Billing code 88120: Urine FISHMedicare rate & RVUs in Texas

Reports FISH analysis of a urinary tract specimen using three to five molecular probes, commonly to assess for urothelial carcinoma-associated chromosomal changes.

CMS RVU26DEffective Oct 1, 20268 payment localities55K Medicare services in 2024

Medicare pays $496.86–$571.06 for 88120 in the office in Texas, from Beaumont to Austin. Which amount applies depends on the service address.

$496.86–$571.06Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88120 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Texas
  2. What 88120 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 88120 covers

This service uses fluorescent in situ hybridization to assess cells in a urinary tract specimen for chromosomal changes associated with urothelial carcinoma. It is commonly used in the evaluation or surveillance of patients with a history of bladder cancer, including when urine testing is used to look for evidence of recurrent disease. Laboratory personnel prepare and process the specimen; a pathologist interprets the findings. The code represents analysis with three to five probes for each specimen, rather than conventional microscopic urine cytology.

Report one unit for each specimen analyzed under the three-to-five-probe method. Documentation should identify the specimen, the FISH analysis performed, the probes or probe set used, and the interpreted result. CMS recognizes professional and technical components: modifier 26 identifies the interpretation, and modifier TC identifies the equipment and staff work. Report without either modifier when billing the global service, which includes both components.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 88120 pays more and less in Texas

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

8 payment localities

$496.86 to $571.06

$496.86$533.96$571.06
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

8 of 8 payment localities

88120 office and facility rates by payment locality
Payment localityOfficeFacility
Austin$571.06Unavailable
Beaumont$496.86Unavailable
Brazoria$537.53Unavailable
Dallas$540.21Unavailable
Fort Worth$535.21Unavailable
Galveston$538.61Unavailable
Houston$539.53Unavailable
Rest Of Texas$516.37Unavailable

How the 88120 rate is calculated

Each of 88120’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88120

RVUs × geographic indexes × conversion factor

Work1.17

1.17 RVUs× 1.000 GPCI

Practice expense15.01

15.01 RVUs× 1.000 GPCI

Malpractice0.05

0.05 RVUs× 1.000 GPCI

Adjusted RVUs

16.2300

Conversion factor

$33.4009

Medicare rate

$542.10

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 88120

The CMS indicators that decide how 88120 is paid alongside other services.

CMS payment indicators · 88120

Urine FISH

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88120 without 26 · national office

$542.10

Urine FISH

88120-26 · Professional component

$54.44

Pays only the interpretation and report.

When to use modifier 26

88120 compared with similar codes

Compare codes · National

4 codes, side by side

  • 88120

    Urine FISH1.17 wRVU

    $542.10

  • 88121

    Urine FISH0.98 wRVU

    $393.80−$148.30

  • 88112

    Selective-enhancement cytology0.55 wRVU

    $65.47−$476.63

  • 88108

    Concentrated cytology0.43 wRVU

    $68.81−$473.29

How to choose

88121Urine FISH
Both apply to urinary tract specimen FISH with three to five probes. The distinction is computer-assisted analysis under 88121 versus the method represented by 88120.
88112Selective-enhancement cytology
88112 reports cell-enhanced cytopathology preparation and examination. 88120 reports FISH probe analysis for chromosomal changes, not cell morphology alone.
88108Concentrated cytology
88108 is for cytopathology of a concentrated fluid specimen. 88120 is selected for urinary tract specimen FISH using three to five molecular probes.

88120 billing questions

How does 88120 differ from 88121?

Both describe urinary tract specimen FISH using three to five probes. 88121 is the related code for analysis using computer-assisted technology; select the code that matches the method documented.

Is this conventional urine cytology?

No. This code is for fluorescent in situ hybridization to detect chromosomal changes. Conventional cytology evaluates cell appearance and is reported with a different cytopathology code.

How many units are reported?

Report per specimen analyzed with the three-to-five-probe method. The probe count does not create a separate unit for each probe.

When should modifier 26 or TC be used?

Use modifier 26 for the professional interpretation alone and modifier TC for the technical work alone. An unmodified claim represents the global service, including both components.

What documentation supports the service?

Record the urinary tract specimen, the FISH method and probe set, the analysis performed, and the interpreted findings. The documentation should support that three to five probes were used for each specimen.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88120PPRRVU2026_Oct_nonQPP.csv, line 11,115 (RVU26D)

Open CMS sourceHow we calculate rates

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