CPT code 95165: Allergy extract preparation2026 Medicare rate & RVUs in Nebraska

Physician-supervised preparation of allergen extract in multidose vials for allergy shots, reported by doses prepared rather than injections administered.

CMS RVU26DEffective Oct 1, 20261 payment locality5.9M Medicare services in 2024

Medicare pays $16.00 for 95165 in the office in Nebraska (Nebraska). Which amount applies depends on the service address.

$16.00Office (non-facility)
$2.44Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 95165 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Nebraska
  2. What 95165 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 95165 covers

This service covers an allergist's selection of allergens and concentrations and supervision of custom extract preparation in multidose vials. Allergy and immunology practices typically prepare extracts after testing and clinical history identify relevant sensitivities to pollens, molds, dust mites, or animal dander. The preparing practice may administer the shots or send the extract to another office, such as a primary care clinic. Preparation does not include administering an injection.

Report units based on doses prepared, not shots given. For Medicare, one dose is a 1 mL aliquot from a multidose vial, regardless of the volume injected at a visit; a 10 mL vial therefore supports 10 units. The record should identify each vial's allergens, concentration, volume, preparation date, and supervising physician. When administered, injections are reported separately with 95115 for one injection or 95117 for two or more. CMS assigns substantially more practice-expense RVUs to this service in the office than in a facility.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

95165 in Nebraska

95165 office and facility rates by payment locality
Payment localityOfficeFacility
Nebraska$16.00$2.44

How the 95165 rate is calculated

Each of 95165’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 95165

RVUs × geographic indexes × conversion factor

Work0.06

0.06 RVUs× 1.000 GPCI

Practice expense0.45

0.45 RVUs× 1.000 GPCI

Malpractice0.01

0.01 RVUs× 1.000 GPCI

Adjusted RVUs

0.5200

Conversion factor

$33.4009

Medicare rate

$17.37

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 95165

95165 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · 95165

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

$17.37

Non-facility (office)
$17.37
Facility
$2.67

Higher because the practice carries its own overhead.

95165 compared with similar codes

Compare codes · National

5 codes, side by side

  • 95165

    Allergy extract preparation0.06 wRVU

    $17.37

  • 95144

    Allergen preparation0.06 wRVU

    $21.04+$3.67

  • 95146

    Venom antigen preparation0.06 wRVU

    $62.46+$45.09

  • 95117

    Allergy shots0 wRVU

    $12.36−$5.01

  • 95125

    Not on the physician fee schedule0 wRVU

    Not priced

How to choose

95144Allergen preparation
95144 is for single-dose vials. 95165 is for multidose vials, with Medicare units based on 1 mL aliquots from each vial.
95146Venom antigen preparation
95146 covers preparation of two stinging-insect venoms. 95165 covers multidose extracts for non-venom allergens, such as pollens or dust mites.
95117Allergy shots
95117 reports administering two or more allergy shots at a visit. 95165 reports preparation of the extract, whether or not an injection occurs that day.
95125Immunotherapy 2/> injections
95125 combines extract provision with two or more injections and is not recognized by Medicare. When both services are furnished for non-venom immunotherapy, report the appropriate 95117 and 95165 units separately.

95165 billing questions

How many units should be billed for a multidose vial?

Medicare counts one unit per 1 mL aliquot from the vial: a 5 mL vial supports 5 units, and a 10 mL vial supports 10. The volume injected at each visit does not change that count.

Can 95165 be billed on the same day as an injection code?

Yes, when extract preparation and administration both occur that day. Report preparation with 95165 and administration with 95115 for one injection or 95117 for two or more.

What if the allergist prepares the extract but another physician gives the shots?

The preparing practice reports 95165 for the doses prepared. The administering practice reports 95115 or 95117 for injections it gives, rather than reporting 95165 for extract it did not prepare.

Should the complete-service codes 95120 through 95134 be used for Medicare patients?

No. Medicare does not recognize those combined injection-and-extract codes. Report the appropriate injection and antigen preparation codes separately when both services are furnished.

When is 95144 used instead of 95165?

Use 95144 for extract prepared in single-dose vials. Use 95165 for extract prepared in multidose vials, with units based on the doses the vials contain.

Can an E/M visit be billed on an injection day?

A separately identifiable evaluation of new symptoms may be reported when it goes beyond routine injection screening and is documented. Append modifier 25 to the E/M code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 95165PPRRVU2026_Oct_nonQPP.csv, line 12,487 (RVU26D)
Geographic factors for NebraskaGPCI2026.csv, line 72 (RVU26D)

Open CMS sourceHow we calculate rates

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