Billing code 65756: Corneal transplantMedicare rate & RVUs in Illinois

Reports transplantation of donor corneal endothelial tissue to treat endothelial dysfunction while retaining the recipient cornea’s anterior layers.

CMS RVU26DEffective Oct 1, 20264 payment localities22.3K Medicare services in 2024

CMS doesn’t publish an office rate for 65756 in Illinois.

—Office (non-facility)
$981.55–$1,054.17Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 65756 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Illinois
  2. What 65756 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 65756 covers

An ophthalmic surgeon uses this code for endothelial keratoplasty, replacing the diseased inner corneal layer with donor tissue. Common clinical settings include endothelial failure associated with Fuchs dystrophy or pseudophakic bullous keratopathy. Techniques such as DSAEK and DMEK are examples of endothelial graft procedures. The service is generally performed in an operating room or ambulatory surgery center, with related postoperative care managed by the surgeon.

The operative report should establish that the transplanted tissue is an endothelial graft and identify the treated eye and surgical technique. CMS assigns a 90-day global period, including the day-before preoperative visit and 90 days of related postoperative care. For multiple procedures in the same session, the highest-valued procedure is paid in full and others at 50%. Bilateral reporting with modifier 50 is paid at 150%. Assistant-at-surgery services may be paid; co-surgeon payment requires supporting documentation, and team surgery is not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 65756 pays more and less in Illinois

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

65756 office and facility rates by payment locality
Payment localityOfficeFacility
ChicagoUnavailable$1,054.17
East St. LouisUnavailable$1,004.08
Rest Of IllinoisUnavailable$981.55
Suburban ChicagoUnavailable$1,040.08

How the 65756 rate is calculated

Each of 65756’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 65756

RVUs × geographic indexes × conversion factor

Work16.42

16.42 RVUs× 1.000 GPCI

Practice expense11.96

11.96 RVUs× 1.000 GPCI

Malpractice1.31

1.31 RVUs× 1.000 GPCI

Adjusted RVUs

29.6900

Conversion factor

$33.4009

Medicare rate

$991.67

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 65756

65756 has a 90-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 65756

Corneal transplant

RuleCMS valueWhat it means
Global period090Major surgery: the day before, the day of, and 90 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)1Bilateral with modifier 50 pays 150% of the fee schedule amount.
Assistant at surgery (80/81/82/AS)2Paid.
Co-surgeons (62)1Permitted with supporting documentation.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.70/0.20Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 65756

Corneal transplant

90-day global period ends

Dec 30, 2026

Covers Sep 30, 2026 through Dec 30, 2026 (92 days, including the day before surgery).

Visit on Oct 31, 2026

Day 30 of the 90-day post-op period: related follow-up care is included in the surgical payment.

  • 24Unrelated E/M visit by the same physician
  • 79Unrelated procedure (starts its own global period)
  • 58Staged, more extensive, or therapy procedure that was planned
  • 78Unplanned return to the operating room for a related complication
SurgeryVisit
Sep 23, 2026Jan 10, 2027

Pre-op dayGlobal period

What modifiers do to the payment

Modifier 50 · payment effect

With and without the modifier

65756 without 50 · national facility

$991.67

Corneal transplant

65756-50 · Bilateral: 150%

$1,487.51

Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).

When to use modifier 50

65756 compared with similar codes

Compare codes · National

4 codes, side by side

  • 65756

    Corneal transplant16.42 wRVU

    Not priced

  • 65710

    Corneal transplant14.09 wRVU

    Not priced

  • 65730

    Corneal transplant15.94 wRVU

    Not priced

  • 65757

    Not on the physician fee schedule0 wRVU

    Not priced

How to choose

65710Corneal transplant
Use 65710 for a lamellar graft involving a different corneal layer. Use 65756 when the transplanted tissue is an endothelial graft.
65730Corneal transplant
Use 65730 for a penetrating, full-thickness transplant. This code describes endothelial keratoplasty rather than replacement of the full corneal thickness.
65757Prep corneal endo allograft
65757 represents preparation of donor endothelial tissue before transplantation; 65756 represents the transplant procedure itself.

65756 billing questions

How is this different from a penetrating corneal transplant?

This code is for replacing the endothelial layer with donor tissue. A penetrating transplant replaces the full thickness of the cornea.

Can donor tissue preparation be reported separately?

billing code 65757 describes preparation of donor endothelial tissue before transplantation. Report it when that preparation service is performed and documented with the graft procedure.

Does the global period include routine postoperative visits?

Yes. The 90-day global period includes the day-before preoperative visit and 90 days of related postoperative care.

How is a bilateral transplant reported under the CMS rule?

For bilateral surgery, CMS specifies modifier 50 and payment at 150%.

Can an assistant or co-surgeon be reported?

Assistant-at-surgery services may be paid. Co-surgeon payment requires supporting documentation.

How are other procedures in the same session paid?

The highest-valued procedure is paid in full, and other procedures subject to the multiple procedure reduction are paid at 50%.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 65756PPRRVU2026_Oct_nonQPP.csv, line 7,331 (RVU26D)

Open CMS sourceHow we calculate rates

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