CPT code 0662U: Transplant assay, urine mRNA, 12 genes2026 Medicare lab fee · Clinical Laboratory Fee Schedule
A urine mRNA profile of 12 genes uses real-time PCR to produce a rejection-risk score during evaluation of kidney allograft rejection.
Medicare has no national amount for 0662U: it’s on the 2026 Clinical Laboratory Fee Schedule as contractor-priced, so each Medicare Administrative Contractor sets the payment.
Medicare lab fee · CLFS 2026 Q4
Contractor-priced (CLFS indicator L)
Set by your MAC
CMS lists 0662U on the Clinical Laboratory Fee Schedule without a national amount: each Medicare Administrative Contractor prices it for its jurisdiction.
- National amount
- None
- Priced by
- Each MAC
- Fee schedule
- Clinical lab
- CMS updates
- Quarterly
The contractor that processes the claim sets the amount for its jurisdiction. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 7 sections
What 0662U covers
0662U identifies a urine-based gene-expression assay used in evaluating kidney allograft rejection. The laboratory measures mRNA from 12 genes by real-time quantitative PCR: 11 content genes and one housekeeping gene. An algorithm converts the profile into a rejection-risk score. The result provides a molecular assessment rather than tissue findings from a kidney biopsy. Transplant clinicians may use the result when evaluating a kidney transplant recipient for possible rejection.
Report the assay under 0662U as a proprietary laboratory analysis. Medicare pays 0662U through the CLFS with local pricing set by each Medicare Administrative Contractor. The code entered the CLFS effective October 1, 2026. No physician fee schedule payment row is assigned to this code.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 0662U
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
Priced by each contractor
0662U carries CLFS indicator L: CMS publishes no national amount, and each Medicare Administrative Contractor sets the payment for its jurisdiction. Ask your MAC for its current amount.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Not on the physician fee schedule
The physician fee schedule doesn’t list 0662U: Medicare pays the test only from the CLFS.
0662U compared with similar tests
- 0664UKidney transplant profile13-gene NGS risk scoreNo national amount
- 0662U profiles urine mRNA by real-time PCR and reports a rejection-risk score. 0664U is identified as a 13-gene transplant-medicine NGS assay.
- 50200Renal biopsyPercutaneous$430.79–$676.47
- 50200 represents a percutaneous renal biopsy that obtains tissue. 0662U describes a urine-based molecular profile, not a biopsy.
0662U billing questions
What specimen and method does 0662U describe?
It profiles mRNA from a urine specimen using real-time quantitative PCR across 12 genes.
What does the test report?
An algorithm reports a rejection-risk score for assessment of kidney allograft rejection.
How does 0662U differ from 0664U?
0662U describes a 12-gene urine mRNA profile by real-time PCR. 0664U is identified as a 13-gene transplant-medicine NGS assay; report the code for the test performed.
How does Medicare pay for 0662U?
Medicare pays it through the CLFS using local pricing set by each Medicare Administrative Contractor.
Does 0662U represent a kidney biopsy?
No. It describes a urine-based molecular profile; 50200 represents a percutaneous renal biopsy that obtains tissue.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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