Billing code 43252: Optical endomicroscopyMedicare rate & RVUs in Oregon

Reports optical endomicroscopic imaging performed during upper endoscopy to assess gastrointestinal mucosa at microscopic resolution in real time.

CMS RVU26DEffective Oct 1, 20262 payment localities4.5K Medicare services in 2024

Medicare pays $372.55–$405.49 for 43252 in the office in Oregon, from Rest Of Oregon to Portland. Which amount applies depends on the service address.

$372.55–$405.49Office (non-facility)
$146.33–$153.16Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 43252 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Oregon
  2. What 43252 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 43252 covers

During an upper gastrointestinal endoscopy, the endoscopist uses optical endomicroscopy to examine selected mucosal areas at microscopic resolution while viewing the tissue in real time. The technique can help characterize suspicious mucosal changes, including areas evaluated during Barrett esophagus surveillance. Gastroenterologists typically perform it in a hospital or ambulatory endoscopy setting as part of an EGD; it is not a tissue specimen examination by pathology.

Report this code when optical endomicroscopy is performed during the EGD, and document the areas examined and the imaging service. When related endoscopies are performed together, CMS applies endoscopy-family pricing rather than pricing each as an unrelated standalone procedure. The 0-day global period includes same-day preoperative and postoperative care. CMS does not pay an assistant at surgery for this service; co-surgeons and team surgery are not permitted. Modifier 50 is inappropriate for this code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 43252 pays more and less in Oregon

43252 office and facility rates by payment locality
Payment localityOfficeFacility
Portland$405.49$153.16
Rest Of Oregon$372.55$146.33

How the 43252 rate is calculated

Each of 43252’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 43252

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 2.89Practice expense 8.05Malpractice 0.35

11.2900 adjusted RVUs×$33.4009 conversion factor=$377.10

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 43252

The CMS indicators that decide how 43252 is paid alongside other services.

CMS payment indicators · 43252

Optical endomicroscopy

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures3Endoscopy family rules apply.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

43252 without 51 · national office

$377.10

Optical endomicroscopy

43252-51 · Second procedure: 50%

$188.55

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

43252 compared with similar codes

Compare codes

43252 vs 43239 vs 43259 vs 43254: national Medicare rates

Swap in your local Medicare rate.

  • 43252
    Optical endomicroscopy · 2.89 wRVU
    $377.10
  • 43239
    EGD with biopsy · 2.33 wRVU
    $418.85+$41.75
  • 43259
    Endoscopic ultrasound · 3.94 wRVU
    —
  • 43254
    Endoscopic resection · 4.75 wRVU
    —

How to choose

43239EGD with biopsy
Choose 43252 for optical endomicroscopic imaging; choose 43239 when the endoscopist obtains mucosal tissue for examination.
43259Endoscopic ultrasound
Code 43259 describes endoscopic ultrasound examination of the specified upper gastrointestinal anatomy. Code 43252 uses optical imaging to assess mucosa at microscopic resolution.
43254Endoscopic resection
Code 43254 describes endoscopic mucosal resection of a lesion. Code 43252 describes optical imaging, not lesion removal.

43252 billing questions

How is this different from EGD with biopsy, 43239?

This code describes real-time optical microscopic imaging of mucosa. Code 43239 describes obtaining tissue for histologic examination; imaging alone is not a biopsy.

Can biopsy or lesion treatment also be reported at the same session?

A separately performed biopsy or therapeutic service may have its own code, but document the distinct service and apply applicable coding and endoscopy-family pricing rules.

Should modifier 50 be appended?

No. CMS identifies bilateral adjustment as inapplicable and modifier 50 as inappropriate for this service.

Is an assistant surgeon payable?

CMS lists a statutory restriction on assistant-at-surgery payment for this code. Co-surgeons and team surgery are not permitted.

What same-day care is included in the global period?

The 0-day global period includes same-day preoperative and postoperative care.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 43252PPRRVU2026_Oct_nonQPP.csv, line 5,181 (RVU26D)

Open CMS sourceHow we calculate rates

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