Billing code 88380: Tissue microdissectionMedicare rate & RVUs in Utah

Reports laser capture microdissection of a tissue section to isolate selected cells, typically preparing a specimen for downstream molecular analysis.

CMS RVU26DEffective Oct 1, 20261 payment locality334 Medicare services in 2024

Medicare pays $112.69 for 88380 in the office in Utah (Utah). Which amount applies depends on the service address.

$112.69Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88380 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Utah
  2. What 88380 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 88380 covers

A laboratory uses a laser under microscopic visualization to separate selected cells or tissue from a section, such as a tumor focus mixed with surrounding benign tissue. The enriched material can then be used for molecular testing. This service is typically performed by pathology laboratory personnel as part of a surgical pathology or molecular diagnostic workflow; the interpreting pathologist may provide the professional component.

Report the service for each tissue section subjected to laser capture microdissection. Documentation should identify the specimen and section, the tissue or cell population selected, and the laser-capture work performed. This code represents specimen preparation, not the downstream molecular assay or its interpretation. CMS recognizes professional and technical components: modifier 26 identifies the professional interpretation, modifier TC identifies the technical service, and an unmodified claim represents the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

88380 in Utah

88380 office and facility rates by payment locality
Payment localityOfficeFacility
Utah$112.69Unavailable

How the 88380 rate is calculated

Each of 88380’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88380

RVUs × geographic indexes × conversion factor

Work1.11

1.11 RVUs× 1.000 GPCI

Practice expense2.37

2.37 RVUs× 1.000 GPCI

Malpractice0.04

0.04 RVUs× 1.000 GPCI

Adjusted RVUs

3.5200

Conversion factor

$33.4009

Medicare rate

$117.57

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 88380

The CMS indicators that decide how 88380 is paid alongside other services.

CMS payment indicators · 88380

Tissue microdissection

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88380 without 26 · national office

$117.57

Tissue microdissection

88380-26 · Professional component

$48.43

Pays only the interpretation and report.

When to use modifier 26

88380 compared with similar codes

Compare codes · National

4 codes, side by side

  • 88380

    Tissue microdissection1.11 wRVU

    $117.57

  • 88381

    Microdissection0.52 wRVU

    $187.71+$70.14

  • 88387

    Tissue preparation0.6 wRVU

    $32.73−$84.84

  • 88363

    Tissue preparation0.36 wRVU

    $22.71−$94.86

How to choose

88381Microdissection
Choose 88380 when a laser captures selected tissue from a section; 88381 describes manual microdissection.
88387Tissue preparation
88387 covers macroscopic examination, dissection, and preparation of tissue for molecular studies. 88380 is the laser-based isolation of selected cells or tissue.
88363Tissue preparation
88363 concerns retrieval of archived tissue for molecular analysis; 88380 reports laser capture microdissection of tissue from a section.

88380 billing questions

How is 88380 different from manual microdissection?

88380 is for laser capture of selected tissue from a section. Use 88381 when the microdissection is performed manually.

Does 88380 include the molecular test?

No. It represents laser-based isolation of tissue for analysis, not the downstream molecular assay or its result.

Which modifiers identify the components?

Modifier 26 reports the professional component, modifier TC reports the technical component, and no modifier represents the global service.

What supports reporting the service?

Record the specimen and tissue section, the selected cell population or target tissue, and that laser capture microdissection was performed.

How many units are reported?

The code is reported per tissue section subjected to laser capture microdissection. The documentation should support the number of sections processed.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88380PPRRVU2026_Oct_nonQPP.csv, line 11,317 (RVU26D)
Geographic factors for UtahGPCI2026.csv, line 104 (RVU26D)

Open CMS sourceHow we calculate rates

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