Billing code 41108: Oral biopsyMedicare rate & RVUs in Oregon

Report this service when a clinician biopsies a lesion or abnormal tissue arising from the floor of the mouth for diagnostic evaluation.

CMS RVU26DEffective Oct 1, 20262 payment localities966 Medicare services in 2024

Medicare pays $168.01–$183.65 for 41108 in the office in Oregon, from Rest Of Oregon to Portland. Which amount applies depends on the service address.

$168.01–$183.65Office (non-facility)
$82.51–$88.28Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 41108 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Oregon
  2. What 41108 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 41108 covers

A clinician removes a tissue sample from the floor of the mouth for diagnostic examination, often when an oral lesion or unexplained tissue change needs evaluation. Oral and maxillofacial surgeons, otolaryngologists, and other clinicians qualified to perform oral procedures may do the biopsy in an office or facility. The specimen is generally submitted for pathologic examination; the biopsy code describes the tissue-sampling procedure, not the pathology interpretation.

Select this code for a biopsy at the floor of the mouth, rather than a biopsy of the tongue or an excision of a lesion. The operative note should identify the sampled site and document that tissue was obtained for diagnosis. CMS assigns a 10-day global period, so related postoperative visits during that period are included. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. Do not use modifier 50 for this anatomy. CMS does not pay an assistant at surgery, and co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 41108 pays more and less in Oregon

41108 office and facility rates by payment locality
Payment localityOfficeFacility
Portland$183.65$88.28
Rest Of Oregon$168.01$82.51

How the 41108 rate is calculated

Each of 41108’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 41108

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.07Practice expense 3.87Malpractice 0.15

5.0900 adjusted RVUs×$33.4009 conversion factor=$170.01

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 41108

41108 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 41108

Oral biopsy

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 41108

Oral biopsy

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

41108 without 51 · national office

$170.01

Oral biopsy

41108-51 · Second procedure: 50%

$85.01

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

41108 compared with similar codes

Compare codes

41108 vs 41100 vs 41105 vs 41116 vs 40808: national Medicare rates

Swap in your local Medicare rate.

  • 41108
    Oral biopsy · 1.07 wRVU
    $170.01
  • 41100
    Tongue biopsy · 1.38 wRVU
    $188.05+$18.04
  • 41105
    Tongue biopsy · 1.43 wRVU
    $189.38+$19.37
  • 41116
    Oral lesion excision · 2.46 wRVU
    $335.35+$165.34
  • 40808
    Mouth biopsy · 1.02 wRVU
    $168.01−$2.00

How to choose

41100Tongue biopsy
41100 is for biopsy of the tongue. Choose 41108 when the biopsy site is the floor of the mouth.
41105Tongue biopsy
41105 also describes a tongue biopsy, not a floor-of-mouth biopsy. Base code selection on the documented anatomic site.
41116Oral lesion excision
41116 describes excision of a mouth lesion. Use 41108 when tissue is sampled for diagnosis rather than the lesion being excised.
40808Mouth biopsy
40808 is for biopsy of the vestibule of the mouth. It is not the code for tissue sampled from the floor of the mouth.

41108 billing questions

How is 41108 distinguished from a tongue biopsy?

Use 41108 when the sampled tissue is from the floor of the mouth. A biopsy of tongue tissue is coded according to the tongue site instead.

Can the pathology examination be reported separately?

The biopsy reports the clinician's tissue-sampling procedure. The pathologist's examination of the submitted specimen is a separate service when performed and reportable.

Is modifier 50 appropriate for bilateral floor-of-mouth biopsies?

No. CMS identifies bilateral adjustment as inappropriate for this code's descriptor and anatomy; do not append modifier 50.

What happens when another procedure is performed in the same session?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and the other procedures are paid at 50% when performed in the same session.

Are assistant surgeons or co-surgeons payable for 41108?

CMS does not pay an assistant at surgery for this service. Co-surgeons and team surgery are not permitted.

Are related postoperative visits included?

Yes. The code has a 10-day global period, which includes related postoperative visits during those 10 days.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 41108PPRRVU2026_Oct_nonQPP.csv, line 4,897 (RVU26D)

Open CMS sourceHow we calculate rates

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