Billing code 21552: Soft-tissue excisionMedicare rate & RVUs in Illinois

Report this service for complete removal of a subcutaneous neck or anterior chest soft-tissue lesion measuring at least 3 cm.

CMS RVU26DEffective Oct 1, 20264 payment localities4.6K Medicare services in 2024

CMS doesn’t publish an office rate for 21552 in Illinois.

—Office (non-facility)
$442.82–$496.40Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 21552 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Illinois
  2. What 21552 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 21552 covers

An otolaryngologist, general surgeon, or plastic surgeon may remove a palpable lipoma, cyst, or other soft-tissue mass in the subcutaneous layer of the neck or anterior chest. The operation removes the lesion rather than taking only a diagnostic sample. It may occur in an office procedure room or operating room depending on the lesion and patient’s needs.

Choose 21552 when the lesion is subcutaneous and measures at least 3 cm; its depth and size distinguish it from codes for smaller superficial lesions or deeper tumors. Document the site, size, tissue plane, and excision performed. This major-surgery service includes the day-before preoperative visit and 90 days of related postoperative care. For multiple procedures in one session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. Modifier 50 is inappropriate for this code’s descriptor and anatomy. An assistant at surgery may be paid; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 21552 pays more and less in Illinois

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

21552 office and facility rates by payment locality
Payment localityOfficeFacility
ChicagoUnavailable$496.40
East St. LouisUnavailable$466.59
Rest Of IllinoisUnavailable$442.82
Suburban ChicagoUnavailable$473.89

How the 21552 rate is calculated

Each of 21552’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 21552

RVUs × geographic indexes × conversion factor

Work6.33

6.33 RVUs× 1.000 GPCI

Practice expense5.02

5.02 RVUs× 1.000 GPCI

Malpractice1.50

1.50 RVUs× 1.000 GPCI

Adjusted RVUs

12.8500

Conversion factor

$33.4009

Medicare rate

$429.20

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 21552

21552 has a 90-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 21552

Soft-tissue excision

RuleCMS valueWhat it means
Global period090Major surgery: the day before, the day of, and 90 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)2Paid.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.69/0.21Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 21552

Soft-tissue excision

90-day global period ends

Dec 30, 2026

Covers Sep 30, 2026 through Dec 30, 2026 (92 days, including the day before surgery).

Visit on Oct 31, 2026

Day 30 of the 90-day post-op period: related follow-up care is included in the surgical payment.

  • 24Unrelated E/M visit by the same physician
  • 79Unrelated procedure (starts its own global period)
  • 58Staged, more extensive, or therapy procedure that was planned
  • 78Unplanned return to the operating room for a related complication
SurgeryVisit
Sep 23, 2026Jan 10, 2027

Pre-op dayGlobal period

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

21552 without 51 · national facility

$429.20

Soft-tissue excision

21552-51 · Second procedure: 50%

$214.60

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

21552 compared with similar codes

Compare codes · National

5 codes, side by side

  • 21552

    Soft-tissue excision6.33 wRVU

    Not priced

  • 21555

    Mass excision3.86 wRVU

    $462.60

  • 21554

    Tumor excision10.85 wRVU

    Not priced

  • 21556

    Tumor excision7.47 wRVU

    Not priced

  • 21550

    Soft-tissue biopsy2.06 wRVU

    $271.88

How to choose

21555Mass excision
Both concern superficial neck or anterior chest lesions. The size threshold is the distinction: 21552 is for lesions at least 3 cm; 21555 is for lesions under 3 cm.
21554Tumor excision
This code is for a deep neck tumor measuring 5 cm or larger. Choose 21552 for a subcutaneous lesion measuring at least 3 cm.
21556Tumor excision
This code is for a deep neck tumor under 5 cm. Use 21552 when the lesion is subcutaneous and at least 3 cm.
21550Soft-tissue biopsy
21550 represents a soft-tissue biopsy for diagnosis; 21552 represents excision of the qualifying subcutaneous lesion.

21552 billing questions

How is 21552 distinguished from 21555?

Both describe removal of a subcutaneous neck or anterior chest lesion. Use 21552 for a lesion measuring 3 cm or larger and 21555 for one under 3 cm.

When should a deep-tumor code be considered instead?

Use the deep-tumor code family when the operative documentation places the mass beneath the subcutaneous tissue, such as in a deeper soft-tissue plane. Select within that family by its size threshold.

Does 21552 include postoperative visits?

Yes. The 90-day global period includes the day-before preoperative visit and 90 days of related postoperative care.

Can modifier 50 be used for bilateral lesions?

No. Modifier 50 is inappropriate for this code’s descriptor and anatomy.

How are other procedures in the same session paid?

The highest-valued procedure is paid in full; other procedures performed in that session are subject to the standard multiple-procedure 50% reduction.

May an assistant or co-surgeon be reported?

An assistant at surgery may be paid. Co-surgeons and team surgery are not permitted for this code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 21552PPRRVU2026_Oct_nonQPP.csv, line 2,002 (RVU26D)

Open CMS sourceHow we calculate rates

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