Billing code 78451: Cardiac SPECTMedicare rate & RVUs in Virginia

Reports one SPECT myocardial perfusion study at rest or stress to assess blood flow to the heart muscle in suspected or known coronary disease.

CMS RVU26DEffective Oct 1, 20262 payment localities20.3K Medicare services in 2024

Medicare pays $305.85–$360.90 for 78451 in the office in Virginia, from Virginia to Dc + Md/Va Suburbs. Which amount applies depends on the service address.

$305.85–$360.90Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 78451 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Virginia
  2. What 78451 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 78451 covers

This service uses a radiopharmaceutical and a gamma camera to create tomographic images of myocardial perfusion for one study, performed at rest or under exercise or pharmacologic stress. Cardiologists, nuclear medicine physicians, and radiologists may interpret the images in hospital or outpatient imaging settings. Clinicians commonly use the study to evaluate suspected or established coronary artery disease and possible ischemia or prior myocardial injury.

Report 78451 for a single rest or stress study; when both rest and stress studies are performed, 78452 is the related SPECT code. Documentation should identify the study condition and support the imaging and interpretation performed. The code has professional and technical components: modifier 26 identifies the interpretation, modifier TC identifies equipment and staff, and no component modifier represents the global service. The cardiovascular diagnostic multiple procedure reduction applies to the technical component.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 78451 pays more and less in Virginia

78451 office and facility rates by payment locality
Payment localityOfficeFacility
Dc + Md/Va Suburbs$360.90Unavailable
Virginia$305.85Unavailable

How the 78451 rate is calculated

Each of 78451’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 78451

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.35Practice expense 7.87Malpractice 0.10

9.3200 adjusted RVUs×$33.4009 conversion factor=$311.30

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 78451

The CMS indicators that decide how 78451 is paid alongside other services.

CMS payment indicators · 78451

Cardiac SPECT

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures6Diagnostic cardiovascular reduction applies to the technical component.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

78451 without 26 · national office

$311.30

Cardiac SPECT

78451-26 · Professional component

$63.13

Pays only the interpretation and report.

When to use modifier 26

78451 compared with similar codes

Compare codes

78451 vs 78452 vs 78453 vs 78454 vs 78491: national Medicare rates

Swap in your local Medicare rate.

  • 78451
    Cardiac SPECT · 1.35 wRVU
    $311.30
  • 78452
    Nuclear stress test · 1.58 wRVU
    $427.87+$116.57
  • 78453
    Heart perfusion imaging · 0.98 wRVU
    $262.87−$48.43
  • 78454
    Heart imaging · 1.31 wRVU
    $382.11+$70.81
  • 78491
    · 0 wRVU
    —

How to choose

78452Nuclear stress test
Both describe myocardial perfusion SPECT. Choose 78451 for one rest or stress study; 78452 represents multiple studies, commonly rest and stress.
78453Heart perfusion imaging
78453 describes a single myocardial perfusion study using planar imaging. 78451 is for tomographic SPECT imaging.
78454Heart imaging
78454 is the multiple-study planar myocardial perfusion code. 78451 is tomographic SPECT for a single study.
78491Myocrd img pet 1std rst/strs
78491 is myocardial perfusion imaging with PET. Use 78451 when the modality performed is SPECT.

78451 billing questions

When is 78451 reported instead of 78452?

Use 78451 for one SPECT myocardial perfusion study at rest or stress. When the service includes both rest and stress studies, compare the documentation with 78452.

Does one study mean one image or one view?

No. The distinction is the number of myocardial perfusion studies, not the number of image slices or views. Document whether the single study was performed at rest or stress.

How should the professional and technical work be billed?

Use modifier 26 for the physician's interpretation and modifier TC for the equipment and staff. Report the global service without either component modifier when one claim includes both portions.

Can the technical component be reduced when other tests are performed?

The cardiovascular diagnostic multiple procedure reduction applies to the technical component of 78451. It does not change the professional component under the CMS rule provided.

What documentation supports 78451?

Document that myocardial perfusion SPECT was performed, whether the single study was at rest or stress, and the physician's interpretation. For stress imaging, identify the stress method used.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 78451PPRRVU2026_Oct_nonQPP.csv, line 9,365 (RVU26D)

Open CMS sourceHow we calculate rates

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