facility

$330.96
South Carolina

Office

$317.18

Facility

$274.90
South Dakota**

Office

$328.91

Facility

$283.15
Southern Maine

Office

$329.55

Facility

$284.21
Stockton

Office

$353.02

Facility

$302.87
Suburban Chicago

Office

$347.93

Facility

$300.93
Tennessee

Office

$311.26

Facility

$269.67
Utah

Office

$321.01

Facility

$277.99
Vallejo

Office

$404.86

Facility

$344.55
Vermont

Office

$328.26

Facility

$282.95
Virgin Islands

Office

$336.89

Facility

$290.63
Virginia

Office

$328.50

Facility

$283.52
Visalia

Office

$353.02

Facility

$302.87
West Virginia

Office

$310.50

Facility

$270.74
Wisconsin

Office

$319.72

Facility

$275.88
Wyoming**

Office

$332.42

Facility

$286.66
Yuba City

Office

$353.02

Facility

$302.87

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65450 billing questions

How is 65450 different from corneal lesion excision?

65450 is for destroying the lesion in place. Use 65400 when the corneal lesion is removed by excision.

Can a corneal biopsy be reported as 65450?

No. A biopsy obtains tissue for diagnostic examination; 65450 treats a lesion by destruction.

How does 65450 differ from corneal epithelial removal?

65435 describes removal of corneal epithelium, with or without chemical cautery. Use 65450 when the documented service is focal lesion destruction.

How is bilateral treatment reported?

Report modifier 50 when both eyes are treated. CMS pays the bilateral procedure at 150%.

What postoperative care is included?

The 90-day global period includes the day-before preoperative visit and 90 days of related postoperative care.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.

Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.

RVUs for 65450PPRRVU2026_Oct_nonQPP.csv, line 7,325 (RVU26D)