CPT code 32561: Pleural fibrinolysis, initial day2026 Medicare rate & RVUs

Reports initial-day instillation of a fibrinolytic through a chest tube or catheter to help clear a loculated pleural fluid collection.

CMS RVU26DEffective Oct 1, 2026109 payment localities4.5K Medicare services in 2024

Medicare pays $101.20 for 32561 nationally in the office and $60.12 in a hospital or facility. Local office rates run $91.62–$126.32.

Medicare rate · 32561

Pleural fibrinolysis, initial day

Office or facility?

Work RVUs
1.36
Total RVUs
3.03
Global days
000

National rate · 2026

$101.20

Office setting, before claim adjustments.

See every locality for 32561 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 32561 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 32561 covers

A physician or other qualified practitioner instills a fibrinolytic agent, such as alteplase, through a chest tube or pleural catheter to help break down fibrin in a loculated pleural collection. This treatment may be used for a complex effusion or empyema when fluid is divided by fibrinous septations. It is performed in settings where the patient can receive care through the pleural drain; the code describes the instillation, not placement of the tube or catheter.

Report 32561 for the initial treatment day. For a later treatment day, use the subsequent-day code 32562 rather than reporting another initial-day service. Documentation should identify the pleural indication, the fibrinolytic administered, the catheter route, and the treatment date. The service has a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures occur in the same session, the highest-valued is paid in full and the others at 50%. Modifier 50 is inappropriate. An assistant at surgery may be paid; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 32561 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$91.62 to $126.32

$91.62$108.97$126.32
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

32561 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$92.68$56.74
Alaska$124.97$81.21
Arizona$98.91$59.10
Arkansas$91.62$56.33
Atlanta, GA$103.16$61.42
Austin, TX$103.67$60.20
Bakersfield, CA$104.98$59.96
Baltimore area, MD$106.83$62.74
Beaumont, TX$96.28$58.89
Brazoria, TX$100.01$59.30

32561 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$91.62

$124.97

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
32561 office rate range by state
State / territoryOffice rate rangeLocalities
AK$124.971
AL$92.681
AR$91.621
AZ$98.911
CA$104.53–$126.3229
CO$103.901
CT$107.071
DC$113.261
DE$100.321
FL$101.49–$110.953
GA$96.68–$103.162
GU$106.051
HI$106.051
IA$93.871
ID$94.501
IL$99.61–$108.264
IN$94.921
KS$93.851
KY$95.141
LA$95.16–$98.892
MA$103.61–$112.372
MD$101.86–$113.263
ME$95.25–$98.902
MI$97.43–$102.862
MN$99.151
MO$94.07–$98.783
MS$92.841
MT$101.191
NC$95.991
ND$98.231
NE$94.181
NH$102.661
NJ$108.18–$112.532
NM$98.001
NV$100.421
NY$97.18–$118.005
OH$96.831
OK$94.661
OR$99.51–$106.282
PA$96.77–$105.072
PR$101.691
RI$103.201
SC$96.591
SD$97.881
TN$94.271
TX$96.28–$103.678
UT$97.651
VA$98.87–$113.262
VI$101.691
VT$98.221
WA$103.29–$114.082
WI$95.611
WV$96.711
WY$99.901

How the 32561 rate is calculated

Each of 32561’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 32561

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.36

1.36 RVUs× 1.000 GPCI

Practice expense1.52

1.52 RVUs× 1.000 GPCI

Malpractice0.15

0.15 RVUs× 1.000 GPCI

Adjusted RVUs

3.0300

Conversion factor

$33.4009

Medicare rate

$101.20

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 32561

The CMS indicators that decide how 32561 is paid alongside other services.

CMS payment indicators · 32561

Pleural fibrinolysis, initial day

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)2Paid.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

32561 without 51 · national office

$101.20

Pleural fibrinolysis, initial day

32561-51 · Second procedure: 50%

$50.60

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

32561 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 32561

    Pleural fibrinolysis, initial day1.36 wRVU

    $101.20

  • 32562

    Pleural fibrinolysis, subsequent day1.21 wRVU

    $91.85−$9.35

  • 32560

    Chemical pleurodesis, via chest tube or catheter1.5 wRVU

    $276.23+$175.03

  • 32555

    Thoracentesis, with imaging guidance2.21 wRVU

    $310.96+$209.76

How to choose

32562Pleural fibrinolysisSubsequent day
32561 identifies the initial treatment day; 32562 is for a subsequent treatment day.
32560Chemical pleurodesisVia chest tube or catheter
32560 is pleurodesis treatment intended to create pleural adhesion. 32561 instills a fibrinolytic to break down fibrin in a pleural collection.
32555ThoracentesisWith imaging guidance
32555 reports image-guided aspiration of pleural fluid. 32561 reports fibrinolytic instillation through a chest tube or catheter.

32561 billing questions

When should 32561 be used instead of 32562?

Use 32561 for the initial day of pleural fibrinolytic treatment. Use 32562 for treatment on a subsequent day.

Does 32561 include placing the chest tube?

No. It reports fibrinolytic instillation through a chest tube or catheter, not insertion of that access device.

What should the record support?

Document the pleural condition being treated, the fibrinolytic agent, its administration through the drain, and whether this is the initial or a subsequent treatment day.

Can modifier 50 be reported?

No. CMS identifies bilateral adjustment as inappropriate for this code.

How does the 0-day global period affect billing?

Same-day preoperative and postoperative care is included in the procedure. Care on a later date is outside that 0-day global period.

Can an assistant or another surgeon be reported?

An assistant at surgery may be paid. Co-surgeons and team surgery are not permitted for this code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 32561PPRRVU2026_Oct_nonQPP.csv, line 3,738 (RVU26D)

Open CMS sourceHow we calculate rates

Did this answer your question about what 32561 pays?

Tell us what you were actually trying to work out. We’ll answer you directly, or build the page that does.

Fee sheets · Coming soon

Put 32561 and the rest of your codes on one sheet

Your codes at your locality, with payer contracts beside Medicare.

Join the waitlist