Billing code 77750: Radioactive solutionMedicare rate & RVUs in Illinois

Reports treatment delivery by infusing or instilling a radioactive solution at a treatment site, rather than applying a sealed brachytherapy source.

CMS RVU26DEffective Oct 1, 20264 payment localities566 Medicare services in 2024

Medicare pays $380.89–$409.35 for 77750 in the office in Illinois, from Rest Of Illinois to Suburban Chicago. Which amount applies depends on the service address.

$380.89–$409.35Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 77750 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Illinois
  2. What 77750 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 77750 covers

billing code 77750 represents delivery of a radioactive solution by infusion or instillation to a treatment site. In radiation oncology, a radiation oncologist directs the treatment; instilling a radionuclide solution into a body cavity is a representative use. The defining feature is solution-based delivery, not placement of a sealed source or the complexity of an intracavitary applicator.

Document the radionuclide solution, route and treatment site, and the service performed so the record supports this delivery method. CMS assigns a 90-day major-surgery global period: the day-before preoperative visit and 90 days of related postoperative care are included. The service may be billed globally or split into modifier 26 for interpretation and modifier TC for equipment and staff. An assistant at surgery is paid only when medical necessity is documented; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 77750 pays more and less in Illinois

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

4 payment localities

$380.89 to $409.35

$380.89$395.12$409.35
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
77750 office and facility rates by payment locality
Payment localityOfficeFacility
Chicago$408.97Unavailable
East St. Louis$386.37Unavailable
Rest Of Illinois$380.89Unavailable
Suburban Chicago$409.35Unavailable

How the 77750 rate is calculated

Each of 77750’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 77750

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 4.88Practice expense 6.70Malpractice 0.26

11.8400 adjusted RVUs×$33.4009 conversion factor=$395.47

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 77750

77750 has a 90-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 77750

Radioactive solution

RuleCMS valueWhat it means
Global period090Major surgery: the day before, the day of, and 90 days after are included.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.
Split (54/55/56)0.00/0.00/0.00Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 77750

Radioactive solution

90-day global period ends

Dec 30, 2026

Covers Sep 30, 2026 through Dec 30, 2026 (92 days, including the day before surgery).

Visit on Oct 31, 2026

Day 30 of the 90-day post-op period: related follow-up care is included in the surgical payment.

  • 24 Unrelated E/M visit by the same physician
  • 79 Unrelated procedure (starts its own global period)
  • 58 Staged, more extensive, or therapy procedure that was planned
  • 78 Unplanned return to the operating room for a related complication
SurgeryVisit
Sep 23, 2026Jan 10, 2027

Pre-op dayGlobal period

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

77750 without 26 · national office

$395.47

Radioactive solution

77750-26 · Professional component

$262.53

Pays only the interpretation and report.

When to use modifier 26

77750 compared with similar codes

Compare codes

77750 vs 77761 vs 77778 vs 77789: national Medicare rates

Swap in your local Medicare rate.

  • 77750
    Radioactive solution · 4.88 wRVU
    $395.47
  • 77761
    Intracavitary brachytherapy · 3.75 wRVU
    $424.19+$28.72
  • 77778
    Interstitial brachytherapy · 8.56 wRVU
    $932.89+$537.42
  • 77789
    Surface brachytherapy · 1.11 wRVU
    $132.94−$262.53

How to choose

77761Intracavitary brachytherapy
Choose 77750 for infusion or instillation of a radioactive solution. Choose 77761 when the treatment is intracavitary radiation application using a source or applicator.
77778Interstitial brachytherapy
77750 describes solution delivery; 77778 describes interstitial radiation application. The method of delivery distinguishes the codes.
77789Surface brachytherapy
77789 is for surface radionuclide application. It is not the solution infusion or instillation service represented by 77750.

77750 billing questions

How does 77750 differ from an intracavitary radiation application code?

Use 77750 for delivery of a radioactive solution by infusion or instillation. Intracavitary application codes describe a different delivery method involving an intracavitary radiation source or applicator.

Can the professional and technical portions be billed separately?

Yes. Modifier 26 identifies the professional interpretation, and modifier TC identifies the technical portion; without either modifier, the claim represents the global service.

What care is included in the global period?

The 90-day global period includes the day-before preoperative visit and 90 days of related postoperative care.

What documentation supports reporting 77750?

Record the radioactive solution, the route and treatment site, and the infusion or instillation performed. The documentation should distinguish solution delivery from application of a sealed source.

Can an assistant or another surgeon be reported?

Assistant-at-surgery payment requires documentation of medical necessity. Co-surgeons and team surgery are not permitted for this code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 77750PPRRVU2026_Oct_nonQPP.csv, line 9,142 (RVU26D)

Open CMS sourceHow we calculate rates

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