HCPCS Q4395: AcelagraftMedicare rate & RVUs in Oregon

Q4395 reports Acelagraft by square centimeter as a wound-care product used with a primary procedure that applies the material.

CMS RVU26DEffective Oct 1, 20262 payment localities

Medicare pays $126.75–$141.38 for Q4395 in the office in Oregon, from Rest Of Oregon to Portland. Which amount applies depends on the service address.

$126.75–$141.38Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4395 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Oregon
  2. What Q4395 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4395 covers

Q4395 identifies Acelagraft by square centimeter for wound-care use. It represents the product, not the clinical work of preparing the wound or applying the graft. Wound-care clinicians, surgeons, and other qualified practitioners may use the material while treating a wound in an office, wound clinic, or hospital setting. The product and quantity reported should match what was actually used; the code alone does not identify the wound type or treatment method.

Report Q4395 with the primary procedure that applies the product. CMS treats it as an add-on and pays it within that procedure’s global period, so it is not a stand-alone service. Document the product identity, wound site and dimensions, amount used, and related application procedure to support the reported units. CMS classifies Q4395 as technical-component-only; interpretation is represented by a separate code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4395 pays more and less in Oregon

Q4395 office and facility rates by payment locality
Payment localityOfficeFacility
Portland$141.38Unavailable
Rest Of Oregon$126.75Unavailable

How the Q4395 rate is calculated

Each of Q4395’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4395

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4395

The CMS indicators that decide how Q4395 is paid alongside other services.

CMS payment indicators · Q4395

Acelagraft

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4395 compared with similar codes

Compare codes · National

5 codes, side by side

  • Q4395

    Acelagraft0 wRVU

    $127.26

  • 15271

    Skin substitute graft1.46 wRVU

    $157.99+$30.73

  • 15273

    Skin substitute graft3.41 wRVU

    $321.98+$194.72

  • Q4394

    Wound graft0 wRVU

    $127.26+$0.00

  • Q4396

    Natalin graft0 wRVU

    $127.26+$0.00

How to choose

15271Skin substitute graft
Q4395 identifies the Acelagraft product; 15271 reports application for qualifying wounds on the trunk, arms, or legs. The codes represent different parts of the service.
15273Skin substitute graft
Q4395 identifies the product. Use 15273 for application to qualifying wounds on the face, scalp, neck, hands, feet, or genitalia.
Q4394Wound graft
Q4394 identifies Surgraft ACA, while Q4395 identifies Acelagraft. Select the product code that matches the material used.
Q4396Natalin graft
Q4396 identifies Natalin, not Acelagraft. The product documented as used determines which code applies.

Q4395 billing questions

Can Q4395 be reported by itself?

No. CMS identifies it as an add-on code, so report it with the primary procedure that applies the product.

How should the quantity be supported?

The descriptor is per square centimeter. Document the product used and the amount applied, along with the wound site and dimensions.

Does Q4395 include wound preparation or application?

No. Q4395 identifies the Acelagraft product; the primary procedure represents the application service.

Is interpretation included in Q4395?

No. CMS classifies Q4395 as technical-component-only and identifies interpretation as covered by a separate code.

When is Q4395 paid in relation to the primary procedure?

CMS places payment for Q4395 within the primary procedure’s global period. Report it with the related primary procedure rather than as a separate stand-alone service.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4395PPRRVU2026_Oct_nonQPP.csv, line 18,480 (RVU26D)

Open CMS sourceHow we calculate rates

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