HCPCS code Q4388: Wound product2026 Medicare rate & RVUs in Nevada

Q4388 identifies Neothelium 4L wound product by square centimeter when supplied for application during a wound procedure.

CMS RVU26DEffective Oct 1, 20261 payment locality

Medicare pays $127.38 for Q4388 in the office in Nevada (Nevada**). Which amount applies depends on the service address.

$127.38Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4388 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Nevada
  2. What Q4388 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4388 covers

Q4388 represents the Neothelium 4L product supplied for wound treatment, measured by square centimeter. It is typically associated with application to a wound, such as a chronic diabetic foot ulcer or venous leg ulcer, by a wound-care clinician, podiatrist, or surgeon in an office or hospital outpatient setting. The code identifies the product, not the clinical assessment or wound-preparation work.

Report the number of square centimeters represented by the product supplied, and retain documentation identifying the product, wound site, treated area, and amount used. Q4388 is an add-on code: report it only with a primary procedure, and its payment is within that procedure’s global period. CMS classifies it as technical-component-only; a separate code covers interpretation. Neothelium 4L is distinct from other Neothelium product variants, so use the product identification and applicable code rather than selecting by brand name alone.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Q4388 in Nevada**

Q4388 office and facility rates by payment locality
Payment localityOfficeFacility
Nevada**$127.38Unavailable

How the Q4388 rate is calculated

Each of Q4388’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4388

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4388

The CMS indicators that decide how Q4388 is paid alongside other services.

CMS payment indicators · Q4388

Wound product

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4388 compared with similar codes

Compare codes · National

4 codes, side by side

  • Q4388

    Wound product0 wRVU

    $127.26

  • Q4387

    Skin substitute0 wRVU

    $127.26+$0.00

  • Q4389

    Wound matrix0 wRVU

    $127.26+$0.00

  • 15271

    Skin substitute graft1.46 wRVU

    $157.99+$30.73

How to choose

Q4387Skin substitute
Q4387 identifies Neothelium FT; Q4388 identifies Neothelium 4L. Match the code to the product variant supplied.
Q4389Wound matrix
Q4389 identifies Neothelium 4L+, not Neothelium 4L. The shared brand does not make the product codes interchangeable.
15271Skin substitute graft
15271 reports the application procedure for qualifying wounds on the trunk, arms, or legs. Q4388 identifies the Neothelium 4L product supplied with a primary procedure.

Q4388 billing questions

Can Q4388 be reported by itself?

No. CMS identifies it as an add-on code, so it must be reported with a primary procedure.

How are units determined?

The descriptor is per square centimeter. Document the wound area treated and the amount of Neothelium 4L supplied.

How does Q4388 differ from Q4387?

Both identify Neothelium products, but Q4388 is the 4L variant and Q4387 is Neothelium FT. Select the code matching the product supplied.

How does Q4388 differ from Q4389?

Q4389 identifies Neothelium 4L+, a separately coded variant. Do not substitute it for Q4388 based only on the shared Neothelium name.

Does Q4388 include interpretation?

No. CMS classifies Q4388 as technical-component-only, with interpretation represented by a separate code.

What documentation supports Q4388?

Record the product as Neothelium 4L, the wound location and treated area, and the quantity supplied in square centimeters.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4388PPRRVU2026_Oct_nonQPP.csv, line 18,473 (RVU26D)
Geographic factors for Nevada**GPCI2026.csv, line 73 (RVU26D)

Open CMS sourceHow we calculate rates

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