CPT code 20251: Vertebral biopsy, open, cervical or lumbar2026 Medicare rate & RVUs in Puerto Rico

Reports open tissue sampling from a cervical or lumbar vertebral body, commonly to investigate a suspected bone lesion or vertebral infection.

CMS RVU26DEffective Oct 1, 2026One payment locality270 Medicare services in 2024

In Puerto Rico, Medicare pays $422.33 for 20251 in a facility. There’s no office rate.

Not available in this settingOffice (non-facility)
$422.33Hospital or facility

Check a contract rate as a % of Medicare · 20251 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 20251 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Puerto Rico
  2. What 20251 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 20251 covers

This service involves surgically exposing a cervical or lumbar vertebral body and obtaining tissue for diagnostic evaluation, such as when imaging raises concern for a tumor or infection. A neurosurgeon or orthopedic spine surgeon typically performs it in an operating room. The code is specific to the vertebral body and an open approach; a needle or trocar sample through the skin is a different service.

Select the code when the operative report supports open sampling of a cervical or lumbar vertebral body. Document the spinal region and level, the open approach, and the tissue obtained. Related postoperative visits during the 10-day global period are included. When other procedures are performed in the same session, Medicare pays the highest-valued procedure in full and reduces the others to 50%. Modifier 50 is inappropriate. Medicare may pay for an assistant at surgery, but co-surgeon and team-surgery billing are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Puerto Rico compares for 20251

Across 109 of 109 payment localities, the facility rate for 20251 runs from $369.00 in Arkansas to $514.53 in NYC suburbs and Long Island, NY. Puerto Rico pays $422.33. The RVUs are the same everywhere; the geographic indexes change the dollars.

20251 in Puerto Rico vs other payment areas
  1. Puerto Rico · this page$422.33
  2. Los Angeles, CA · California$443.02+$20.69
  3. Washington, DC area · District of Columbia$469.44+$47.11
  4. Miami, FL · Florida$513.32+$90.99
  5. Chicago, IL · Illinois$495.19+$72.86
  6. Manhattan, NY · New York$494.66+$72.33
  7. Alaska · Alaska$501.14+$78.81

Other areas in Puerto Rico first, then benchmark localities. Bars start at $0.

Every other payment area

20251 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama—$374.70
ArkansasArkansas—$369.00
ArizonaArizona—$407.64
Bakersfield, CACalifornia—$420.27
Chico, CACalifornia—$415.85
El Centro, CACalifornia—$416.12
Fresno, CACalifornia—$415.85
Hanford, CACalifornia—$415.85

20251 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
20251 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

See 20251 in every payment locality

How the 20251 rate is calculated

Each of 20251’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 20251

RVUs × geographic indexes × conversion factor

Office or facility?

Work5.58

5.58 RVUs× 1.000 GPCI

Practice expense5.37

5.37 RVUs× 1.000 GPCI

Malpractice1.66

1.66 RVUs× 1.000 GPCI

Adjusted RVUs

12.6100

Conversion factor

$33.4009

Medicare rate

$421.19

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Puerto Rico inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

1,740

Code
20251
Physician work
5.58
Practice expense
5.37
Malpractice
1.66

GPCI2026.csv

91

Locality
Puerto Rico
Physician work
1.000
Practice expense
1.011
Malpractice
0.985
Facility calculation for 20251 in Puerto Rico
ComponentRVULocality factorAdjusted
Physician work5.58× 1.0005.5800
Practice expense5.37× 1.0115.4291
Malpractice1.66× 0.9851.6351
Total RVUs12.6442
Conversion factor× 33.4009

Facility rate, Puerto Rico$422.33

Facility: (5.58 × 1 + 5.37 × 1.011 + 1.66 × 0.985) × $33.4009 = $422.33

Open 20251 in the RVU calculator

Payment rules and modifiers for 20251

20251 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 20251

Vertebral biopsy, open, cervical or lumbar

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)2Paid.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 20251

Vertebral biopsy, open, cervical or lumbar

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

20251 without 51 · national facility

$421.19

Vertebral biopsy, open, cervical or lumbar

20251-51 · Second procedure: 50%

$210.60

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

How 20251 has changed in Puerto Rico

20251 · Office / nonfacility

Rate unavailable

Effective 2026-10-01

A rate is unavailable in one of these releases, so a change cannot be calculated.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01Not available in this setting$422.33RVU26D
2026-07-01Not available in this setting$422.33RVU26C
2026-04-01Not available in this setting$422.33RVU26B
2026-01-01Not available in this setting$422.33RVU26A
2025-10-01Not available in this setting$425.36RVU25D
2025-07-01Not available in this setting$425.36RVU25C
2025-04-01Not available in this setting$425.36RVU25B
2025-01-01Not available in this setting$425.36RVU25A
2024-10-01Not available in this setting$421.77RVU24D
2024-07-01Not available in this setting$421.77RVU24C
2024-04-01Not available in this setting$421.77RVU24B
2024-03-09Not available in this setting$421.77RVU24AR
2024-01-01Not available in this setting$414.89RVU24A
2023-10-01Not available in this setting$429.63RVU23D
2023-07-01Not available in this setting$429.01RVU23C
2023-04-01Not available in this setting$429.01RVU23B
2023-01-01Not available in this setting$429.01RVU23A
2022-10-01Not available in this setting$434.69RVU22D
2022-07-01Not available in this setting$434.69RVU22C
2022-04-01Not available in this setting$434.69RVU22B
2022-01-01Not available in this setting$434.69RVU22A
2021-10-01Not available in this setting$440.41RVU21D
2021-07-01Not available in this setting$440.41RVU21C
2021-04-01Not available in this setting$440.41RVU21B
2021-01-01Not available in this setting$440.41RVU21A
2020-10-01Not available in this setting$446.84RVU20D
2020-07-01Not available in this setting$446.84RVU20C
2020-04-01Not available in this setting$446.84RVU20B
2020-01-01Not available in this setting$446.84RVU20A
2019-10-01Not available in this setting$449.36RVU19D
2019-07-01Not available in this setting$449.36RVU19C
2019-04-01Not available in this setting$449.36RVU19B
2019-01-01Not available in this setting$449.36RVU19A
2018-10-01Not available in this setting$442.40RVU18D
2018-07-01Not available in this setting$442.40RVU18C
2018-04-01Not available in this setting$442.40RVU18B
2018-01-01Not available in this setting$442.40RVU18AR1
2017-10-01Not available in this setting$394.37RVU17D
2017-07-01Not available in this setting$394.37RVU17C
2017-04-01Not available in this setting$394.37RVU17B
2017-01-01Not available in this setting$394.37RVU17A
2016-10-01Not available in this setting$346.81RVU16D
2016-07-01Not available in this setting$346.81RVU16C
2016-04-01Not available in this setting$346.81RVU16B
2016-01-01Not available in this setting$346.81RVU16A
2015-10-01Not available in this setting$345.38RVU15D
2015-07-01Not available in this setting$345.38RVU15C
2015-04-01Not available in this setting$343.66RVU15B
2015-01-01Not available in this setting$343.66RVU15A
2014-10-01Not available in this setting$342.57RVU14D
2014-07-01Not available in this setting$342.57RVU14C
2014-04-01Not available in this setting$342.57RVU14B
2014-01-01Not available in this setting$342.57RVU14A
2013-10-01Not available in this setting$330.82RVU13D
2013-07-01Not available in this setting$330.82RVU13C
2013-04-01Not available in this setting$330.82RVU13B
2013-01-01Not available in this setting$330.82RVU13AR

Price 20251 for an earlier date of service

Where the Puerto Rico rate applies

Puerto Rico is a Medicare payment area, not a city. Our Census mapping connects it to 292 cities and communities in Puerto Rico. Some span more than one payment area; confirm with the service ZIP.

  • Aceitunas
  • Adjuntas
  • Aguada
  • Aguadilla
  • Aguas Buenas
  • Aguas Claras
  • Aguilita
  • Aibonito

Browse all communities in Puerto Rico

20251 billing questions

How do I distinguish this from 20250?

Use 20251 for an open biopsy of a cervical or lumbar vertebral body. Code 20250 is for an open thoracic vertebral body biopsy.

Is a needle biopsy reported with this code?

No. A percutaneous trocar or needle approach is distinct from open surgical exposure; consider 20225 when its deep bone biopsy criteria are met.

What documentation supports the open approach?

The operative report should describe surgical exposure of the vertebral body, the cervical or lumbar region and level, and the tissue sampled.

Can modifier 50 be reported?

No. CMS identifies bilateral adjustment as inappropriate for this code.

How are other procedures in the same session paid?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and the others at 50%. Related postoperative visits for 10 days are included in this code's global period.

Can an assistant or co-surgeon be billed?

Assistant-at-surgery payment may be made. Co-surgeons and team surgery are not permitted for this code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 20251PPRRVU2026_Oct_nonQPP.csv, line 1,740 (RVU26D)
Geographic factors for Puerto RicoGPCI2026.csv, line 91 (RVU26D)

Open CMS sourceHow we calculate rates

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