HCPCS Q4110: Wound matrixMedicare rate & RVUs in Florida

Reports PriMatrix fetal bovine dermal matrix supplied for wound coverage, measured by square centimeter and paired with the applicable application procedure.

CMS RVU26DEffective Oct 1, 20263 payment localities

Medicare pays $121.66–$132.47 for Q4110 in the office in Florida, from Rest Of Florida to Miami. Which amount applies depends on the service address.

$121.66–$132.47Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4110 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Florida
  2. What Q4110 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4110 covers

Q4110 identifies PriMatrix, a fetal bovine dermal matrix supplied for wound coverage, including treatment of chronic ulcers and other wounds. Wound-care clinicians and surgeons may use it in outpatient wound clinics, hospital outpatient departments, or other settings where a skin substitute is applied. The code represents the product, not the work of preparing the wound or applying the matrix.

Report the quantity in square centimeters and document the product and wound area treated. Pair Q4110 with the primary skin-substitute application procedure that matches the treatment site and wound area; for example, 15271 may apply to an eligible trunk, arm, or leg wound within its area threshold. CMS classifies Q4110 as an add-on, so it is billed only with a primary procedure and paid within that procedure’s global period. CMS also identifies it as technical-component-only, with interpretation covered by a separate code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4110 pays more and less in Florida

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

3 payment localities

$121.66 to $132.47

$121.66$127.06$132.47
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
Q4110 office and facility rates by payment locality
Payment localityOfficeFacility
Fort Lauderdale$128.91Unavailable
Miami$132.47Unavailable
Rest Of Florida$121.66Unavailable

How the Q4110 rate is calculated

Each of Q4110’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4110

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4110

The CMS indicators that decide how Q4110 is paid alongside other services.

CMS payment indicators · Q4110

Wound matrix

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4110 compared with similar codes

Compare codes

Q4110 vs Q4102 vs Q4104 vs 15271: national Medicare rates

Swap in your local Medicare rate.

  • Q4110
    Wound matrix · 0 wRVU
    $127.26
  • Q4102
    Wound matrix · 0 wRVU
    $127.26+$0.00
  • Q4104
    Wound matrix · 0 wRVU
    $127.26+$0.00
  • 15271
    Skin substitute graft · 1.46 wRVU
    $157.99+$30.73

How to choose

Q4102Wound matrix
Q4102 identifies Oasis wound matrix; Q4110 identifies PriMatrix. Select the product code matching the material actually supplied.
Q4104Wound matrix
Q4104 identifies Integra BM wound matrix, not PriMatrix. These are separate product codes, not alternate descriptions of the same supply.
15271Skin substitute graft
15271 reports application work for eligible skin-substitute treatment on the trunk, arms, or legs. Q4110 reports the PriMatrix product by square centimeter and is paired with the applicable primary procedure.

Q4110 billing questions

Does Q4110 report the PriMatrix application?

No. Q4110 reports the PriMatrix product by square centimeter. Report the applicable skin-substitute application procedure separately as the primary service.

What should support the number of units?

Document that PriMatrix was used and the square-centimeter quantity represented by the product supplied for the wound treatment.

Can Q4110 be billed by itself?

No. CMS identifies it as an add-on code that must be billed with a primary procedure, and payment falls within that procedure’s global period.

Is Q4110 the same as Q4102 or Q4104?

No. Q4110 identifies PriMatrix; Q4102 and Q4104 identify different wound-matrix products. Report the code for the product actually used.

How does the technical-component designation affect reporting?

CMS classifies Q4110 as technical-component-only and indicates that a separate code covers interpretation. Q4110 itself identifies the PriMatrix product.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4110PPRRVU2026_Oct_nonQPP.csv, line 18,208 (RVU26D)

Open CMS sourceHow we calculate rates

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