$139.48
Choose 88348 for ultrastructural examination by electron microscopy; choose 88346 for immunofluorescence examination using the first antibody stain.
On this page
CMS RVU26D · Effective 2026-10-01
88348 Electron microscopy Medicare reimbursement rates in Minnesota
Reports ultrastructural examination of tissue, such as a kidney biopsy, when electron microscopy is needed to evaluate a diagnostic question. Compare 88348 office and facility rates across CMS payment localities in Minnesota.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for 88348 in Minnesota?
Minnesota has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$487.47
1 of 1 localities have a supported rate.
Payment area: Minnesota
One mapped payment locality.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Pathology
About 88348: Diagnostic tissue electron microscopy
Reports ultrastructural examination of tissue, such as a kidney biopsy, when electron microscopy is needed to evaluate a diagnostic question.
A pathology laboratory prepares tissue for examination at ultrastructural resolution, typically by embedding it, cutting very thin sections, and viewing them with an electron microscope. A pathologist interprets the findings. A familiar use is evaluating a kidney biopsy for changes in glomerular basement membranes, deposits, or other features that help characterize renal disease. The service may also be used for other tissue when the diagnostic question requires ultrastructural detail.
Report 88348 for the diagnostic electron microscopy service, not simply because a specimen was submitted for routine microscopic review. The pathology documentation should identify the tissue examined, the reason for the study, and the electron-microscopic findings and interpretation. CMS recognizes a professional component for the interpretation, reported with modifier 26, and a technical component for equipment and staff, reported with modifier TC. Without either modifier, the code represents the global service. The professional and technical components are separately priced when billed with their respective modifiers.
CMS billing rules for 88348
- Professional and technical components
- Diagnostic test with a professional component (modifier 26, interpretation) and a technical component (modifier TC, equipment and staff); billing without a modifier is the global service.
Where the value comes from
- Work RVU1.47 · 10%
- Practice expense (office) RVU12.72 · 89%
- Malpractice RVU0.12 · 1%
13.8K
Medicare services in 2024 · #1300 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
88348 compared with similar codes
Office rates for Minnesota, from the same CMS release.
$141.87
88348 evaluates tissue ultrastructure by electron microscopy. 88355 is morphometric analysis of skeletal muscle, not an electron-microscopy service.
$112.27
88348 is an ultrastructural microscopy service. 88342 reports immunohistochemical staining and examination for the first antibody.
Compare 88348 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Minnesota →
Office / nonfacility
$487.47
Facility
Unavailable
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 88348 in Minnesota.
PPRRVU2026_Oct_nonQPP.csv
11,260
- Code
- 88348
- Physician work
- 1.47
- Practice expense
- 12.72
- Malpractice
- 0.12
GPCI2026.csv
66
- Locality
- Minnesota
- Physician work
- 1.000
- Practice expense
- 1.029
- Malpractice
- 0.296
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 1.47 | × 1.000 | 1.4700 |
| Practice expense | 12.72 | × 1.029 | 13.0889 |
| Malpractice | 0.12 | × 0.296 | 0.0355 |
| Total RVUs | 14.5944 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Minnesota$487.47
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 1.47 | 1 |
| Practice expense | 12.72 | 1.029 |
| Malpractice | 0.12 | 0.296 |
(1.47 × 1 + 12.72 × 1.029 + 0.12 × 0.296) × $33.4009 = $487.47
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
88348 billing questions
When is 88348 appropriate for a kidney biopsy?
Use it when the biopsy workup includes diagnostic ultrastructural examination to address a renal pathology question. Routine tissue microscopy or immunofluorescence alone is not this service.
How does 88348 differ from 88346?
88348 reports electron-microscopic examination of ultrastructure. 88346 reports immunofluorescence staining and examination for the first antibody.
Can the professional and technical portions be billed separately?
Yes. Report modifier 26 for the professional interpretation and modifier TC for the technical work, including equipment and staff. Without either modifier, 88348 represents the global service.
What documentation supports reporting 88348?
Document the tissue source, the diagnostic reason for electron microscopy, and the ultrastructural findings and interpretation. The record should support that electron microscopy was performed, rather than only routine histology or antibody staining.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
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11,25888346,26,Imfluor 1st 1antb stain px,A,,0.72,0.27,,0.27,,0.01,1.00,1.00,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,25988346,TC,Imfluor 1st 1antb stain px,A,,0.00,3.08,,3.08,NA,0.02,3.10,3.10,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,26088348,,Electron microscopy dx,A,,1.47,12.72,,12.72,NA,0.12,14.31,14.31,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,26188348,26,Electron microscopy dx,A,,1.47,0.66,,0.66,,0.03,2.16,2.16,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,26288348,TC,Electron microscopy dx,A,,0.00,12.06,,12.06,NA,0.09,12.15,12.15,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,26388350,,Imfluor ea addl 1antb stn px,A,,0.58,2.60,,2.60,NA,0.02,3.20,3.20,1,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
6314212,MA,99,REST OF MASSACHUSETTS,1.016,1.053,0.797
6408202,MI,01,DETROIT,1.000,0.965,1.686
6508202,MI,99,REST OF MICHIGAN,1.000,0.913,1.129
6606202,MN,00,MINNESOTA,1.000,1.029,0.296
6707302,MS,00,MISSISSIPPI,1.000,0.861,0.739
6805302,MO,02,METROPOLITAN KANSAS CITY,1.000,0.939,0.977
6905302,MO,01,METROPOLITAN ST. LOUIS,1.000,0.952,1.002