CPT code 27330: Knee biopsy, open synovial tissue sampling2026 Medicare rate & RVUs in Puerto Rico

In Puerto Rico, Medicare pays $414.62 for 27330 in a facility. There’s no office rate.

Check a contract rate as a % of Medicare · 27330 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 27330 covers

27330 represents open entry into the knee joint to obtain a sample of the synovial lining for diagnostic evaluation. An orthopedic surgeon may perform it when persistent, unexplained synovitis or another abnormal joint-lining change requires tissue examination, including evaluation for inflammatory or infectious disease. The specimen may be sent for histology or other laboratory analysis. This is an open biopsy, not an arthroscopic sampling procedure or removal of the joint lining.

Report the code when the operative service includes an arthrotomy to take a biopsy; the operative note should identify the knee, the abnormal tissue sampled, and the biopsy performed. The 90-day global period includes the day-before preoperative visit and 90 days of related postoperative care. When multiple procedures are performed in one session, the highest-valued procedure is paid in full and other procedures receive the standard multiple-procedure reduction. For bilateral procedures, modifier 50 is paid at 150%. Assistant-at-surgery payment is restricted, co-surgeon payment requires supporting documentation, and team surgery is not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Puerto Rico compares for 27330

Across 109 of 109 payment localities, the facility rate for 27330 runs from $365.78 in Arkansas to $507.71 in San Benito County, CA. Puerto Rico pays $414.62. The RVUs are the same everywhere; the geographic indexes change the dollars.

Every other payment area

27330 rates by state

Office rate range in each state. Select a state to see its payment localities.

See 27330 in every payment locality

How the 27330 rate is calculated

Each of 27330’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 27330

27330 has a 90-day global period: related visits in that window are included in the surgery payment.

What modifiers do to the payment

When to use modifier 50

Codes related to 27330

Related codes aren’t interchangeable: bill the code that matches the service performed.

How 27330 has changed in Puerto Rico

Price 27330 for an earlier date of service

Where the Puerto Rico rate applies

Puerto Rico is a Medicare payment area, not a city. Our Census mapping connects it to 292 cities and communities in Puerto Rico. Some span more than one payment area; confirm with the service ZIP.

• Aceitunas
• Adjuntas
• Aguada
• Aguadilla
• Aguas Buenas
• Aguas Claras
• Aguilita
• Aibonito

Browse all communities in Puerto Rico

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates