Billing code 25065: Soft-tissue biopsyMedicare rate & RVUs in Oregon

Report this code when a surgeon obtains a diagnostic tissue sample from a superficial soft-tissue lesion of the forearm or wrist.

CMS RVU26DEffective Oct 1, 20262 payment localities398 Medicare services in 2024

Medicare pays $258.34–$281.18 for 25065 in the office in Oregon, from Rest Of Oregon to Portland. Which amount applies depends on the service address.

$258.34–$281.18Office (non-facility)
$142.90–$152.42Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 25065 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Oregon
  2. What 25065 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 25065 covers

This service obtains a tissue sample from a superficial soft-tissue lesion in the forearm or wrist for diagnostic examination. An orthopedic, hand, or other surgeon typically performs an open biopsy in an office procedure room, ambulatory surgery center, or hospital. The goal is to sample tissue for diagnosis, rather than remove the lesion as definitive treatment. The operative note should identify the site and describe the lesion’s depth and the tissue sampled.

Choose this code for a superficial biopsy; use the deep-tissue sibling when the sampled tissue is deep. Document the clinical reason for sampling, the approach, and the specimen sent for examination. Related postoperative visits during the 10-day global period are included. When multiple procedures occur in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. For bilateral procedures, modifier 50 is paid at 150%. Medicare does not pay an assistant at surgery for this service; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 25065 pays more and less in Oregon

25065 office and facility rates by payment locality
Payment localityOfficeFacility
Portland$281.18$152.42
Rest Of Oregon$258.34$142.90

How the 25065 rate is calculated

Each of 25065’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 25065

RVUs × geographic indexes × conversion factor

Work1.99

1.99 RVUs× 1.000 GPCI

Practice expense5.57

5.57 RVUs× 1.000 GPCI

Malpractice0.28

0.28 RVUs× 1.000 GPCI

Adjusted RVUs

7.8400

Conversion factor

$33.4009

Medicare rate

$261.86

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 25065

25065 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 25065

Soft-tissue biopsy

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)1Bilateral with modifier 50 pays 150% of the fee schedule amount.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 25065

Soft-tissue biopsy

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 50 · payment effect

With and without the modifier

25065 without 50 · national office

$261.86

Soft-tissue biopsy

25065-50 · Bilateral: 150%

$392.79

Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).

When to use modifier 50

25065 compared with similar codes

Compare codes · National

4 codes, side by side

  • 25065

    Soft-tissue biopsy1.99 wRVU

    $261.86

  • 25066

    Soft-tissue biopsy4.16 wRVU

    Not priced

  • 25075

    Forearm tumor excision3.86 wRVU

    $552.45+$290.59

  • 25076

    Forearm tumor excision6.57 wRVU

    Not priced

How to choose

25066Soft-tissue biopsy
Choose 25065 for a superficial sample and 25066 when the sampled forearm or wrist tissue is deep.
25075Forearm tumor excision
25075 describes excision of a superficial forearm lesion under 3 cm; 25065 describes biopsy for diagnostic sampling.
25076Forearm tumor excision
25076 describes excision of a deep forearm tumor under 3 cm. Use 25065 for superficial diagnostic sampling, not definitive tumor removal.

25065 billing questions

How does this code differ from 25066?

25065 is for a superficial soft-tissue biopsy of the forearm or wrist. Use 25066 when the sampled tissue is deep.

Should a biopsy code be used when the lesion is removed?

Use a biopsy code when tissue is sampled for diagnosis. When the lesion is excised, select the applicable excision code based on its depth and size.

Are the pathology examination and the biopsy bundled together?

This code represents obtaining the tissue sample. A separately performed pathology examination may be reported by the service that performs it.

How is a bilateral biopsy reported?

For bilateral procedures, report modifier 50; CMS pays the bilateral procedure at 150%.

Are postoperative visits included?

Related postoperative visits during the 10-day global period are included in the procedure.

Can an assistant or co-surgeon be reported?

Medicare does not pay an assistant at surgery for this code. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 25065PPRRVU2026_Oct_nonQPP.csv, line 2,378 (RVU26D)

Open CMS sourceHow we calculate rates

Did this answer your question about what 25065 pays in Oregon?

Tell us what you were actually trying to work out. We’ll answer you directly, or build the page that does.

Fee sheets

Put 25065 and the rest of your codes on one sheet

Build a fee sheet from your own code list at your locality, put your payer contracts beside Medicare, and see what changed each quarter.

Build my fee sheetOr price your code list free →