Billing code 27323: Soft-tissue biopsyMedicare rate & RVUs in Guam

Reports surgical sampling of superficial soft tissue in the thigh or knee area when a lesion requires tissue diagnosis rather than complete removal.

CMS RVU26DEffective Oct 1, 20261 payment locality396 Medicare services in 2024

Medicare pays $296.57 for 27323 in the office in Guam (Hawaii, Guam). Which amount applies depends on the service address.

$296.57Office (non-facility)
$163.27Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 27323 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Guam
  2. What 27323 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 27323 covers

A surgeon removes a sample of superficial soft tissue from the thigh or knee area so the tissue can be examined for a suspected tumor or other abnormality. Orthopedic surgeons and surgical oncologists commonly perform the procedure in an outpatient operating room or procedure setting. The code distinguishes a superficial biopsy from sampling deeper soft tissue and from biopsy of the knee joint lining.

Report this code when the operative record supports sampling superficial tissue, rather than complete excision of the lesion. Document the biopsy site, the tissue sampled, and the operative findings; the pathology service may be reported separately when performed by another provider. This minor procedure has a 10-day global period, which includes related postoperative visits during that period. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and other procedures are paid at 50%. For bilateral reporting, modifier 50 is paid at 150%. Medicare does not pay an assistant at surgery for this procedure; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

27323 in Hawaii, Guam

27323 office and facility rates by payment locality
Payment localityOfficeFacility
Hawaii, Guam$296.57$163.27

How the 27323 rate is calculated

Each of 27323’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 27323

RVUs × geographic indexes × conversion factor

Work2.27

2.27 RVUs× 1.000 GPCI

Practice expense5.66

5.66 RVUs× 1.000 GPCI

Malpractice0.30

0.30 RVUs× 1.000 GPCI

Adjusted RVUs

8.2300

Conversion factor

$33.4009

Medicare rate

$274.89

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 27323

27323 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 27323

Soft-tissue biopsy

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)1Bilateral with modifier 50 pays 150% of the fee schedule amount.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 27323

Soft-tissue biopsy

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 50 · payment effect

With and without the modifier

27323 without 50 · national office

$274.89

Soft-tissue biopsy

27323-50 · Bilateral: 150%

$412.34

Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).

When to use modifier 50

27323 compared with similar codes

Compare codes · National

5 codes, side by side

  • 27323

    Soft-tissue biopsy2.27 wRVU

    $274.89

  • 27324

    Thigh biopsy4.91 wRVU

    Not priced

  • 27327

    Soft-tissue excision3.86 wRVU

    $539.42+$264.53

  • 27328

    Soft-tissue tumor excision8.63 wRVU

    Not priced

  • 27330

    Knee biopsy4.98 wRVU

    Not priced

How to choose

27324Thigh biopsy
This code is for superficial soft tissue; 27324 is for deep soft-tissue biopsy. Use the operative description of tissue depth to distinguish them.
27327Soft-tissue excision
Use this biopsy code when tissue is sampled. Code 27327 describes excision of a superficial thigh or knee-area lesion under its applicable size criterion.
27328Soft-tissue tumor excision
This code reports superficial tissue sampling, while 27328 describes excision of a deep thigh or knee-area tumor under its applicable size criterion.
27330Knee biopsy
This code samples superficial soft tissue around the thigh or knee; 27330 is for biopsy of the knee joint lining.

27323 billing questions

How do I distinguish this code from 27324?

Use 27323 for sampling superficial soft tissue in the thigh or knee area. Use 27324 when the biopsy is of deep soft tissue; the operative documentation should support the depth.

When is an excision code more appropriate?

This code describes sampling tissue, not removing the entire lesion. When the surgeon excises a superficial lesion or a deep tumor, consider the applicable excision code, such as 27327 or 27328, based on the documented procedure and lesion.

Can pathology be billed separately?

The surgeon's biopsy service and a pathologist's examination of the specimen are distinct services when each is performed and otherwise reportable. The operative record should identify the submitted tissue and the pathology report should document the examination.

What supports reporting the superficial level?

Document the thigh or knee-area site, the tissue sampled, and operative details that establish the biopsy was superficial rather than deep. A diagnosis of a mass alone does not establish the depth.

How does the 10-day global period affect follow-up?

Related postoperative visits during the 10 days after the biopsy are included in the global period. If other procedures are performed in the same session, the highest-valued procedure is paid in full and the others are subject to the multiple-procedure reduction.

How is a bilateral biopsy reported?

For a bilateral procedure, report modifier 50; CMS pays the bilateral service at 150%. An assistant at surgery is not paid, and co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 27323PPRRVU2026_Oct_nonQPP.csv, line 2,834 (RVU26D)
Geographic factors for Hawaii, GuamGPCI2026.csv, line 46 (RVU26D)

Open CMS sourceHow we calculate rates

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