Billing code 56605: Vulvar biopsyMedicare rate & RVUs in Guam

Report this procedure when a clinician samples a single vulvar or perineal lesion for tissue diagnosis rather than removing vulvar tissue definitively.

CMS RVU26DEffective Oct 1, 20261 payment locality26.3K Medicare services in 2024

Medicare pays $97.90 for 56605 in the office in Guam (Hawaii, Guam). Which amount applies depends on the service address.

$97.90Office (non-facility)
$50.43Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 56605 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Guam
  2. What 56605 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 56605 covers

A clinician takes tissue from one vulvar or perineal lesion for histopathologic evaluation, often using a punch or incisional sample when examination findings or symptoms warrant diagnosis. Gynecologists and other clinicians managing vulvar disease may perform the biopsy in an office procedure room or facility. Common reasons include evaluating a persistent ulcer, an abnormal pigmented area, focal thickening, or a lesion concerning for vulvar intraepithelial neoplasia or malignancy.

Report 56605 for the first lesion sampled and 56606 for each additional separately biopsied lesion. Document the lesion site and number, the clinical reason for sampling, and the biopsy performed. The 0-day global period includes same-day preoperative and postoperative care. When multiple procedures are performed in the same session, the highest-valued is paid in full and others are subject to the standard 50% reduction. Modifier 50 is inappropriate, even for lesions on both sides. CMS does not pay an assistant at surgery for this service; co-surgeons are permitted, but team surgery is not.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

56605 in Hawaii, Guam

56605 office and facility rates by payment locality
Payment localityOfficeFacility
Hawaii, Guam$97.90$50.43

How the 56605 rate is calculated

Each of 56605’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 56605

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.07Practice expense 1.54Malpractice 0.19

2.8000 adjusted RVUs×$33.4009 conversion factor=$93.52

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 56605

The CMS indicators that decide how 56605 is paid alongside other services.

CMS payment indicators · 56605

Vulvar biopsy

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)2Permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

56605 without 51 · national office

$93.52

Vulvar biopsy

56605-51 · Second procedure: 50%

$46.76

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

56605 compared with similar codes

Compare codes

56605 vs 56606 vs 56821 vs 56620: national Medicare rates

Swap in your local Medicare rate.

  • 56605
    Vulvar biopsy · 1.07 wRVU
    $93.52
  • 56606
    Vulvar biopsy · 0.54 wRVU
    $39.08−$54.44
  • 56821
    Vulvar colposcopy · 2 wRVU
    $171.01+$77.49
  • 56620
    Vulvectomy · 7.34 wRVU
    —

How to choose

56606Vulvar biopsy
56605 covers the first lesion sampled; 56606 reports each additional separately biopsied lesion.
56821Vulvar colposcopy
Choose 56821 when vulvar colposcopy with biopsy is performed; 56605 describes biopsy without that colposcopy service.
56620Vulvectomy
56620 describes definitive partial vulvar removal. Use 56605 when tissue is sampled for diagnosis rather than removing vulvar tissue as treatment.

56605 billing questions

When should 56606 be reported instead?

Use 56605 for the first lesion biopsied. Report 56606 for each additional, separately sampled lesion.

Can modifier 50 be used for lesions on both sides?

No. The bilateral adjustment does not apply, and modifier 50 is inappropriate for this service.

Is the pathology examination included?

The code covers obtaining the biopsy tissue. Histologic examination is a separate laboratory service when performed and reported by the responsible laboratory.

What documentation supports the code?

Record the vulvar or perineal site, the number of lesions sampled, the clinical reason for biopsy, and the procedure performed.

How does CMS handle other procedures performed in the same session?

The highest-valued procedure is paid in full, with the other procedures subject to the standard multiple procedure reduction. Same-day preoperative and postoperative care is included in the 0-day global period.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 56605PPRRVU2026_Oct_nonQPP.csv, line 6,410 (RVU26D)
Geographic factors for Hawaii, GuamGPCI2026.csv, line 46 (RVU26D)

Open CMS sourceHow we calculate rates

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