Billing code 41100: Tongue biopsyMedicare rate & RVUs in Delaware

Reports tissue sampling from a lesion in the anterior two-thirds of the tongue for microscopic diagnosis, rather than complete lesion removal.

CMS RVU26DEffective Oct 1, 20261 payment locality6.6K Medicare services in 2024

Medicare pays $186.01 for 41100 in the office in Delaware (Delaware). Which amount applies depends on the service address.

$186.01Office (non-facility)
$96.58Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 41100 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Delaware
  2. What 41100 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 41100 covers

This service samples tissue from the front two-thirds of the tongue, from the tip through the body, for pathologic examination. An otolaryngologist, oral and maxillofacial surgeon, or other qualified clinician may perform it in an office or facility. Common reasons include evaluating a persistent tongue ulcer or a suspicious white or red mucosal patch. The biopsy obtains diagnostic tissue; it is not reported in place of an excision that removes the lesion.

Document the exact tongue site, the clinical concern, and the tissue obtained for examination. Choose the posterior-tongue biopsy code when the sampled site is in the back third, and use a floor-of-mouth code for tissue from that separate site. Medicare assigns a 10-day global period, so related postoperative visits during that period are included. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and the others at 50%. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this service; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

41100 in Delaware

41100 office and facility rates by payment locality
Payment localityOfficeFacility
Delaware$186.01$96.58

How the 41100 rate is calculated

Each of 41100’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 41100

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.38Practice expense 4.06Malpractice 0.19

5.6300 adjusted RVUs×$33.4009 conversion factor=$188.05

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 41100

41100 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 41100

Tongue biopsy

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 41100

Tongue biopsy

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

41100 without 51 · national office

$188.05

Tongue biopsy

41100-51 · Second procedure: 50%

$94.03

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

41100 compared with similar codes

Compare codes

41100 vs 41105 vs 41108 vs 41110: national Medicare rates

Swap in your local Medicare rate.

  • 41100
    Tongue biopsy · 1.38 wRVU
    $188.05
  • 41105
    Tongue biopsy · 1.43 wRVU
    $189.38+$1.33
  • 41108
    Oral biopsy · 1.07 wRVU
    $170.01−$18.04
  • 41110
    Tongue lesion excision · 1.52 wRVU
    $226.79+$38.74

How to choose

41105Tongue biopsy
Use 41100 for a biopsy from the anterior two-thirds of the tongue; 41105 is for a biopsy from the posterior third.
41108Oral biopsy
41108 applies to a biopsy of the floor of the mouth. Use 41100 only when the sampled tissue is tongue tissue.
41110Tongue lesion excision
41100 represents diagnostic tissue sampling. 41110 is for excision of a tongue lesion rather than a biopsy.

41100 billing questions

How does 41100 differ from 41105?

41100 is for sampling the anterior two-thirds of the tongue. Use 41105 when the biopsy site is in the posterior third.

Should 41100 be used when the entire lesion is removed?

No. This code describes diagnostic tissue sampling; select the applicable tongue-lesion excision code when the lesion is removed.

Can the pathology examination be billed separately?

The tissue examination is a separate laboratory service when performed and reported by the laboratory. The biopsy claim represents the clinician's sampling procedure.

Is modifier 50 appropriate for biopsies on both sides of the tongue?

No. CMS identifies bilateral adjustment as inappropriate for this code.

How are other procedures in the same session paid?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and the remaining procedures at 50%. Related postoperative visits are included for 10 days.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 41100PPRRVU2026_Oct_nonQPP.csv, line 4,895 (RVU26D)
Geographic factors for DelawareGPCI2026.csv, line 40 (RVU26D)

Open CMS sourceHow we calculate rates

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