CPT code 38206: Stem cell collection, autologous, blood-derived2026 Medicare rate & RVUs

Reports collection of a patient’s own blood-derived stem cells for transplantation, commonly by apheresis during preparation for an autologous transplant.

CMS RVU26DEffective Oct 1, 2026109 payment localities3.3K Medicare services in 2024

Medicare pays $67.47 for 38206 nationally in a facility.

Medicare rate · 38206

Stem cell collection, autologous, blood-derived

Office or facility?

Work RVUs
1.46
Total RVUs
2.02
Global days
000

National rate · 2026

$67.47

Facility setting, before claim adjustments.

See every locality for 38206 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 38206 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 38206 covers

This service represents collection of a patient’s own blood-derived stem cells for a planned transplant. Collection commonly occurs by apheresis in a hospital or outpatient collection unit after the transplant team arranges mobilization of cells into the bloodstream. A transplant physician, hematologist, or apheresis team may be involved. This is distinct from harvesting marrow directly from bone.

Report 38206 per collection, with documentation identifying the patient’s own cells, the transplant purpose, and the collection session. CMS restricts payment to specific circumstances. The code has a 0-day global period, so same-day preoperative and postoperative care is included. For multiple procedures in the same session, the highest-valued procedure is paid in full and others receive the standard multiple-procedure reduction. Modifier 50 is inappropriate. Assistant-at-surgery payment requires documented medical necessity; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 38206 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

38206 office and facility rates by payment locality
Payment localityOfficeFacility
AlabamaUnavailable$64.20
AlaskaUnavailable$91.52
ArizonaUnavailable$66.55
ArkansasUnavailable$63.80
Atlanta, GAUnavailable$68.47
Austin, TXUnavailable$68.14
Bakersfield, CAUnavailable$68.73
Baltimore area, MDUnavailable$70.11
Beaumont, TXUnavailable$65.84
Brazoria, TXUnavailable$67.06

38206 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
38206 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

How the 38206 rate is calculated

Each of 38206’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 38206

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.46

1.46 RVUs× 1.000 GPCI

Practice expense0.47

0.47 RVUs× 1.000 GPCI

Malpractice0.09

0.09 RVUs× 1.000 GPCI

Adjusted RVUs

2.0200

Conversion factor

$33.4009

Medicare rate

$67.47

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 38206

The CMS indicators that decide how 38206 is paid alongside other services.

CMS payment indicators · 38206

Stem cell collection, autologous, blood-derived

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

38206 without 51 · national facility

$67.47

Stem cell collection, autologous, blood-derived

38206-51 · Second procedure: 50%

$33.74

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

38206 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • 38206

    Stem cell collection, autologous, blood-derived1.46 wRVU

    Not priced

  • 38205

    Stem cell collection, allogeneic, blood-derived1.46 wRVU

    Not priced

  • 38232

    Bone marrow harvest, autologous transplant harvest3.41 wRVU

    Not priced

  • 38225

    CAR-T cell collection, blood-derived T lymphocytes1.89 wRVU

    Not priced

  • 38207

    Stem cell cryopreservation, freezing-based preservation0.87 wRVU

    Not priced

How to choose

38205Stem cell collectionAllogeneic, blood-derived
Use 38206 for the patient’s own blood-derived cells; use 38205 when the cells come from an allogeneic donor.
38232Bone marrow harvestAutologous transplant harvest
38232 represents harvesting autologous marrow directly. 38206 represents collecting the patient’s blood-derived cells, commonly through apheresis.
38225CAR-T cell collectionBlood-derived T lymphocytes
38225 covers collection of blood-derived T lymphocytes for CAR-T therapy. 38206 is for autologous stem-cell collection for transplantation.
38207Stem cell cryopreservationFreezing-based preservation
38207 represents cryopreservation of stem cells, a processing service; 38206 represents the collection itself.

38206 billing questions

How is 38206 different from 38205?

38206 is for collecting the patient’s own blood-derived cells. Use 38205 when the blood-derived cells come from an allogeneic donor.

Is 38206 reported per collection day or per transplant?

It is reported per collection, not per transplant. Documentation should support each collection billed.

Does 38206 describe a bone marrow harvest?

No. It describes blood-derived cell collection, commonly by apheresis. Autologous marrow harvest is represented by 38232.

Can stem-cell processing be reported separately?

38207 identifies cryopreservation, a processing service rather than collection. Report it when that service is performed and documentation supports it.

Can modifier 50 or an assistant-at-surgery claim be used?

Modifier 50 is inappropriate for 38206. Assistant-at-surgery payment requires documentation of medical necessity.

What documentation supports payment?

Document that the collected cells are the patient’s own blood-derived cells, the transplant purpose, and the collection session. CMS restricts payment to specific circumstances.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 38206PPRRVU2026_Oct_nonQPP.csv, line 4,712 (RVU26D)

Open CMS sourceHow we calculate rates

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