Billing code 64615: Migraine chemodenervationMedicare rate & RVUs in Ohio

Reports bilateral medication injections into head and neck muscles for chronic migraine treatment, commonly performed by a neurologist or headache specialist.

CMS RVU26DEffective Oct 1, 20261 payment locality191.4K Medicare services in 2024

Medicare pays $150.52 for 64615 in the office in Ohio (Ohio). Which amount applies depends on the service address.

$150.52Office (non-facility)
$106.92Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 64615 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Ohio
  2. What 64615 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 64615 covers

This service covers medication injections into muscles on both sides of the head and neck, commonly using onabotulinumtoxinA for chronic migraine. A neurologist or headache specialist may inject muscles such as the frontalis, temporalis, occipital, cervical paraspinal, and trapezius muscles in an office or outpatient facility. The service represents the overall bilateral treatment, rather than a separate charge for each injection site.

Select the code for bilateral chemodenervation of the covered head and neck muscles, and document the indication, treated sites, laterality, and dose. Report the bilateral code once for the session; modifier 50 does not increase its payment. When other procedures are performed in the same session, the highest-valued procedure is paid in full and the others are subject to the standard 50% multiple-procedure reduction. Related postoperative visits during the 10-day global period are included. Assistant-at-surgery payment is restricted, and co-surgeons and team surgery are not permitted. The toxin may be reported separately under its applicable drug code when supplied by the practice.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

64615 in Ohio

64615 office and facility rates by payment locality
Payment localityOfficeFacility
Ohio$150.52$106.92

How the 64615 rate is calculated

Each of 64615’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 64615

RVUs × geographic indexes × conversion factor

Work1.80

1.80 RVUs× 1.000 GPCI

Practice expense2.28

2.28 RVUs× 1.000 GPCI

Malpractice0.62

0.62 RVUs× 1.000 GPCI

Adjusted RVUs

4.7000

Conversion factor

$33.4009

Medicare rate

$156.98

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 64615

64615 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 64615

Migraine chemodenervation

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)2Already bilateral by definition: paid once at 100%.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 64615

Migraine chemodenervation

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

64615 without 51 · national office

$156.98

Migraine chemodenervation

64615-51 · Second procedure: 50%

$78.49

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

64615 compared with similar codes

Compare codes · National

4 codes, side by side

  • 64615

    Migraine chemodenervation1.8 wRVU

    $156.98

  • 64612

    Facial chemodenervation1.37 wRVU

    $141.62−$15.36

  • 64616

    Neck chemodenervation1.49 wRVU

    $143.62−$13.36

  • 64642

    Chemodenervation1.61 wRVU

    $163.33+$6.35

How to choose

64612Facial chemodenervation
Use 64615 for the bilateral head and neck muscle treatment associated with chronic migraine. Code 64612 addresses facial-muscle chemodenervation for a different indication and is not the migraine service.
64616Neck chemodenervation
Code 64616 is for neck-muscle chemodenervation, typically for cervical dystonia. Code 64615 represents the bilateral head and neck treatment for migraine.
64642Chemodenervation
Code 64642 applies to chemodenervation of a limited number of muscles in one extremity; 64615 is for bilateral head and neck treatment.

64615 billing questions

Should modifier 50 be appended?

No. The code is already priced as bilateral, and modifier 50 does not increase payment.

Is the service reported per injection site or muscle?

Report the bilateral service once for the session, not once for each injection or treated muscle. Document the sites and dose.

Can the botulinum toxin drug be billed separately?

The practice may report the applicable drug code separately when it supplies the toxin. Keep documentation of the product and dose administered.

How does the 10-day global period affect follow-up visits?

Related postoperative visits during the 10 days after the procedure are included in the service.

What happens when another procedure is performed in the same session?

The highest-valued procedure is paid in full; other procedures in that session are subject to the standard 50% multiple-procedure reduction.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 64615PPRRVU2026_Oct_nonQPP.csv, line 7,170 (RVU26D)
Geographic factors for OhioGPCI2026.csv, line 85 (RVU26D)

Open CMS sourceHow we calculate rates

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