$143.70–$153.09
This is an application procedure for qualifying trunk or extremity sites; Q4378 reports Renew FT Matrix supplied with the primary procedure.
On this page
CMS RVU26D · Effective 2026-10-01
Q4378 Wound matrix Medicare reimbursement rates in Missouri
Reports each square centimeter of Renew FT Matrix supplied with a primary wound procedure that applies a matrix to a treated wound bed. Compare Q4378 office and facility rates across CMS payment localities in Missouri.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for Q4378 in Missouri?
Missouri has 3 payment localities in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the 3 payment areas shown below, using the same CMS release.
Office / nonfacility
$109.70–$121.15
3 of 3 localities have a supported rate.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Where Q4378 pays more and less in Missouri
3 payment localities
$109.70 to $121.15
Wound care products
About Q4378: Renew FT wound matrix, per square centimeter
Reports each square centimeter of Renew FT Matrix supplied with a primary wound procedure that applies a matrix to a treated wound bed.
Q4378 identifies the Renew FT Matrix product used in wound care. A clinician applies the matrix to a prepared wound bed as part of treatment; the product line represents the material, not the work of preparing the site or applying it. It is reported by the area of product supplied, rather than by the number of wounds or applications. The related application service is generally reported separately.
Report the product only with a primary procedure, using documentation that identifies Renew FT Matrix and supports the square-centimeter quantity supplied. CMS treats Q4378 as an add-on, paid within the primary procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation. The product code does not replace the application procedure code, and its units should reflect the area documented for the product used.
CMS billing rules for Q4378
- Global period
- Add-on code: billed only together with a primary procedure and paid within that procedure's global period.
- Professional and technical components
- Technical-component-only code: a separate code covers interpretation.
Where the value comes from
- Work RVU0.00 · 0%
- Practice expense (office) RVU3.81 · 100%
- Malpractice RVU0.00 · 0%
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4378 compared with similar codes
Office rates for Missouri, from the same CMS release.
$147.15–$155.82
This application procedure covers qualifying head, neck, hand, foot, or genital sites. Q4378 identifies the product, not the application or anatomical site.
$109.70–$121.15
Q4377 identifies Trigraft FT, whereas Q4378 identifies Renew FT Matrix. Report the product actually supplied.
$109.70–$121.15
Q4379 identifies Amniodefend FT, not Renew FT Matrix. The product-specific code follows the material used.
Compare Q4378 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
3 of 3 payment localities
Metropolitan Kansas City →
Office / nonfacility
$119.49
Facility
Unavailable
Metropolitan St. Louis →
Office / nonfacility
$121.15
Facility
Unavailable
Rest Of Missouri →
Office / nonfacility
$109.70
Facility
Unavailable
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Q4378 billing questions
Is Q4378 the wound application procedure?
No. It identifies the Renew FT Matrix product by square centimeter. Report the wound application procedure separately when performed.
What should support the units?
Document the product used and the square-centimeter area supplied. Do not base units on the number of wounds alone.
Can Q4378 be reported by itself?
No. CMS identifies it as an add-on code that must be billed with a primary procedure.
How does the global-period rule affect this code?
Payment for Q4378 is within the primary procedure’s global period. It is not separately paid outside that procedure’s global period.
Is there a separate professional interpretation component?
CMS classifies Q4378 as technical-component-only, with interpretation covered by a separate code.
How is Q4378 different from Q4377 or Q4379?
Those codes identify Trigraft FT and Amniodefend FT, respectively. Select the code matching the product actually supplied; their product quantities are not interchangeable.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
18,461Q4375,,Duograft ac per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,462Q4376,,Duograft aa per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,463Q4377,,Trigraft ft per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,464Q4378,,Renew ft matrix per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,465Q4379,,Amniodefend ft per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,466Q4380,,Advograft one per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,467Q4382,,Advograft dual per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00