$116.19
Q4221 identifies Amniowrap2, while Q4222 identifies ProgenaMatrix. Select the code matching the product supplied.
On this page
CMS RVU26D · Effective 2026-10-01
Q4222 Wound matrix Medicare reimbursement rates in Ohio
Q4222 reports ProgenaMatrix supplied for wound treatment, measured by square centimeter and billed with the associated primary procedure. Compare Q4222 office and facility rates across CMS payment localities in Ohio.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for Q4222 in Ohio?
Ohio has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$116.19
1 of 1 localities have a supported rate.
Payment area: Ohio
One mapped payment locality.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Wound care product
About Q4222: ProgenaMatrix wound product supply
Q4222 reports ProgenaMatrix supplied for wound treatment, measured by square centimeter and billed with the associated primary procedure.
Q4222 identifies ProgenaMatrix supplied for use as a wound matrix, with quantity measured in square centimeters. It represents the product, not the clinician’s wound evaluation or application work. A physician or other qualified practitioner may place the material during treatment of a skin wound in an office or facility setting, alongside the primary wound procedure.
Report Q4222 only with a primary procedure; CMS treats it as an add-on and pays it within that procedure’s global period. Document the product used and the square-centimeter quantity represented by the units billed. The code is technical-component-only, with a separate code covering interpretation. CMS assigns no physician-work RVU to Q4222; its RVUs reflect practice expense.
CMS billing rules for Q4222
- Global period
- Add-on code: billed only together with a primary procedure and paid within that procedure's global period.
- Professional and technical components
- Technical-component-only code: a separate code covers interpretation.
Where the value comes from
- Work RVU0.00 · 0%
- Practice expense (office) RVU3.81 · 100%
- Malpractice RVU0.00 · 0%
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4222 compared with similar codes
Office rates for Ohio, from the same CMS release.
$116.19
Q4223 identifies Dermabind SL optic rather than ProgenaMatrix. Both descriptors use square-centimeter units, but the product identity determines the code.
$116.19
Q4220 identifies Bellacell HD or SureDerm. Q4222 is specific to ProgenaMatrix, so the products are not distinguished by unit of measure alone.
Compare Q4222 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Ohio →
Office / nonfacility
$116.19
Facility
Unavailable
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for Q4222 in Ohio.
PPRRVU2026_Oct_nonQPP.csv
18,313
- Code
- Q4222
- Physician work
- 0.00
- Practice expense
- 3.81
- Malpractice
- 0.00
GPCI2026.csv
85
- Locality
- Ohio
- Physician work
- 1.000
- Practice expense
- 0.913
- Malpractice
- 1.008
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.00 | × 1.000 | 0.0000 |
| Practice expense | 3.81 | × 0.913 | 3.4785 |
| Malpractice | 0.00 | × 1.008 | 0.0000 |
| Total RVUs | 3.4785 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Ohio$116.19
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 0 | 1 |
| Practice expense | 3.81 | 0.913 |
| Malpractice | 0 | 1.008 |
(0 × 1 + 3.81 × 0.913 + 0 × 1.008) × $33.4009 = $116.19
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
Q4222 billing questions
Can Q4222 be billed by itself?
No. CMS identifies it as an add-on code that must be billed with a primary procedure and is paid within that procedure’s global period.
How should the units be determined?
Use the square-centimeter quantity of ProgenaMatrix represented by the units billed. Documentation should identify the product and quantity supplied.
Does Q4222 report the wound assessment or application work?
No. Q4222 identifies the product; the primary procedure reports the associated wound service.
Does Q4222 include interpretation?
No. CMS classifies Q4222 as technical-component-only; a separate code covers interpretation.
Can another per-square-centimeter wound product be reported as Q4222?
No. Q4222 is specific to ProgenaMatrix. Use the code for the product actually supplied, such as Q4221 or Q4223 when that named product is used.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
18,310Q4219,,Surgigraft dual per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,311Q4220,,"Bellacell hd, surederm sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,312Q4221,,Amniowrap2 per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,313Q4222,,"Progenamatrix, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,314Q4223,,Dermabind sl optic per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
18,315Q4224,,Hhf10-p per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,316Q4225,,"Amnio or derma tl, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
8213282,NY,99,REST OF NEW YORK,1.000,0.950,0.703
8311502,NC,00,NORTH CAROLINA,1.000,0.933,0.639
8403302,ND,01,NORTH DAKOTA**,1.000,1.000,0.406
8515202,OH,00,OHIO,1.000,0.913,1.008
8604312,OK,00,OKLAHOMA,1.000,0.893,0.777
8702302,OR,01,PORTLAND,1.016,1.111,0.744
8802302,OR,99,REST OF OREGON,1.000,0.996,0.703