HCPCS Q4308: Skin substituteMedicare rate & RVUs in Guam

Reports Sanopellis supplied for wound treatment, measured by square centimeter and billed with the primary procedure for its application.

CMS RVU26DEffective Oct 1, 20261 payment locality

Medicare pays $144.69 for Q4308 in the office in Guam (Hawaii, Guam). Which amount applies depends on the service address.

$144.69Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4308 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Guam
  2. What Q4308 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4308 covers

Q4308 identifies Sanopellis supplied for wound care, such as treatment involving a chronic or nonhealing wound. The product may be used by clinicians performing wound treatment in settings where skin substitute grafts are applied. Report the product code separately from the procedure that applies it; Q4308 represents the Sanopellis supply, not the clinician’s wound preparation or application work.

Select Q4308 when Sanopellis is the product furnished, and report units based on the documented square centimeters. The record should identify the product and support the quantity supplied and used. CMS classifies Q4308 as an add-on: report it only with a primary procedure, and payment falls within that procedure’s global period. CMS also classifies it as technical-component-only, with interpretation covered by a separate code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Q4308 in Hawaii, Guam

Q4308 office and facility rates by payment locality
Payment localityOfficeFacility
Hawaii, Guam$144.69Unavailable

How the Q4308 rate is calculated

Each of Q4308’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4308

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4308

The CMS indicators that decide how Q4308 is paid alongside other services.

CMS payment indicators · Q4308

Skin substitute

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4308 compared with similar codes

Compare codes · National

5 codes, side by side

  • Q4308

    Skin substitute0 wRVU

    $127.26

  • 15271

    Skin substitute graft1.46 wRVU

    $157.99+$30.73

  • Q4307

    Amnion product0 wRVU

    $127.26+$0.00

  • Q4309

    Wound matrix0 wRVU

    $127.26+$0.00

  • Q4310

    Not on the physician fee schedule0 wRVU

    Not priced

How to choose

15271Skin substitute graft
15271 reports the primary skin substitute application service for its applicable sites and wound area; Q4308 reports the Sanopellis product supplied with a primary procedure.
Q4307Amnion product
Q4307 identifies American amnion rather than Sanopellis. Choose the product code that matches what was furnished.
Q4309Wound matrix
Q4309 identifies Via Matrix rather than Sanopellis. Both use a per-square-centimeter unit, but they represent different products.
Q4310Procenta, per 100 mg
Q4310 identifies Procenta and uses a per-100-mg unit; Q4308 identifies Sanopellis and uses a per-square-centimeter unit.

Q4308 billing questions

Is Q4308 the wound application procedure?

No. Q4308 reports the Sanopellis product; report the applicable primary procedure for the clinician’s application work.

Can Q4308 be billed by itself?

No. CMS identifies it as an add-on code that must be billed with a primary procedure.

How are units determined?

The code is measured per square centimeter. Document the Sanopellis product and the square-centimeter quantity supplied and used.

What does the global-period rule mean for payment?

CMS pays Q4308 within the primary procedure’s global period. Report it with the primary procedure rather than as a stand-alone service.

How does Q4308 differ from Q4307 or Q4309?

Those codes identify different products. Use Q4308 only when Sanopellis was furnished, even though the neighboring product codes also use a per-square-centimeter unit.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4308PPRRVU2026_Oct_nonQPP.csv, line 18,395 (RVU26D)
Geographic factors for Hawaii, GuamGPCI2026.csv, line 46 (RVU26D)

Open CMS sourceHow we calculate rates

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