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CMS RVU26D · Effective 2026-10-01

88341 in Chico

Office / nonfacility

$101.59

Base rate per service

Facility setting

Not available in this setting

Base rate per service

Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.

Surgical pathology

About 88341: Additional single-antibody immunostain per specimen

Report 88341 for each additional distinct single-antibody immunostain on a specimen after its initial single-antibody stain is reported with 88342.

This service covers another single-antibody immunohistochemistry or immunocytochemistry stain on a specimen after its first single-antibody stain. A laboratory applies a distinct antibody, such as a keratin or CD marker, to tissue sections or cytology material. A pathologist interprets the staining to help classify a carcinoma, lymphoma, or other lesion. Hospital pathology departments and independent laboratories perform the staining; the specimen may also have a separately reported surgical pathology examination.

Report one unit for each distinct additional single-antibody stain per specimen, not for each slide or tissue block. Report the initial single-antibody stain on each separately identified specimen with 88342; document the specimen, antibodies tested, and results. Control slides do not generate additional units. As an add-on, 88341 must accompany a primary procedure and is paid within that procedure’s global period. Modifier 26 identifies the pathologist’s interpretation, and modifier TC identifies the laboratory’s staining, reagents, and staff work when components are billed separately. Billing without either modifier identifies the global service.

CMS billing rules for 88341

Global period
Add-on code: billed only together with a primary procedure and paid within that procedure's global period.
Professional and technical components
Diagnostic test with a professional component (modifier 26, interpretation) and a technical component (modifier TC, equipment and staff); billing without a modifier is the global service.

Where the value comes from

  • Work RVU0.55 · 20%
  • Practice expense (office) RVU2.26 · 80%
  • Malpractice RVU0.01 · 0%

3.8M

Medicare services in 2024 · #49 by national volume

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

88341 compared with similar codes

Office rates for Chico, from the same CMS release.

88342

Antibody stain

First single antibody per specimen

$118.64

88342 reports the initial single-antibody stain on a specimen. 88341 reports each additional distinct single-antibody stain on that specimen and is an add-on code.

88344

Immunostain

Multiplex antibody procedure

$187.64

88344 reports a multiplex procedure producing distinguishable results from multiple antibodies. Report 88341 for an additional separate single-antibody stain.

88360

Tumor IHC scoring

Manual quantitative, per antibody

$129.22

88360 reports manual morphometric analysis of a tumor immunostain. Do not also report 88341 for that antibody on the same specimen.

88350

Immunofluorescence

Each additional antibody stain

$115.24

88350 reports an additional immunofluorescence antibody stain, such as in direct immunofluorescence of renal or skin tissue. 88341 reports an additional immunohistochemistry or immunocytochemistry single-antibody stain.

The same code, a different location

How does Chico compare?

In Bakersfield, the office rate for 88341 is $101.66—$0.07 higher than the $101.59 rate in Chico. Both use the same code, release and participation basis.

88341 across payment areas

Same release and payment basis · bars start at $0

  1. Chico · This locality

    $101.59

  2. Bakersfield

    $101.66

    $0.07 higher than Chico

  3. El Centro

    $101.60

    $0.01 higher than Chico

  4. Fresno

    $101.59

    The same base rate than Chico

  5. Hanford-Corcoran

    $101.59

    The same base rate than Chico

  6. Los Angeles-Long Beach-Anaheim (Los Angeles/Orange Cnty)

    $108.65

    $7.06 higher than Chico

  7. Madera

    $101.59

    The same base rate than Chico

Other payment areas listed in California appear first, followed by selected cross-country examples. The chart compares amounts, not distance.

Across 109 of 109 CMS payment localities with a supported office rate, 88341 ranges from $83.39 in Arkansas to $129.42 in San Jose-Sunnyvale-Santa Clara (San Benito Cnty). This is a geographic range, not an average.

The code’s RVUs stay the same in these comparisons. Geographic adjustments to work, practice expense and malpractice change the dollar amount. A city name alone may not identify the payment area for a service address.

Compare all 108 other payment areas

  • Merced

    California · 88341

    Office

    $101.59

    Facility

    Unavailable

    The same base rate than Chico for the office setting.

  • Modesto

    California · 88341

    Office

    $101.59

    Facility

    Unavailable

    The same base rate than Chico for the office setting.

  • Napa

    California · 88341

    Office

    $119.19

    Facility

    Unavailable

    $17.60 higher than Chico for the office setting.

  • Oxnard-Thousand Oaks-Ventura

    California · 88341

    Office

    $108.32

    Facility

    Unavailable

    $6.73 higher than Chico for the office setting.

  • Redding

    California · 88341

    Office

    $101.59

    Facility

    Unavailable

    The same base rate than Chico for the office setting.

  • Rest Of California

    California · 88341

    Office

    $101.59

    Facility

    Unavailable

    The same base rate than Chico for the office setting.

  • Riverside-San Bernardino-Ontario

    California · 88341

    Office

    $101.72

    Facility

    Unavailable

    $0.13 higher than Chico for the office setting.

  • Sacramento-Roseville-Folsom

    California · 88341

    Office

    $107.00

    Facility

    Unavailable

    $5.41 higher than Chico for the office setting.

  • Salinas

    California · 88341

    Office

    $106.61

    Facility

    Unavailable

    $5.02 higher than Chico for the office setting.

  • San Diego-Chula Vista-Carlsbad

    California · 88341

    Office

    $109.38

    Facility

    Unavailable

    $7.79 higher than Chico for the office setting.

  • San Francisco-Oakland-Berkeley (Marin Cnty)

    California · 88341

    Office

    $126.70

    Facility

    Unavailable

    $25.11 higher than Chico for the office setting.

  • San Francisco-Oakland-Berkeley (San Francisco/San Mateo/Alameda/Contra Costa Cnty)

    California · 88341

    Office

    $126.69

    Facility

    Unavailable

    $25.10 higher than Chico for the office setting.

  • San Jose-Sunnyvale-Santa Clara (San Benito Cnty)

    California · 88341

    Office

    $129.42

    Facility

    Unavailable

    $27.83 higher than Chico for the office setting.

  • San Jose-Sunnyvale-Santa Clara (Santa Clara Cnty)

    California · 88341

    Office

    $129.37

    Facility

    Unavailable

    $27.78 higher than Chico for the office setting.

  • San Luis Obispo-Paso Robles

    California · 88341

    Office

    $104.84

    Facility

    Unavailable

    $3.25 higher than Chico for the office setting.

  • Santa Cruz-Watsonville

    California · 88341

    Office

    $110.65

    Facility

    Unavailable

    $9.06 higher than Chico for the office setting.

  • Santa Maria-Santa Barbara

    California · 88341

    Office

    $107.08

    Facility

    Unavailable

    $5.49 higher than Chico for the office setting.

  • Santa Rosa-Petaluma

    California · 88341

    Office

    $111.80

    Facility

    Unavailable

    $10.21 higher than Chico for the office setting.

  • Stockton

    California · 88341

    Office

    $101.59

    Facility

    Unavailable

    The same base rate than Chico for the office setting.

  • Vallejo

    California · 88341

    Office

    $119.17

    Facility

    Unavailable

    $17.58 higher than Chico for the office setting.

  • Visalia

    California · 88341

    Office

    $101.59

    Facility

    Unavailable

    The same base rate than Chico for the office setting.

  • Yuba City

    California · 88341

    Office

    $101.59

    Facility

    Unavailable

    The same base rate than Chico for the office setting.

  • Dc + Md/Va Suburbs

    District of Columbia · 88341

    Office

    $108.66

    Facility

    Unavailable

    $7.07 higher than Chico for the office setting.

  • Miami

    Florida · 88341

    Office

    $97.80

    Facility

    Unavailable

    $3.79 lower than Chico for the office setting.

  • Chicago

    Illinois · 88341

    Office

    $95.13

    Facility

    Unavailable

    $6.46 lower than Chico for the office setting.

  • Manhattan

    New York · 88341

    Office

    $107.79

    Facility

    Unavailable

    $6.20 higher than Chico for the office setting.

  • Alaska*

    Alaska · 88341

    Office

    $108.13

    Facility

    Unavailable

    $6.54 higher than Chico for the office setting.

  • Alabama

    Alabama · 88341

    Office

    $84.61

    Facility

    Unavailable

    $16.98 lower than Chico for the office setting.

  • Arkansas

    Arkansas · 88341

    Office

    $83.39

    Facility

    Unavailable

    $18.20 lower than Chico for the office setting.

  • Arizona

    Arizona · 88341

    Office

    $91.80

    Facility

    Unavailable

    $9.79 lower than Chico for the office setting.

  • Colorado

    Colorado · 88341

    Office

    $99.17

    Facility

    Unavailable

    $2.42 lower than Chico for the office setting.

  • Connecticut

    Connecticut · 88341

    Office

    $100.44

    Facility

    Unavailable

    $1.15 lower than Chico for the office setting.

  • Delaware

    Delaware · 88341

    Office

    $93.34

    Facility

    Unavailable

    $8.25 lower than Chico for the office setting.

  • Fort Lauderdale

    Florida · 88341

    Office

    $95.44

    Facility

    Unavailable

    $6.15 lower than Chico for the office setting.

  • Rest Of Florida

    Florida · 88341

    Office

    $91.04

    Facility

    Unavailable

    $10.55 lower than Chico for the office setting.

  • Atlanta

    Georgia · 88341

    Office

    $95.52

    Facility

    Unavailable

    $6.07 lower than Chico for the office setting.

  • Rest Of Georgia

    Georgia · 88341

    Office

    $86.10

    Facility

    Unavailable

    $15.49 lower than Chico for the office setting.

  • Hawaii, Guam

    Hawaii · 88341

    Office

    $104.39

    Facility

    Unavailable

    $2.80 higher than Chico for the office setting.

  • Iowa

    Iowa · 88341

    Office

    $87.57

    Facility

    Unavailable

    $14.02 lower than Chico for the office setting.

  • Idaho

    Idaho · 88341

    Office

    $87.98

    Facility

    Unavailable

    $13.61 lower than Chico for the office setting.

  • East St. Louis

    Illinois · 88341

    Office

    $88.49

    Facility

    Unavailable

    $13.10 lower than Chico for the office setting.

  • Rest Of Illinois

    Illinois · 88341

    Office

    $87.81

    Facility

    Unavailable

    $13.78 lower than Chico for the office setting.

  • Suburban Chicago

    Illinois · 88341

    Office

    $96.62

    Facility

    Unavailable

    $4.97 lower than Chico for the office setting.

  • Indiana

    Indiana · 88341

    Office

    $88.51

    Facility

    Unavailable

    $13.08 lower than Chico for the office setting.

  • Kansas

    Kansas · 88341

    Office

    $86.78

    Facility

    Unavailable

    $14.81 lower than Chico for the office setting.

  • Kentucky

    Kentucky · 88341

    Office

    $85.78

    Facility

    Unavailable

    $15.81 lower than Chico for the office setting.

  • New Orleans

    Louisiana · 88341

    Office

    $89.78

    Facility

    Unavailable

    $11.81 lower than Chico for the office setting.

  • Rest Of Louisiana

    Louisiana · 88341

    Office

    $85.50

    Facility

    Unavailable

    $16.09 lower than Chico for the office setting.

  • Metropolitan Boston

    Massachusetts · 88341

    Office

    $109.55

    Facility

    Unavailable

    $7.96 higher than Chico for the office setting.

  • Rest Of Massachusetts

    Massachusetts · 88341

    Office

    $98.42

    Facility

    Unavailable

    $3.17 lower than Chico for the office setting.

  • Baltimore/Surr. Cntys

    Maryland · 88341

    Office

    $100.07

    Facility

    Unavailable

    $1.52 lower than Chico for the office setting.

  • Rest Of Maryland

    Maryland · 88341

    Office

    $95.25

    Facility

    Unavailable

    $6.34 lower than Chico for the office setting.

  • Rest Of Maine

    Maine · 88341

    Office

    $88.03

    Facility

    Unavailable

    $13.56 lower than Chico for the office setting.

  • Southern Maine

    Maine · 88341

    Office

    $93.39

    Facility

    Unavailable

    $8.20 lower than Chico for the office setting.

  • Detroit

    Michigan · 88341

    Office

    $91.78

    Facility

    Unavailable

    $9.81 lower than Chico for the office setting.

  • Rest Of Michigan

    Michigan · 88341

    Office

    $87.67

    Facility

    Unavailable

    $13.92 lower than Chico for the office setting.

  • Minnesota

    Minnesota · 88341

    Office

    $96.14

    Facility

    Unavailable

    $5.45 lower than Chico for the office setting.

  • Metropolitan Kansas City

    Missouri · 88341

    Office

    $89.58

    Facility

    Unavailable

    $12.01 lower than Chico for the office setting.

  • Metropolitan St. Louis

    Missouri · 88341

    Office

    $90.57

    Facility

    Unavailable

    $11.02 lower than Chico for the office setting.

  • Rest Of Missouri

    Missouri · 88341

    Office

    $83.76

    Facility

    Unavailable

    $17.83 lower than Chico for the office setting.

  • Mississippi

    Mississippi · 88341

    Office

    $83.61

    Facility

    Unavailable

    $17.98 lower than Chico for the office setting.

  • Montana**

    Montana · 88341

    Office

    $94.19

    Facility

    Unavailable

    $7.40 lower than Chico for the office setting.

  • North Carolina

    North Carolina · 88341

    Office

    $89.01

    Facility

    Unavailable

    $12.58 lower than Chico for the office setting.

  • North Dakota**

    North Dakota · 88341

    Office

    $93.99

    Facility

    Unavailable

    $7.60 lower than Chico for the office setting.

  • Nebraska

    Nebraska · 88341

    Office

    $88.17

    Facility

    Unavailable

    $13.42 lower than Chico for the office setting.

  • New Hampshire

    New Hampshire · 88341

    Office

    $97.24

    Facility

    Unavailable

    $4.35 lower than Chico for the office setting.

  • Northern Nj

    New Jersey · 88341

    Office

    $107.45

    Facility

    Unavailable

    $5.86 higher than Chico for the office setting.

  • Rest Of New Jersey

    New Jersey · 88341

    Office

    $101.90

    Facility

    Unavailable

    $0.31 higher than Chico for the office setting.

  • New Mexico

    New Mexico · 88341

    Office

    $87.99

    Facility

    Unavailable

    $13.60 lower than Chico for the office setting.

  • Nevada**

    Nevada · 88341

    Office

    $94.21

    Facility

    Unavailable

    $7.38 lower than Chico for the office setting.

  • Nyc Suburbs/Long Island

    New York · 88341

    Office

    $109.92

    Facility

    Unavailable

    $8.33 higher than Chico for the office setting.

  • Poughkpsie/N Nyc Suburbs

    New York · 88341

    Office

    $102.26

    Facility

    Unavailable

    $0.67 higher than Chico for the office setting.

  • Queens

    New York · 88341

    Office

    $109.25

    Facility

    Unavailable

    $7.66 higher than Chico for the office setting.

  • Rest Of New York

    New York · 88341

    Office

    $90.32

    Facility

    Unavailable

    $11.27 lower than Chico for the office setting.

  • Ohio

    Ohio · 88341

    Office

    $87.63

    Facility

    Unavailable

    $13.96 lower than Chico for the office setting.

  • Oklahoma

    Oklahoma · 88341

    Office

    $86.04

    Facility

    Unavailable

    $15.55 lower than Chico for the office setting.

  • Portland

    Oregon · 88341

    Office

    $102.78

    Facility

    Unavailable

    $1.19 higher than Chico for the office setting.

  • Rest Of Oregon

    Oregon · 88341

    Office

    $93.79

    Facility

    Unavailable

    $7.80 lower than Chico for the office setting.

  • Metropolitan Philadelphia

    Pennsylvania · 88341

    Office

    $97.68

    Facility

    Unavailable

    $3.91 lower than Chico for the office setting.

  • Rest Of Pennsylvania

    Pennsylvania · 88341

    Office

    $87.98

    Facility

    Unavailable

    $13.61 lower than Chico for the office setting.

  • Puerto Rico

    Puerto Rico · 88341

    Office

    $95.02

    Facility

    Unavailable

    $6.57 lower than Chico for the office setting.

  • Rhode Island

    Rhode Island · 88341

    Office

    $96.99

    Facility

    Unavailable

    $4.60 lower than Chico for the office setting.

  • South Carolina

    South Carolina · 88341

    Office

    $88.40

    Facility

    Unavailable

    $13.19 lower than Chico for the office setting.

  • South Dakota**

    South Dakota · 88341

    Office

    $93.97

    Facility

    Unavailable

    $7.62 lower than Chico for the office setting.

  • Tennessee

    Tennessee · 88341

    Office

    $87.17

    Facility

    Unavailable

    $14.42 lower than Chico for the office setting.

  • Austin

    Texas · 88341

    Office

    $98.57

    Facility

    Unavailable

    $3.02 lower than Chico for the office setting.

  • Beaumont

    Texas · 88341

    Office

    $87.37

    Facility

    Unavailable

    $14.22 lower than Chico for the office setting.

  • Brazoria

    Texas · 88341

    Office

    $93.58

    Facility

    Unavailable

    $8.01 lower than Chico for the office setting.

  • Dallas

    Texas · 88341

    Office

    $94.01

    Facility

    Unavailable

    $7.58 lower than Chico for the office setting.

  • Fort Worth

    Texas · 88341

    Office

    $93.26

    Facility

    Unavailable

    $8.33 lower than Chico for the office setting.

  • Galveston

    Texas · 88341

    Office

    $93.75

    Facility

    Unavailable

    $7.84 lower than Chico for the office setting.

  • Houston

    Texas · 88341

    Office

    $93.93

    Facility

    Unavailable

    $7.66 lower than Chico for the office setting.

  • Rest Of Texas

    Texas · 88341

    Office

    $90.31

    Facility

    Unavailable

    $11.28 lower than Chico for the office setting.

  • Utah

    Utah · 88341

    Office

    $89.63

    Facility

    Unavailable

    $11.96 lower than Chico for the office setting.

  • Virginia

    Virginia · 88341

    Office

    $92.81

    Facility

    Unavailable

    $8.78 lower than Chico for the office setting.

  • Virgin Islands

    United States Virgin Islands · 88341

    Office

    $95.02

    Facility

    Unavailable

    $6.57 lower than Chico for the office setting.

  • Vermont

    Vermont · 88341

    Office

    $93.27

    Facility

    Unavailable

    $8.32 lower than Chico for the office setting.

  • Rest Of Washington

    Washington · 88341

    Office

    $98.35

    Facility

    Unavailable

    $3.24 lower than Chico for the office setting.

  • Seattle (King Cnty)

    Washington · 88341

    Office

    $112.18

    Facility

    Unavailable

    $10.59 higher than Chico for the office setting.

  • Wisconsin

    Wisconsin · 88341

    Office

    $90.79

    Facility

    Unavailable

    $10.80 lower than Chico for the office setting.

  • West Virginia

    West Virginia · 88341

    Office

    $84.45

    Facility

    Unavailable

    $17.14 lower than Chico for the office setting.

  • Wyoming**

    Wyoming · 88341

    Office

    $94.10

    Facility

    Unavailable

    $7.49 lower than Chico for the office setting.

See how rates vary across the country

88341 · Office / nonfacility · Non-QP. Choose a state to explore its payment localities. A range means the amount varies within that state.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$83.39

$115.51

Color shows the midpoint of each state’s locality range.

View all state and territory rates as a table
State / territoryRate rangeLocalities
AK$108.131
AL$84.611
AR$83.391
AZ$91.801
CA$101.59–$129.4229
CO$99.171
CT$100.441
DC$108.661
DE$93.341
FL$91.04–$97.803
GA$86.10–$95.522
GU$104.391
HI$104.391
IA$87.571
ID$87.981
IL$87.81–$96.624
IN$88.511
KS$86.781
KY$85.781
LA$85.50–$89.782
MA$98.42–$109.552
MD$95.25–$108.663
ME$88.03–$93.392
MI$87.67–$91.782
MN$96.141
MO$83.76–$90.573
MS$83.611
MT$94.191
NC$89.011
ND$93.991
NE$88.171
NH$97.241
NJ$101.90–$107.452
NM$87.991
NV$94.211
NY$90.32–$109.925
OH$87.631
OK$86.041
OR$93.79–$102.782
PA$87.98–$97.682
PR$95.021
RI$96.991
SC$88.401
SD$93.971
TN$87.171
TX$87.37–$98.578
UT$89.631
VA$92.81–$108.662
VI$95.021
VT$93.271
WA$98.35–$112.182
WI$90.791
WV$84.451
WY$94.101

Explore 88341 on the national rate map →

Where does this rate apply?

Chico is a Medicare payment area. Our Census mapping connects it to 30 cities and communities in California, including the examples shown here.

Some communities span more than one payment area. Follow a city link to compare all of its mapped areas, or check the service-location ZIP above for an address-level starting point.

Browse all communities in California →

Use this rate

What is a percentage of Medicare worth?

Turn a percentage into dollars for 88341 in Chico. This uses the base rate on this page, so the locality and release stay consistent.

Reference amount per service

$111.75

$101.59 × 110% = $111.75

A contract may specify another Medicare year or additional adjustments. This is percentage arithmetic on the displayed base rate, not a claim adjudication.

Working with a whole code list?

Compare an offer across your annual code mix, including an older Medicare schedule or flat per-code rates.

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How this local rate is calculated

Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 88341 in Chico.

PPRRVU2026_Oct_nonQPP.csv

11,248

Code
88341
Physician work
0.55
Practice expense
2.26
Malpractice
0.01

GPCI2026.csv

9

Locality
Chico
Physician work
1.017
Practice expense
1.096
Malpractice
0.536
Office / nonfacility calculation for 88341 in Chico
ComponentRVULocality factorAdjusted
Physician work0.55× 1.0170.5594
Practice expense2.26× 1.0962.4770
Malpractice0.01× 0.5360.0054
Total RVUs3.0417
Conversion factor× 33.4009

Office / nonfacility rate, Chico$101.59

Values as parsed from CMS release RVU26D, effective 2026-10-01. The amount is rounded to the nearest cent only at the end.

Open 88341 in the RVU calculator →

Explore RVUs, geographic factors and the full formula

Office / nonfacility

Office / nonfacility calculation inputs
ComponentRVULocal GPCI
Work0.551.017
Practice expense2.261.096
Malpractice0.010.536

(0.55 × 1.017 + 2.26 × 1.096 + 0.01 × 0.536) × $33.4009 = $101.59

The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.

How this rate has changed

88341 · Office / nonfacility

$101.59

Effective 2026-10-01

The base rate is $1.02 higher than on 2025-10-01, moving from $100.57 to $101.59 (1.0%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $100.57changed to$101.59

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.56 changed to 0.55
    • Practice expense RVU 2.32 changed to 2.26
    • Work GPCI 1.014 changed to 1.017
    • Practice expense GPCI 1.093 changed to 1.096
    • Malpractice GPCI 0.560 changed to 0.536

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    Earliest loaded release: $100.57

    Held through RVU25B, RVU25C, RVU25D.

Explore release dates and calculate this code in an earlier period →

Each row uses the accepted CMS release effective on that date and the same contractor and locality identifiers. Missing rates stay visible. Historical boundaries may differ; verify the service address for an older claim.

Inspect every release and its CMS source
Effective fromOffice / nonfacilityFacilityCMS release
2026-10-01$101.59Not available in this settingRVU26D
2026-07-01$101.59Not available in this settingRVU26C
2026-04-01$101.59Not available in this settingRVU26B
2026-01-01$101.59Not available in this settingRVU26A
2025-10-01$100.57Not available in this settingRVU25D
2025-07-01$100.57Not available in this settingRVU25C
2025-04-01$100.57Not available in this settingRVU25B
2025-01-01$100.57Not available in this settingRVU25A

88341 billing questions

How do I split units between 88342 and 88341 when several specimens are stained?

Report 88342 for the initial single-antibody stain on each separately identified specimen. Report one unit of 88341 for each distinct additional single-antibody stain on that specimen, not for another slide or block stained with the same antibody.

Can 88341 be billed without a primary procedure?

No. It is an add-on code; report it with 88342 for the initial single-antibody stain on the same specimen.

When is a stain reported with 88344 rather than 88341?

Use 88344 for a multiplex stain procedure that produces distinguishable results from multiple antibodies. Use 88341 for an additional, separate single-antibody stain on the specimen.

Can 88341 be reported for the same antibody quantified with 88360 or 88361?

No. Do not also report a qualitative immunostain code for the same antibody on the same specimen when its morphometric analysis is reported with 88360 or 88361.

Which modifier identifies the pathologist’s interpretation when another entity stains the slides?

Report the separately billed interpretation with modifier 26; modifier TC identifies the separately billed technical work. When one entity bills both components, report the global service without either modifier.

Do control slides count as additional units?

No. Positive and negative control slides do not generate additional units of 88341.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.

Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.

RVUs for 88341PPRRVU2026_Oct_nonQPP.csv, line 11,248 (RVU26D)
Geographic factors for ChicoGPCI2026.csv, line 9 (RVU26D)
Open CMS sourceHow this rate is calculatedBuild a fee sheet