CPT code 0663U: Fetal platelet test, selected HPA antigens2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Cell-free DNA testing detects selected fetal platelet antigens and reports maternal-fetal incompatibility status for prenatal evaluation.
Medicare has no national amount for 0663U: it’s on the 2026 Clinical Laboratory Fee Schedule as contractor-priced, so each Medicare Administrative Contractor sets the payment.
Medicare lab fee · CLFS 2026 Q4
Contractor-priced (CLFS indicator L)
Set by your MAC
CMS lists 0663U on the Clinical Laboratory Fee Schedule without a national amount: each Medicare Administrative Contractor prices it for its jurisdiction.
- National amount
- None
- Priced by
- Each MAC
- Fee schedule
- Clinical lab
- CMS updates
- Quarterly
The contractor that processes the claim sets the amount for its jurisdiction. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 6 sections
What 0663U covers
0663U is a cell-free DNA prenatal laboratory analysis that detects whether the fetus has selected human platelet antigens, including HPA-1a, HPA-1b, HPA-3a, HPA-5b, and other antigens. The laboratory reports maternal-fetal incompatibility as detected or not detected for each selected antigen. This test evaluates fetal platelet antigen status rather than fetal chromosome conditions or maternal platelet antibodies.
Report 0663U for the cell-free DNA antigen analysis, with the result stated per selected antigen. Medicare pays the code through the Clinical Laboratory Fee Schedule (CLFS); each Medicare Administrative Contractor sets the locally priced payment. The CLFS payment has no geographic adjustment or office/facility difference. The code was added to the CLFS effective October 1, 2026. Medicare payment for this code is through the CLFS only.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 0663U
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
Priced by each contractor
0663U carries CLFS indicator L: CMS publishes no national amount, and each Medicare Administrative Contractor sets the payment for its jurisdiction. Ask your MAC for its current amount.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Not on the physician fee schedule
The physician fee schedule doesn’t list 0663U: Medicare pays the test only from the CLFS.
0663U compared with similar tests
- 81420Fetal aneuploidyMaternal blood, genomic panel$759.05
- 81420 is prenatal cell-free DNA testing for fetal chromosomal aneuploidy. Use 0663U when the analysis detects selected fetal platelet antigens.
- 86022Platelet antibodiesAntibody identification$18.37
- 86022 detects platelet antibodies. It evaluates antibody status rather than selected fetal platelet antigens measured by 0663U.
- 86023Platelet Ig assayPlatelet-associated immunoglobulin$12.46
- 86023 identifies platelet antibodies; 0663U analyzes cell-free DNA to detect selected fetal platelet antigens.
0663U billing questions
How is 0663U different from prenatal aneuploidy testing?
0663U detects selected fetal platelet antigens and reports maternal-fetal incompatibility. Prenatal aneuploidy testing evaluates fetal chromosomal conditions.
What result does this test report?
The laboratory reports whether maternal-fetal incompatibility was detected or not detected for each selected antigen.
Does Medicare pay separately for a physician interpretation?
Medicare pays 0663U through the CLFS only.
How is Medicare payment set for 0663U?
The code is locally priced under the CLFS, and each Medicare Administrative Contractor sets the payment.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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