HCPCS Q4154: Wound matrixMedicare rate & RVUs in Ohio

Reports Biovance amniotic membrane used as a wound covering, with units based on the product amount and billing paired with a primary application procedure.

CMS RVU26DEffective Oct 1, 20261 payment locality

Medicare pays $116.19 for Q4154 in the office in Ohio (Ohio). Which amount applies depends on the service address.

$116.19Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4154 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Ohio
  2. What Q4154 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4154 covers

Q4154 identifies Biovance, a dehydrated human amniotic membrane allograft used as a biologic covering in wound care. Wound-care clinicians and surgeons may apply it to cutaneous wounds, including diabetic foot or venous leg ulcers, in settings where wound treatment is performed. This code represents the product, measured in one-square-centimeter units; it is not the application procedure itself.

Report Q4154 with the primary procedure for applying the skin substitute, using the documented product amount and the appropriate application code for the wound site and area. The record should identify Biovance, the treated wound, and the amount used. CMS classifies Q4154 as an add-on: it is billed only with a primary procedure and paid within that procedure’s global period. It is technical-component-only; interpretation is represented by a separate code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Q4154 in Ohio

Q4154 office and facility rates by payment locality
Payment localityOfficeFacility
Ohio$116.19Unavailable

How the Q4154 rate is calculated

Each of Q4154’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4154

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4154

The CMS indicators that decide how Q4154 is paid alongside other services.

CMS payment indicators · Q4154

Wound matrix

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4154 compared with similar codes

Compare codes · National

4 codes, side by side

  • Q4154

    Wound matrix0 wRVU

    $127.26

  • 15271

    Skin substitute graft1.46 wRVU

    $157.99+$30.73

  • 15275

    Skin substitute1.78 wRVU

    $160.32+$33.06

  • Q4152

    Skin substitute0 wRVU

    $127.26+$0.00

How to choose

15271Skin substitute graft
15271 reports the primary application service for qualifying wounds on the trunk, arms, or legs; Q4154 identifies the Biovance product used with that service.
15275Skin substitute
15275 is a primary application procedure for qualifying wounds at specified special sites. Q4154 reports the Biovance product, not the site-specific application.
Q4152Skin substitute
Q4152 identifies Dermapure, while Q4154 identifies Biovance. Choose the product code that matches the wound covering actually used.

Q4154 billing questions

Is Q4154 the code for applying the wound covering?

No. Q4154 identifies the Biovance product per square centimeter. Report the appropriate primary skin-substitute application procedure separately.

What primary procedure is reported with Q4154?

Pair it with the application code selected for the wound site and total treated area. For example, 15271 is a primary application code for qualifying wounds on the trunk, arms, or legs.

How are Q4154 units determined?

Each unit represents one square centimeter of Biovance. Document the product amount used so the billed units can be supported.

Does Q4154 include interpretation?

No. CMS classifies it as technical-component-only; a separate code covers interpretation.

Can Q4154 be billed by itself?

No. CMS identifies it as an add-on that must be billed with a primary procedure and is paid within that procedure’s global period.

What documentation supports reporting Q4154?

Document that Biovance was used, the wound treated, and the product amount in square centimeters, along with the primary application procedure.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4154PPRRVU2026_Oct_nonQPP.csv, line 18,247 (RVU26D)
Geographic factors for OhioGPCI2026.csv, line 85 (RVU26D)

Open CMS sourceHow we calculate rates

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