Billing code 45378: ColonoscopyMedicare rate & RVUs in Oregon

Reports a diagnostic examination of the colon when the endoscopist inspects the colon without performing a separately described biopsy or therapeutic intervention.

CMS RVU26DEffective Oct 1, 20262 payment localities303.1K Medicare services in 2024

Medicare pays $373.00–$404.95 for 45378 in the office in Oregon, from Rest Of Oregon to Portland. Which amount applies depends on the service address.

$373.00–$404.95Office (non-facility)
$160.42–$167.83Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 45378 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Oregon
  2. What 45378 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 45378 covers

A gastroenterologist or colorectal surgeon advances a flexible endoscope through the colon to examine the bowel, commonly for evaluation of symptoms or an abnormal finding. The service can include specimen collection by brushing or washing, but it does not describe taking tissue for biopsy or treating a lesion. It is typically performed in an endoscopy unit or hospital outpatient department, with sedation commonly provided as part of the procedural setting.

Choose this code when the documented service is diagnostic inspection rather than a more specific colonoscopy procedure. The report should support the examination performed and whether a biopsy or treatment was done; when a more specific procedure is performed, report that service rather than separately reporting the diagnostic examination. CMS assigns a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures occur in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. Modifier 50 is inappropriate. Modifier 53 is separately priced. Medicare does not pay an assistant at surgery for this code, and co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 45378 pays more and less in Oregon

45378 office and facility rates by payment locality
Payment localityOfficeFacility
Portland$404.95$167.83
Rest Of Oregon$373.00$160.42

How the 45378 rate is calculated

Each of 45378’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 45378

RVUs × geographic indexes × conversion factor

Work3.18

3.18 RVUs× 1.000 GPCI

Practice expense7.73

7.73 RVUs× 1.000 GPCI

Malpractice0.41

0.41 RVUs× 1.000 GPCI

Adjusted RVUs

11.3200

Conversion factor

$33.4009

Medicare rate

$378.10

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 45378

The CMS indicators that decide how 45378 is paid alongside other services.

CMS payment indicators · 45378

Colonoscopy

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

45378 without 51 · national office

$378.10

Colonoscopy

45378-51 · Second procedure: 50%

$189.05

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

45378 compared with similar codes

Compare codes · National

5 codes, side by side

  • 45378

    Colonoscopy3.18 wRVU

    $378.10

  • 45380

    Colonoscopy with biopsy3.47 wRVU

    $479.97+$101.87

  • 45385

    Snare polypectomy4.46 wRVU

    $500.01+$121.91

  • 45330

    Flexible sigmoidoscopy0.82 wRVU

    $215.10−$163.00

  • 45379

    Colonoscopy4.17 wRVU

    $479.30+$101.20

How to choose

45380Colonoscopy with biopsy
Use 45380 when tissue is sampled for biopsy. Use 45378 when the exam is diagnostic and no tissue biopsy is performed.
45385Snare polypectomy
Use 45385 when a lesion is removed by snare. Diagnostic inspection alone is reported with 45378.
45330Flexible sigmoidoscopy
45330 describes diagnostic flexible sigmoidoscopy of a limited portion of the lower bowel; 45378 is for a colonoscopy.
45379Colonoscopy
45379 applies when a foreign body is removed during colonoscopy. Without that removal or another therapeutic procedure, the diagnostic service is 45378.

45378 billing questions

When should 45378 be chosen instead of 45380?

Use 45378 for diagnostic inspection without tissue biopsy. When tissue is sampled for histologic examination, report the biopsy service, 45380, instead.

Can 45378 be reported with a colonoscopy that removes a polyp?

The diagnostic inspection is part of the colonoscopy with polyp removal; report the code for the removal method rather than separately billing 45378 for the same examination.

Is modifier 50 appropriate for 45378?

No. CMS identifies bilateral adjustment as inappropriate for this code.

How should modifier 53 be handled?

CMS lists modifier 53 as separately priced for 45378. The record should support that the colonoscopy was discontinued; apply the modifier only when the circumstances meet its reporting requirements.

Does the 0-day global period include same-day care?

Yes. Same-day preoperative and postoperative care is included in the procedure's 0-day global period.

How many units are reported for the diagnostic examination?

Report one service for the colonoscopy, not a separate unit for each segment examined.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 45378PPRRVU2026_Oct_nonQPP.csv, line 5,513 (RVU26D)

Open CMS sourceHow we calculate rates

Did this answer your question about what 45378 pays in Oregon?

Tell us what you were actually trying to work out. We’ll answer you directly, or build the page that does.

Fee sheets

Put 45378 and the rest of your codes on one sheet

Build a fee sheet from your own code list at your locality, put your payer contracts beside Medicare, and see what changed each quarter.

Build my fee sheetOr price your code list free →