HCPCS Q4249: AmniplyMedicare rate & RVUs in Florida

Reports the Amniply amniotic membrane product by square centimeter when furnished for application to a wound during a separately coded wound procedure.

CMS RVU26DEffective Oct 1, 20263 payment localities3.9K Medicare services in 2024

Medicare pays $121.66–$132.47 for Q4249 in the office in Florida, from Rest Of Florida to Miami. Which amount applies depends on the service address.

$121.66–$132.47Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4249 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Florida
  2. What Q4249 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4249 covers

Q4249 represents the Amniply amniotic membrane product supplied for wound treatment, measured by the square centimeter. Wound-care clinicians, surgeons, and podiatrists may use it when applying the product to a prepared wound bed in an office or other treatment setting. The code identifies the product, not the wound preparation or application service itself.

Report the number of square centimeters represented by the Amniply product furnished, and retain documentation identifying the product and supporting the quantity reported. CMS classifies Q4249 as an add-on code: bill it only with a primary procedure, such as an applicable skin-substitute application procedure, and payment is within that procedure’s global period. It is a technical-component-only code; a separate code covers interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4249 pays more and less in Florida

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

3 payment localities

$121.66 to $132.47

$121.66$127.06$132.47
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
Q4249 office and facility rates by payment locality
Payment localityOfficeFacility
Fort Lauderdale$128.91Unavailable
Miami$132.47Unavailable
Rest Of Florida$121.66Unavailable

How the Q4249 rate is calculated

Each of Q4249’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4249

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4249

The CMS indicators that decide how Q4249 is paid alongside other services.

CMS payment indicators · Q4249

Amniply

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4249 compared with similar codes

Compare codes

Q4249 vs Q4247 vs Q4248 vs Q4239: national Medicare rates

Swap in your local Medicare rate.

  • Q4249
    Amniply · 0 wRVU
    $127.26
  • Q4247
    Amniotext patch · 0 wRVU
    $127.26+$0.00
  • Q4248
    Wound allograft · 0 wRVU
    $127.26+$0.00
  • Q4239
    Amniotic graft · 0 wRVU
    $127.26+$0.00

How to choose

Q4247Amniotext patch
Q4247 identifies Amniotext patch, while Q4249 identifies Amniply. Use the code matching the product furnished.
Q4248Wound allograft
Q4248 identifies Dermacyte amniotic membrane allograft. Q4249 is specific to Amniply; the similar tissue category does not make the product codes interchangeable.
Q4239Amniotic graft
Q4239 identifies Amnio-maxx or lite rather than Amniply. Select according to the product used, not just the shared square-centimeter billing unit.

Q4249 billing questions

How is Q4249 different from the skin-substitute application code?

Q4249 reports the Amniply product by square centimeter. The primary application code reports the wound application service.

Can Q4249 be billed by itself?

No. CMS identifies Q4249 as an add-on code that must be billed with a primary procedure.

What quantity should be reported?

Report the square centimeters of Amniply product furnished. Documentation should identify the product and support the quantity.

Is a separate interpretation code needed?

CMS classifies Q4249 as technical-component-only and specifies that a separate code covers interpretation.

How does the global-period rule affect payment?

Payment for Q4249 is within the primary procedure’s global period, so it is not paid separately from that procedure’s global payment.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4249PPRRVU2026_Oct_nonQPP.csv, line 18,337 (RVU26D)

Open CMS sourceHow we calculate rates

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