Billing code 58110: Endometrial biopsyMedicare rate & RVUs in Florida

Reports endometrial tissue sampling performed during a colposcopy when the uterine lining is evaluated separately from cervical or vaginal tissue.

CMS RVU26DEffective Oct 1, 20263 payment localities671 Medicare services in 2024

Medicare pays $52.51–$59.13 for 58110 in the office in Florida, from Rest Of Florida to Miami. Which amount applies depends on the service address.

$52.51–$59.13Office (non-facility)
$37.51–$42.79Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 58110 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Florida
  2. What 58110 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 58110 covers

This add-on represents a sample of the uterine lining obtained while the clinician performs a colposcopy. An OB-GYN or other qualified clinician may use an office endometrial sampler to investigate a uterine concern, such as abnormal bleeding, during a visit that also evaluates an abnormal cervical screening result. The endometrial specimen is distinct from tissue taken from the cervix or endocervical canal during colposcopy.

Report 58110 only with the primary colposcopy procedure; use 58100 for endometrial sampling performed without colposcopy. The record should identify the colposcopy and separately document endometrial sampling, its indication, method, and specimen. Cervical biopsy or endocervical curettage alone does not represent sampling of the uterine lining. CMS pays this add-on within the primary procedure's global period, so payment is associated with that primary service's global period.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 58110 pays more and less in Florida

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

3 payment localities

$52.51 to $59.13

$52.51$55.82$59.13
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
58110 office and facility rates by payment locality
Payment localityOfficeFacility
Fort Lauderdale$55.16$39.26
Miami$59.13$42.79
Rest Of Florida$52.51$37.51

How the 58110 rate is calculated

Each of 58110’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 58110

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.75Practice expense 0.64Malpractice 0.14

1.5300 adjusted RVUs×$33.4009 conversion factor=$51.10

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 58110

The CMS indicators that decide how 58110 is paid alongside other services.

CMS payment indicators · 58110

Endometrial biopsy

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

58110 compared with similar codes

Compare codes

58110 vs 58100 vs 57454 vs 57456: national Medicare rates

Swap in your local Medicare rate.

  • 58110
    Endometrial biopsy · 0.75 wRVU
    $51.10
  • 58100
    Endometrial biopsy · 1.18 wRVU
    $98.20+$47.10
  • 57454
    Cervical colposcopy · 2.27 wRVU
    $166.00+$114.90
  • 57456
    Cervical colposcopy · 1.8 wRVU
    $150.64+$99.54

How to choose

58100Endometrial biopsy
58100 describes endometrial sampling without colposcopy. Use 58110 when the endometrial sample is obtained in conjunction with a colposcopy.
57454Cervical colposcopy
57454 covers colposcopy with cervical biopsy and endocervical curettage. It does not represent a separate sample from the uterine lining.
57456Cervical colposcopy
57456 covers colposcopy with endocervical curettage. 58110 represents endometrial sampling, a distinct specimen site.

58110 billing questions

When should 58110 be reported instead of 58100?

Report 58110 when endometrial sampling is performed in conjunction with a colposcopy. Use 58100 for endometrial sampling performed without colposcopy.

Does a cervical biopsy or endocervical curettage support 58110?

No. The add-on represents sampling of the uterine lining; cervical biopsy and endocervical curettage sample different sites.

Which primary procedure is reported with 58110?

Report it with the appropriate primary colposcopy procedure. The add-on is paid within that primary procedure's global period.

What documentation supports 58110?

Document the colposcopy and the separate endometrial sampling, including the indication, sampling method, and uterine lining specimen.

Can 58110 be reported for a stand-alone endometrial biopsy?

No. This is an add-on for endometrial sampling performed with colposcopy; 58100 is the relevant code for sampling without colposcopy.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 58110PPRRVU2026_Oct_nonQPP.csv, line 6,517 (RVU26D)

Open CMS sourceHow we calculate rates

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