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CPT code 20205: Muscle biopsy, open deep-muscle approach2026 Medicare rate & RVUs in South Carolina

Reports open sampling of deep muscle tissue for diagnostic evaluation when a superficial sample or percutaneous needle approach is not the method performed.

CMS RVU26DEffective Oct 1, 2026One payment locality2K Medicare services in 2024

In South Carolina, Medicare pays $317.15 for 20205 in the office and $140.00 when it’s performed in a hospital or facility.

$317.15Office (non-facility)
$140.00Hospital or facility
−6.4%vs the national office rate ($338.69)

Check a contract rate as a % of Medicare · 20205 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 20205 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Carolina
  2. What 20205 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 20205 covers

The clinician obtains a muscle specimen through an incision that reaches deep muscle tissue. This approach may be selected when evaluation of suspected neuromuscular disease requires tissue for laboratory examination and a needle sample is not performed. A surgeon commonly performs the procedure in a hospital or ambulatory surgery setting; the specimen is sent for pathologic evaluation.

Select this code for an open biopsy of deep muscle, not a superficial muscle sample or percutaneous needle biopsy. The operative note should identify the muscle sampled and document the open approach and depth. Same-day preoperative and postoperative care is included in the 0-day global period. When other procedures occur in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard multiple-procedure reduction. Modifier 50 is inappropriate for this descriptor and anatomy. Medicare does not pay an assistant at surgery for this code; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Carolina compares for 20205

Across 109 of 109 payment localities, the office rate for 20205 runs from $294.25 in Arkansas to $443.32 in San Benito County, CA. South Carolina pays $317.15. The RVUs are the same everywhere; the geographic indexes change the dollars.

20205 in South Carolina vs other payment areas
  1. South Carolina · this page$317.15
  2. Los Angeles, CA · California$378.54+$61.39
  3. Washington, DC area · District of Columbia$388.08+$70.93
  4. Miami, FL · Florida$381.74+$64.59
  5. Chicago, IL · Illinois$368.54+$51.39
  6. Manhattan, NY · New York$395.26+$78.11
  7. Alaska · Alaska$382.81+$65.66

Other areas in South Carolina first, then benchmark localities. Bars start at $0.

Every other payment area

20205 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$299.20$131.45
ArkansasArkansas$294.25$129.56
ArizonaArizona$328.10$142.33
Bakersfield, CACalifornia$354.74$144.61
Chico, CACalifornia$353.00$142.87
El Centro, CACalifornia$353.11$142.98
Fresno, CACalifornia$353.00$142.87
Hanford, CACalifornia$353.00$142.87

20205 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$294.25

$398.16

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
20205 office rate range by state
State / territoryOffice rate rangeLocalities
AK$382.811
AL$299.201
AR$294.251
AZ$328.101
CA$353.00–$443.3229
CO$350.241
CT$363.291
DC$388.081
DE$333.991
FL$339.02–$381.743
GA$316.88–$347.132
GU$362.491
HI$362.491
IA$305.151
ID$308.001
IL$329.99–$368.544
IN$309.971
KS$304.831
KY$310.151
LA$310.12–$327.452
MA$348.25–$386.092
MD$340.56–$388.083
ME$311.24–$328.512
MI$320.56–$345.162
MN$330.371
MO$304.93–$327.193
MS$299.591
MT$338.641
NC$314.741
ND$325.791
NE$306.661
NH$345.831
NJ$365.98–$383.462
NM$323.091
NV$335.301
NY$320.21–$407.645
OH$317.941
OK$308.111
OR$331.28–$361.052
PA$317.77–$354.112
PR$341.001
RI$345.731
SC$317.151
SD$324.271
TN$306.751
TX$315.50–$350.318
UT$322.041
VA$328.21–$388.082
VI$341.001
VT$325.561
WA$347.24–$393.132
WI$313.561
WV$316.541
WY$333.041

See 20205 in every payment locality

How the 20205 rate is calculated

Each of 20205’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 20205

RVUs × geographic indexes × conversion factor

Office or facility?

Work2.29

2.29 RVUs× 1.000 GPCI

Practice expense7.20

7.20 RVUs× 1.000 GPCI

Malpractice0.65

0.65 RVUs× 1.000 GPCI

Adjusted RVUs

10.1400

Conversion factor

$33.4009

Medicare rate

$338.69

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Carolina inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

1,728

Code
20205
Physician work
2.29
Practice expense
7.20
Malpractice
0.65

GPCI2026.csv

93

Locality
South Carolina
Physician work
1.000
Practice expense
0.924
Malpractice
0.850
Office calculation for 20205 in South Carolina
ComponentRVULocality factorAdjusted
Physician work2.29× 1.0002.2900
Practice expense7.20× 0.9246.6528
Malpractice0.65× 0.8500.5525
Total RVUs9.4953
Conversion factor× 33.4009

Office rate, South Carolina$317.15

Office: (2.29 × 1 + 7.2 × 0.924 + 0.65 × 0.85) × $33.4009 = $317.15

Facility: (2.29 × 1 + 1.46 × 0.924 + 0.65 × 0.85) × $33.4009 = $140.00

Open 20205 in the RVU calculator

Payment rules and modifiers for 20205

The CMS indicators that decide how 20205 is paid alongside other services.

CMS payment indicators · 20205

Muscle biopsy, open deep-muscle approach

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

20205 without 51 · national office

$338.69

Muscle biopsy, open deep-muscle approach

20205-51 · Second procedure: 50%

$169.35

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

Codes related to 20205

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 20205
CodeHow it relatesOffice range, South Carolina
Same family
20200Muscle biopsy, superficial, open approachOpen muscle biopsy at a superficial rather than deep level.$226.13
Used instead
20206Muscle biopsy, percutaneous needle approachPercutaneous needle approach for sampling muscle rather than an open approach.$196.01
Often billed with
88305Tissue pathology exam, level IV specimenMay report the separate pathologic examination of the muscle specimen.$66.61

How 20205 has changed in South Carolina

20205 · Office / nonfacility

$317.15

Effective 2026-10-01

The base rate is $45.55 higher than on 2025-10-01, moving from $271.60 to $317.15 (16.8%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $271.60changed to$317.15

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 2.35 changed to 2.29
    • Practice expense RVU 6.05 changed to 7.20
    • Malpractice RVU 0.64 changed to 0.65
    • Practice expense GPCI 0.913 changed to 0.924
    • Malpractice GPCI 0.817 changed to 0.850

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $282.78changed to$271.60

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 6.14 changed to 6.05
    • Malpractice RVU 0.66 changed to 0.64

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $278.16changed to$282.78

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $285.83changed to$278.16

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 6.16 changed to 6.14
    • Malpractice RVU 0.65 changed to 0.66
    • Practice expense GPCI 0.908 changed to 0.913
    • Malpractice GPCI 0.756 changed to 0.817

  5. January 1, 2023

    RVU23A

    $290.92changed to$285.83

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 6.23 changed to 6.16
    • Malpractice RVU 0.62 changed to 0.65
    • Practice expense GPCI 0.903 changed to 0.908
    • Malpractice GPCI 0.695 changed to 0.756

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $294.59changed to$290.92

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 6.27 changed to 6.23

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $279.01changed to$294.59

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 5.52 changed to 6.27
    • Malpractice RVU 0.60 changed to 0.62
    • Practice expense GPCI 0.907 changed to 0.903
    • Malpractice GPCI 0.624 changed to 0.695

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $273.75changed to$279.01

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 5.37 changed to 5.52
    • Malpractice RVU 0.63 changed to 0.60
    • Practice expense GPCI 0.912 changed to 0.907
    • Malpractice GPCI 0.553 changed to 0.624

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $270.69changed to$273.75

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 5.28 changed to 5.37
    • Malpractice RVU 0.64 changed to 0.63

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $270.74changed to$270.69

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 5.25 changed to 5.28
    • Malpractice GPCI 0.634 changed to 0.553

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $272.28changed to$270.74

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 5.26 changed to 5.25
    • Malpractice GPCI 0.715 changed to 0.634

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $272.94changed to$272.28

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 5.25 changed to 5.26

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $271.58changed to$272.94

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $266.16changed to$271.58

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 5.21 changed to 5.25
    • Malpractice RVU 0.54 changed to 0.64
    • Practice expense GPCI 0.911 changed to 0.912
    • Malpractice GPCI 0.618 changed to 0.715

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $271.40changed to$266.16

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 5.87 changed to 5.21
    • Malpractice RVU 0.56 changed to 0.54
    • Practice expense GPCI 0.909 changed to 0.911
    • Malpractice GPCI 0.520 changed to 0.618

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $271.40

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$317.15$140.00RVU26D
2026-07-01$317.15$140.00RVU26C
2026-04-01$317.15$140.00RVU26B
2026-01-01$317.15$140.00RVU26A
2025-10-01$271.60$142.84RVU25D
2025-07-01$271.60$142.84RVU25C
2025-04-01$271.60$142.84RVU25B
2025-01-01$271.60$142.84RVU25A
2024-10-01$282.78$146.32RVU24D
2024-07-01$282.78$146.32RVU24C
2024-04-01$282.78$146.32RVU24B
2024-03-09$282.78$146.32RVU24AR
2024-01-01$278.16$143.93RVU24A
2023-10-01$285.83$145.83RVU23D
2023-07-01$285.83$145.83RVU23C
2023-04-01$285.83$145.83RVU23B
2023-01-01$285.83$145.83RVU23A
2022-10-01$290.92$145.61RVU22D
2022-07-01$290.92$145.61RVU22C
2022-04-01$290.92$145.61RVU22B
2022-01-01$290.92$145.61RVU22A
2021-10-01$294.59$146.50RVU21D
2021-07-01$294.59$146.50RVU21C
2021-04-01$294.59$146.50RVU21B
2021-01-01$294.59$146.50RVU21A
2020-10-01$279.01$147.10RVU20D
2020-07-01$279.01$147.10RVU20C
2020-04-01$279.01$147.10RVU20B
2020-01-01$279.01$147.10RVU20A
2019-10-01$273.75$146.55RVU19D
2019-07-01$273.75$146.55RVU19C
2019-04-01$273.75$146.55RVU19B
2019-01-01$273.75$146.55RVU19A
2018-10-01$270.69$147.24RVU18D
2018-07-01$270.69$147.24RVU18C
2018-04-01$270.69$147.24RVU18B
2018-01-01$270.69$147.24RVU18AR1
2017-10-01$270.74$148.65RVU17D
2017-07-01$270.74$148.65RVU17C
2017-04-01$270.74$148.65RVU17B
2017-01-01$270.74$148.65RVU17A
2016-10-01$272.28$150.16RVU16D
2016-07-01$272.28$150.16RVU16C
2016-04-01$272.28$150.16RVU16B
2016-01-01$272.28$150.16RVU16A
2015-10-01$272.94$150.70RVU15D
2015-07-01$272.94$150.70RVU15C
2015-04-01$271.58$149.95RVU15B
2015-01-01$271.58$149.95RVU15A
2014-10-01$266.16$146.07RVU14D
2014-07-01$266.16$146.07RVU14C
2014-04-01$266.16$146.07RVU14B
2014-01-01$266.16$146.07RVU14A
2013-10-01$271.40$141.51RVU13D
2013-07-01$271.40$141.51RVU13C
2013-04-01$271.40$141.51RVU13B
2013-01-01$271.40$141.51RVU13AR

Price 20205 for an earlier date of service

Where the South Carolina rate applies

South Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 475 cities and communities in South Carolina. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Abney Crossroads
  • Adams Run
  • Aiken
  • Alcolu
  • Allendale
  • Anderson
  • Andrews

Browse all communities in South Carolina

20205 billing questions

How is this distinguished from a superficial muscle biopsy?

Use 20205 when the open approach reaches deep muscle tissue. A superficial muscle sample is reported with 20200.

How does this differ from a percutaneous muscle biopsy?

This code describes an open approach to deep muscle. Use 20206 when the muscle is sampled percutaneously with a needle.

Is the pathology examination included?

The code reports obtaining the muscle specimen. A pathologist may separately report the tissue examination, such as 88305, when that service is performed and documented.

Can modifier 50 be used for biopsies on both sides?

Modifier 50 is inappropriate for this descriptor and anatomy, so do not report a bilateral adjustment.

Can an assistant surgeon or co-surgeon be reported?

Medicare does not pay an assistant at surgery for 20205. Co-surgeon and team-surgery reporting are not permitted.

What same-session payment reduction should the billing team expect?

When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and the others are subject to the standard 50% multiple-procedure payment.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 20205PPRRVU2026_Oct_nonQPP.csv, line 1,728 (RVU26D)
Geographic factors for South CarolinaGPCI2026.csv, line 93 (RVU26D)

Open CMS sourceHow we calculate rates

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