CPT code 38222: Bone marrow exam, aspiration and biopsy2026 Medicare rate & RVUs in Virginia
Reports diagnostic bone marrow aspiration and core biopsy performed in the same session, commonly to evaluate unexplained cytopenias, suspected marrow disease, or hematologic malignancy.
In Virginia, Medicare pays $173.61 for 38222 in the office and $60.99 when it’s performed in a hospital or facility.
Check a contract rate as a % of Medicare · 38222 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What 38222 covers
This code covers obtaining a bone marrow aspirate and a core biopsy for diagnostic evaluation during the same session. Hematologists, oncologists, and other qualified clinicians commonly perform the sampling, often from the posterior iliac crest, in an office procedure room, hospital, or outpatient facility. The samples can help evaluate unexplained anemia or other cytopenias, suspected marrow disorders, and hematologic malignancies.
Report this code when both aspiration and biopsy are performed; use 38220 for aspiration alone and 38221 for biopsy alone. Document the indication, sampling site or sites, and performance of both techniques. CMS applies the standard multiple procedure reduction when applicable procedures are performed in the same session: the highest-valued procedure is paid in full and other procedures at 50%. For a bilateral procedure reported with modifier 50, CMS pays 150%.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How Virginia compares for 38222
Across 109 of 109 payment localities, the office rate for 38222 runs from $157.16 in Arkansas to $235.81 in San Benito County, CA. Virginia pays $173.61. The RVUs are the same everywhere; the geographic indexes change the dollars.
- Virginia · this page$173.61
- Los Angeles, CA · California$200.53+$26.92
- Washington, DC area · District of Columbia$202.45+$28.84
- Miami, FL · Florida$188.83+$15.22
- Chicago, IL · Illinois$183.60+$9.99
- Manhattan, NY · New York$202.96+$29.35
- Alaska · Alaska$206.64+$33.03
Other areas in Virginia first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| AlabamaAlabama | $159.40 | $59.16 |
| ArkansasArkansas | $157.16 | $58.75 |
| ArizonaArizona | $172.50 | $61.48 |
| Bakersfield, CACalifornia | $188.30 | $62.74 |
| Chico, CACalifornia | $187.89 | $62.33 |
| El Centro, CACalifornia | $187.92 | $62.35 |
| Fresno, CACalifornia | $187.89 | $62.33 |
| Hanford, CACalifornia | $187.89 | $62.33 |
| Madera, CACalifornia | $187.89 | $62.33 |
| Merced, CACalifornia | $187.89 | $62.33 |
| Modesto, CACalifornia | $187.89 | $62.33 |
| Napa, CACalifornia | $217.88 | $66.88 |
| Oxnard, CACalifornia | $199.61 | $64.20 |
| Redding, CACalifornia | $187.89 | $62.33 |
| Rest of CaliforniaCalifornia | $187.89 | $62.33 |
| Riverside, CACalifornia | $189.32 | $63.75 |
| Sacramento, CACalifornia | $197.22 | $63.98 |
| Salinas, CACalifornia | $196.48 | $63.70 |
| San Diego, CACalifornia | $201.12 | $64.10 |
| Marin County, CACalifornia | $230.75 | $69.21 |
| San Francisco, CACalifornia | $230.60 | $69.06 |
| San Benito County, CACalifornia | $235.81 | $70.61 |
| Santa Clara County, CACalifornia | $235.21 | $70.00 |
| San Luis Obispo, CACalifornia | $193.31 | $62.82 |
| Santa Cruz, CACalifornia | $203.07 | $63.87 |
| Santa Maria, CACalifornia | $197.22 | $63.64 |
| Santa Rosa, CACalifornia | $205.12 | $64.44 |
| Stockton, CACalifornia | $187.89 | $62.33 |
| Vallejo, CACalifornia | $217.66 | $66.67 |
| Visalia, CACalifornia | $187.89 | $62.33 |
| Yuba City, CACalifornia | $187.89 | $62.33 |
| ColoradoColorado | $184.69 | $62.80 |
| ConnecticutConnecticut | $188.57 | $65.18 |
| DelawareDelaware | $175.31 | $62.12 |
| Fort Lauderdale, FLFlorida | $182.17 | $66.12 |
| Rest of FloridaFlorida | $173.67 | $64.14 |
| Atlanta, GAGeorgia | $180.05 | $63.65 |
| Rest of GeorgiaGeorgia | $164.26 | $62.07 |
| Hawaii, Guam, HIHawaii | $192.45 | $62.19 |
| IowaIowa | $163.70 | $58.88 |
| IdahoIdaho | $164.66 | $59.26 |
| East St. Louis, ILIllinois | $171.35 | $65.95 |
| Rest of IllinoisIllinois | $168.51 | $63.92 |
| Suburban Chicago, ILIllinois | $184.10 | $66.45 |
| IndianaIndiana | $165.60 | $59.40 |
| KansasKansas | $162.78 | $59.22 |
| KentuckyKentucky | $162.68 | $60.83 |
| New Orleans, LALouisiana | $170.19 | $62.38 |
| Rest of LouisianaLouisiana | $162.36 | $60.97 |
| Metropolitan Boston, MAMassachusetts | $202.89 | $66.10 |
| Rest of MassachusettsMassachusetts | $183.57 | $62.93 |
| Baltimore area, MDMaryland | $187.99 | $65.07 |
| Rest of MarylandMaryland | $178.65 | $62.71 |
| Rest of MaineMaine | $165.31 | $59.91 |
| Southern Maine, MEMaine | $174.29 | $60.76 |
| Detroit, MIMichigan | $175.60 | $65.04 |
| Rest of MichiganMichigan | $166.63 | $62.03 |
| MinnesotaMinnesota | $177.62 | $59.73 |
| Metropolitan Kansas City, MOMissouri | $169.24 | $61.67 |
| Metropolitan St. Louis, MOMissouri | $170.99 | $61.92 |
| Rest of MissouriMissouri | $159.53 | $60.78 |
| MississippiMississippi | $158.39 | $59.75 |
| MontanaMontana | $177.02 | $62.45 |
| North CarolinaNorth Carolina | $167.02 | $60.13 |
| North DakotaNorth Dakota | $174.45 | $59.88 |
| NebraskaNebraska | $164.63 | $58.88 |
| New HampshireNew Hampshire | $181.64 | $62.38 |
| Northern New JerseyNew Jersey | $200.41 | $67.52 |
| Rest of New JerseyNew Jersey | $190.90 | $65.80 |
| New MexicoNew Mexico | $167.45 | $62.39 |
| NevadaNevada | $176.43 | $61.75 |
| NYC suburbs and Long Island, NYNew York | $207.54 | $71.32 |
| Poughkeepsie and northern NYC suburbs, NYNew York | $192.00 | $66.55 |
| Queens, NYNew York | $204.85 | $69.44 |
| Rest of New YorkNew York | $169.44 | $60.60 |
| OhioOhio | $166.10 | $61.51 |
| OklahomaOklahoma | $162.58 | $60.28 |
| Portland, OROregon | $190.64 | $63.36 |
| Rest of OregonOregon | $175.23 | $61.12 |
| Metropolitan Philadelphia, PAPennsylvania | $183.87 | $64.61 |
| Rest of PennsylvaniaPennsylvania | $166.46 | $61.29 |
| Puerto RicoPuerto Rico | $178.34 | $62.52 |
| Rhode IslandRhode Island | $181.60 | $63.25 |
| South CarolinaSouth Carolina | $166.80 | $60.95 |
| South DakotaSouth Dakota | $174.14 | $59.58 |
| TennesseeTennessee | $163.56 | $59.42 |
| Austin, TXTexas | $183.93 | $62.72 |
| Beaumont, TXTexas | $165.38 | $61.13 |
| Brazoria, TXTexas | $175.31 | $61.78 |
| Dallas, TXTexas | $176.33 | $62.22 |
| Fort Worth, TXTexas | $175.12 | $62.16 |
| Galveston, TXTexas | $175.77 | $62.01 |
| Houston, TXTexas | $178.15 | $64.39 |
| Rest of TexasTexas | $170.18 | $61.46 |
| UtahUtah | $169.03 | $61.34 |
| Virgin Islands, VIUnited States Virgin Islands | $178.34 | $62.52 |
| VermontVermont | $173.62 | $60.20 |
| Rest of WashingtonWashington | $183.27 | $62.63 |
| King County, WAWashington | $207.15 | $66.58 |
| WisconsinWisconsin | $168.73 | $58.98 |
| West VirginiaWest Virginia | $162.40 | $62.84 |
| WyomingWyoming | $175.90 | $61.33 |
38222 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$157.16
$211.85
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $206.64 | 1 |
| AL | $159.40 | 1 |
| AR | $157.16 | 1 |
| AZ | $172.50 | 1 |
| CA | $187.89–$235.81 | 29 |
| CO | $184.69 | 1 |
| CT | $188.57 | 1 |
| DC | $202.45 | 1 |
| DE | $175.31 | 1 |
| FL | $173.67–$188.83 | 3 |
| GA | $164.26–$180.05 | 2 |
| GU | $192.45 | 1 |
| HI | $192.45 | 1 |
| IA | $163.70 | 1 |
| ID | $164.66 | 1 |
| IL | $168.51–$184.10 | 4 |
| IN | $165.60 | 1 |
| KS | $162.78 | 1 |
| KY | $162.68 | 1 |
| LA | $162.36–$170.19 | 2 |
| MA | $183.57–$202.89 | 2 |
| MD | $178.65–$202.45 | 3 |
| ME | $165.31–$174.29 | 2 |
| MI | $166.63–$175.60 | 2 |
| MN | $177.62 | 1 |
| MO | $159.53–$170.99 | 3 |
| MS | $158.39 | 1 |
| MT | $177.02 | 1 |
| NC | $167.02 | 1 |
| ND | $174.45 | 1 |
| NE | $164.63 | 1 |
| NH | $181.64 | 1 |
| NJ | $190.90–$200.41 | 2 |
| NM | $167.45 | 1 |
| NV | $176.43 | 1 |
| NY | $169.44–$207.54 | 5 |
| OH | $166.10 | 1 |
| OK | $162.58 | 1 |
| OR | $175.23–$190.64 | 2 |
| PA | $166.46–$183.87 | 2 |
| PR | $178.34 | 1 |
| RI | $181.60 | 1 |
| SC | $166.80 | 1 |
| SD | $174.14 | 1 |
| TN | $163.56 | 1 |
| TX | $165.38–$183.93 | 8 |
| UT | $169.03 | 1 |
| VA | $173.61–$202.45 | 2 |
| VI | $178.34 | 1 |
| VT | $173.62 | 1 |
| WA | $183.27–$207.15 | 2 |
| WI | $168.73 | 1 |
| WV | $162.40 | 1 |
| WY | $175.90 | 1 |
How the 38222 rate is calculated
Each of 38222’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 38222
RVUs × geographic indexes × conversion factor
Work1.40
1.40 RVUs× 1.000 GPCI
Practice expense3.77
3.77 RVUs× 1.000 GPCI
Malpractice0.13
0.13 RVUs× 1.000 GPCI
Adjusted RVUs
5.3000
Conversion factor
$33.4009
Medicare rate
$177.02
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact Virginia inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
4,724
- Code
- 38222
- Physician work
- 1.40
- Practice expense
- 3.77
- Malpractice
- 0.13
GPCI2026.csv
106
- Locality
- Virginia
- Physician work
- 1.000
- Practice expense
- 0.983
- Malpractice
- 0.706
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 1.40 | × 1.000 | 1.4000 |
| Practice expense | 3.77 | × 0.983 | 3.7059 |
| Malpractice | 0.13 | × 0.706 | 0.0918 |
| Total RVUs | 5.1977 | ||
| Conversion factor | × 33.4009 | ||
Office rate, Virginia$173.61
Office: (1.4 × 1 + 3.77 × 0.983 + 0.13 × 0.706) × $33.4009 = $173.61
Facility: (1.4 × 1 + 0.34 × 0.983 + 0.13 × 0.706) × $33.4009 = $60.99
Payment rules and modifiers for 38222
The CMS indicators that decide how 38222 is paid alongside other services.
CMS payment indicators · 38222
Bone marrow exam, aspiration and biopsy
| Rule | CMS value | What it means |
|---|---|---|
| Global period | XXX | The global surgery concept doesn’t apply. |
| Multiple procedures | 2 | Standard reduction: highest-valued procedure at 100%, others at 50%. |
| Bilateral (modifier 50) | 1 | Bilateral with modifier 50 pays 150% of the fee schedule amount. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 0 | Physician service: no professional/technical split. |
What modifiers do to the payment
Modifier 50 · payment effect
With and without the modifier
38222 without 50 · national office
$177.02
Bone marrow exam, aspiration and biopsy
38222-50 · Bilateral: 150%
$265.53
Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).
How 38222 has changed in Virginia
38222 · Office / nonfacility
$173.61
Effective 2026-10-01
The base rate is $7.27 higher than on 2025-10-01, moving from $166.34 to $173.61 (4.4%).
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
$166.34changed to$173.61
- Conversion factor 32.3465 changed to 33.4009
- Work RVU 1.44 changed to 1.40
- Practice expense RVU 3.66 changed to 3.77
- Work GPCI 1.002 changed to 1.000
- Practice expense GPCI 0.984 changed to 0.983
- Malpractice GPCI 0.755 changed to 0.706
Held through RVU26B, RVU26C, RVU26D.
January 1, 2025
RVU25A
$172.24changed to$166.34
- Conversion factor 33.2875 changed to 32.3465
- Practice expense RVU 3.70 changed to 3.66
- Malpractice RVU 0.12 changed to 0.13
Held through RVU25B, RVU25C, RVU25D.
March 9, 2024
RVU24AR
$169.43changed to$172.24
- Conversion factor 32.7442 changed to 33.2875
Held through RVU24B, RVU24C, RVU24D.
January 1, 2024
RVU24A
$175.28changed to$169.43
- Conversion factor 33.8872 changed to 32.7442
- Practice expense RVU 3.67 changed to 3.70
- Work GPCI 1.000 changed to 1.002
- Practice expense GPCI 0.990 changed to 0.984
- Malpractice GPCI 0.826 changed to 0.755
January 1, 2023
RVU23A
$179.96changed to$175.28
- Conversion factor 34.6062 changed to 33.8872
- Practice expense RVU 3.68 changed to 3.67
- Malpractice RVU 0.11 changed to 0.12
- Practice expense GPCI 0.995 changed to 0.990
- Malpractice GPCI 0.897 changed to 0.826
Held through RVU23B, RVU23C, RVU23D.
January 1, 2022
RVU22A
$180.41changed to$179.96
- Conversion factor 34.8931 changed to 34.6062
- Practice expense RVU 3.65 changed to 3.68
Held through RVU22B, RVU22C, RVU22D.
January 1, 2021
RVU21A
$176.80changed to$180.41
- Conversion factor 36.0896 changed to 34.8931
- Practice expense RVU 3.39 changed to 3.65
- Practice expense GPCI 0.991 changed to 0.995
- Malpractice GPCI 0.903 changed to 0.897
Held through RVU21B, RVU21C, RVU21D.
January 1, 2020
RVU20A
$173.50changed to$176.80
- Conversion factor 36.0391 changed to 36.0896
- Practice expense RVU 3.33 changed to 3.39
- Malpractice RVU 0.10 changed to 0.11
- Practice expense GPCI 0.986 changed to 0.991
- Malpractice GPCI 0.908 changed to 0.903
Held through RVU20B, RVU20C, RVU20D.
January 1, 2019
RVU19A
$172.24changed to$173.50
- Conversion factor 35.9996 changed to 36.0391
- Practice expense RVU 3.30 changed to 3.33
Held through RVU19B, RVU19C, RVU19D.
January 1, 2018
RVU18AR1
No ratechanged to$172.24
Held through RVU18B, RVU18C, RVU18D.
January 1, 2013
RVU13AR
Earliest loaded release: No rate
Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $173.61 | $60.99 | RVU26D |
| 2026-07-01 | $173.61 | $60.99 | RVU26C |
| 2026-04-01 | $173.61 | $60.99 | RVU26B |
| 2026-01-01 | $173.61 | $60.99 | RVU26A |
| 2025-10-01 | $166.34 | $70.54 | RVU25D |
| 2025-07-01 | $166.34 | $70.54 | RVU25C |
| 2025-04-01 | $166.34 | $70.54 | RVU25B |
| 2025-01-01 | $166.34 | $70.54 | RVU25A |
| 2024-10-01 | $172.24 | $72.66 | RVU24D |
| 2024-07-01 | $172.24 | $72.66 | RVU24C |
| 2024-04-01 | $172.24 | $72.66 | RVU24B |
| 2024-03-09 | $172.24 | $72.66 | RVU24AR |
| 2024-01-01 | $169.43 | $71.48 | RVU24A |
| 2023-10-01 | $175.28 | $74.63 | RVU23D |
| 2023-07-01 | $175.28 | $74.63 | RVU23C |
| 2023-04-01 | $175.28 | $74.63 | RVU23B |
| 2023-01-01 | $175.28 | $74.63 | RVU23A |
| 2022-10-01 | $179.96 | $76.66 | RVU22D |
| 2022-07-01 | $179.96 | $76.66 | RVU22C |
| 2022-04-01 | $179.96 | $76.66 | RVU22B |
| 2022-01-01 | $179.96 | $76.66 | RVU22A |
| 2021-10-01 | $180.41 | $77.64 | RVU21D |
| 2021-07-01 | $180.41 | $77.64 | RVU21C |
| 2021-04-01 | $180.41 | $77.64 | RVU21B |
| 2021-01-01 | $180.41 | $77.64 | RVU21A |
| 2020-10-01 | $176.80 | $80.23 | RVU20D |
| 2020-07-01 | $176.80 | $80.23 | RVU20C |
| 2020-04-01 | $176.80 | $80.23 | RVU20B |
| 2020-01-01 | $176.80 | $80.23 | RVU20A |
| 2019-10-01 | $173.50 | $80.04 | RVU19D |
| 2019-07-01 | $173.50 | $80.04 | RVU19C |
| 2019-04-01 | $173.50 | $80.04 | RVU19B |
| 2019-01-01 | $173.50 | $80.04 | RVU19A |
| 2018-10-01 | $172.24 | $79.96 | RVU18D |
| 2018-07-01 | $172.24 | $79.96 | RVU18C |
| 2018-04-01 | $172.24 | $79.96 | RVU18B |
| 2018-01-01 | $172.24 | $79.96 | RVU18AR1 |
| 2017-10-01 | Not in this release | Not in this release | RVU17D |
| 2017-07-01 | Not in this release | Not in this release | RVU17C |
| 2017-04-01 | Not in this release | Not in this release | RVU17B |
| 2017-01-01 | Not in this release | Not in this release | RVU17A |
| 2016-10-01 | Not in this release | Not in this release | RVU16D |
| 2016-07-01 | Not in this release | Not in this release | RVU16C |
| 2016-04-01 | Not in this release | Not in this release | RVU16B |
| 2016-01-01 | Not in this release | Not in this release | RVU16A |
| 2015-10-01 | Not in this release | Not in this release | RVU15D |
| 2015-07-01 | Not in this release | Not in this release | RVU15C |
| 2015-04-01 | Not in this release | Not in this release | RVU15B |
| 2015-01-01 | Not in this release | Not in this release | RVU15A |
| 2014-10-01 | Not in this release | Not in this release | RVU14D |
| 2014-07-01 | Not in this release | Not in this release | RVU14C |
| 2014-04-01 | Not in this release | Not in this release | RVU14B |
| 2014-01-01 | Not in this release | Not in this release | RVU14A |
| 2013-10-01 | Not in this release | Not in this release | RVU13D |
| 2013-07-01 | Not in this release | Not in this release | RVU13C |
| 2013-04-01 | Not in this release | Not in this release | RVU13B |
| 2013-01-01 | Not in this release | Not in this release | RVU13AR |
Where the Virginia rate applies
Virginia is a Medicare payment area, not a city. Our Census mapping connects it to 628 cities and communities in Virginia. Some span more than one payment area; confirm with the service ZIP.
- Abbs Valley
- Abingdon
- Accomac
- Adwolf
- Afton
- Alberta
- Aldie
- Allison Gap
38222 billing questions
When should 38222 be chosen over 38220 or 38221?
Use 38222 when diagnostic aspiration and core biopsy are both performed in the same session. Use 38220 for aspiration alone or 38221 for biopsy alone.
Can 38220 and 38221 also be reported with 38222?
Do not separately report the aspiration-only or biopsy-only code for the same sampling already represented by 38222.
How is bilateral sampling reported?
When the service is performed bilaterally, report modifier 50. CMS pays a bilateral procedure reported with modifier 50 at 150%.
What documentation supports reporting 38222?
Document the diagnostic reason, the sampling site or sites, and that both aspiration and core biopsy were performed.
Are marrow specimen interpretation services included in 38222?
38222 represents the sampling procedure. Bone marrow smear interpretation or surgical pathology examination may be separately represented by codes such as 85097 or 88305 when those services are performed and documented.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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