HCPCS Q4166: Wound matrixMedicare rate & RVUs in Utah

Reports Cytal extracellular matrix material used on a wound bed, measured by area and billed with the related wound application procedure.

CMS RVU26DEffective Oct 1, 20261 payment locality

Medicare pays $119.62 for Q4166 in the office in Utah (Utah). Which amount applies depends on the service address.

$119.62Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4166 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Utah
  2. What Q4166 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4166 covers

Cytal is an extracellular matrix wound product derived from porcine urinary bladder tissue. A wound-care clinician may apply it to a prepared wound bed, including in the treatment of chronic wounds such as diabetic foot or venous leg ulcers. The product amount is reported by the square centimeter, rather than by the number of wounds or a time increment.

Report Q4166 with the primary wound application procedure for the same treatment, using documentation that identifies Cytal, the treated wound site, and the quantity applied in square centimeters. CMS classifies this as an add-on code: it must be billed with a primary procedure and is paid within that procedure's global period. CMS also identifies it as technical-component-only, with interpretation covered by a separate code rather than this line. The application service and the Cytal material are distinct reported items.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Q4166 in Utah

Q4166 office and facility rates by payment locality
Payment localityOfficeFacility
Utah$119.62Unavailable

How the Q4166 rate is calculated

Each of Q4166’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4166

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4166

The CMS indicators that decide how Q4166 is paid alongside other services.

CMS payment indicators · Q4166

Wound matrix

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4166 compared with similar codes

Compare codes

Q4166 vs Q4165 vs Q4167 vs 15271: national Medicare rates

Swap in your local Medicare rate.

  • Q4166
    Wound matrix · 0 wRVU
    $127.26
  • Q4165
    Wound matrix · 0 wRVU
    $127.26+$0.00
  • Q4167
    Wound product · 0 wRVU
    $127.26+$0.00
  • 15271
    Skin substitute graft · 1.46 wRVU
    $157.99+$30.73

How to choose

Q4165Wound matrix
Q4165 identifies Keramatrix or Kerasorb. Q4166 is specific to Cytal; select according to the product actually furnished.
Q4167Wound product
Q4167 identifies TruSkin, not Cytal. Both are area-based wound product codes, but the product determines which code applies.
15271Skin substitute graft
15271 reports the wound application service for qualifying trunk or extremity sites. Q4166 reports the Cytal material and must accompany a primary procedure.

Q4166 billing questions

When is Q4166 reported instead of another wound product code?

Use Q4166 when the material furnished is Cytal. Other wound matrices have their own HCPCS codes, even when they are applied to a similar wound.

Can Q4166 be billed by itself?

No. CMS identifies it as an add-on code that must be billed with a primary procedure; it is paid within that procedure's global period.

Is the wound application included in Q4166?

Q4166 reports the Cytal material by area, while the primary wound application procedure reports the clinician's application service. Document both the product amount and the application performed.

What supports the number of units?

Document the Cytal quantity used in square centimeters, along with the wound site and product identity. The code is measured by area, not by wound count or time.

Does Q4166 include a professional interpretation?

CMS classifies Q4166 as technical-component-only and assigns interpretation to a separate code. Q4166 itself reports the Cytal material.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4166PPRRVU2026_Oct_nonQPP.csv, line 18,259 (RVU26D)
Geographic factors for UtahGPCI2026.csv, line 104 (RVU26D)

Open CMS sourceHow we calculate rates

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