CPT code 38228: CAR T-cell administration, autologous cells2026 Medicare rate & RVUs in South Dakota

Report this service for administering a patient’s own genetically modified T cells as CAR T-cell therapy, rather than for collecting or preparing the cells.

CMS RVU26DEffective Oct 1, 2026One payment locality

In South Dakota, Medicare pays $314.54 for 38228 in the office and $145.53 when it’s performed in a hospital or facility.

$314.54Office (non-facility)
$145.53Hospital or facility
−1.4%vs the national office rate ($318.98)

Check a contract rate as a % of Medicare · 38228 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 38228 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Dakota
  2. What 38228 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 38228 covers

This code identifies the administration step of autologous chimeric antigen receptor (CAR) T-cell therapy. A patient’s T lymphocytes are collected and modified for treatment, then the resulting cell product is administered back to that patient. Hematologists, oncologists, and other clinicians involved in cellular therapy typically oversee the infusion in a hospital or specialized treatment setting. The code is specific to CAR T-cell administration, not conventional chemotherapy or hematopoietic stem-cell transplantation.

Select the code for the actual administration of the autologous CAR T-cell product. Collection and preparation activities occur at different stages and are represented by separate codes in the CAR T sequence when applicable. Documentation should identify the autologous CAR T product and record that it was administered, including the date and supporting infusion documentation. CMS assigns physician work, practice expense, and malpractice relative values to the service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Dakota compares for 38228

Across 109 of 109 payment localities, the office rate for 38228 runs from $285.83 in Arkansas to $420.65 in San Benito County, CA. South Dakota pays $314.54. The RVUs are the same everywhere; the geographic indexes change the dollars.

38228 in South Dakota vs other payment areas
  1. South Dakota · this page$314.54
  2. Los Angeles, CA · California$359.66+$45.12
  3. Washington, DC area · District of Columbia$362.90+$48.36
  4. Miami, FL · Florida$337.89+$23.35
  5. Chicago, IL · Illinois$329.39+$14.85
  6. Manhattan, NY · New York$363.67+$49.13
  7. Alaska · Alaska$379.87+$65.33

Other areas in South Dakota first, then benchmark localities. Bars start at $0.

Every other payment area

38228 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$289.57$141.68
ArkansasArkansas$285.83$140.65
ArizonaArizona$311.44$147.67
Bakersfield, CACalifornia$338.63$153.40
Chico, CACalifornia$337.94$152.71
El Centro, CACalifornia$337.98$152.74
Fresno, CACalifornia$337.94$152.71
Hanford, CACalifornia$337.94$152.71

38228 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$285.83

$379.87

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
38228 office rate range by state
State / territoryOffice rate rangeLocalities
AK$379.871
AL$289.571
AR$285.831
AZ$311.441
CA$337.94–$420.6529
CO$332.291
CT$338.721
DC$362.901
DE$316.261
FL$313.01–$337.893
GA$297.35–$324.022
GU$345.221
HI$345.221
IA$296.921
ID$298.491
IL$304.29–$330.564
IN$300.061
KS$295.301
KY$294.871
LA$294.31–$307.372
MA$330.47–$363.502
MD$321.98–$362.903
ME$299.49–$314.602
MI$301.39–$316.142
MN$320.431
MO$289.54–$308.813
MS$287.751
MT$318.971
NC$302.361
ND$315.011
NE$298.491
NH$326.841
NJ$343.15–$359.682
NM$302.721
NV$318.081
NY$306.39–$371.205
OH$300.581
OK$294.791
OR$316.15–$342.412
PA$301.22–$330.772
PR$321.211
RI$327.161
SC$301.861
SD$314.541
TN$296.581
TX$299.42–$330.728
UT$305.571
VA$313.41–$362.902
VI$321.211
VT$313.561
WA$329.93–$370.912
WI$305.451
WV$294.071
WY$317.241

See 38228 in every payment locality

How the 38228 rate is calculated

Each of 38228’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 38228

RVUs × geographic indexes × conversion factor

Office or facility?

Work3.00

3.00 RVUs× 1.000 GPCI

Practice expense6.35

6.35 RVUs× 1.000 GPCI

Malpractice0.20

0.20 RVUs× 1.000 GPCI

Adjusted RVUs

9.5500

Conversion factor

$33.4009

Medicare rate

$318.98

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Dakota inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

4,728

Code
38228
Physician work
3.00
Practice expense
6.35
Malpractice
0.20

GPCI2026.csv

94

Locality
South Dakota
Physician work
1.000
Practice expense
1.000
Malpractice
0.336
Office calculation for 38228 in South Dakota
ComponentRVULocality factorAdjusted
Physician work3.00× 1.0003.0000
Practice expense6.35× 1.0006.3500
Malpractice0.20× 0.3360.0672
Total RVUs9.4172
Conversion factor× 33.4009

Office rate, South Dakota$314.54

Office: (3 × 1 + 6.35 × 1 + 0.2 × 0.336) × $33.4009 = $314.54

Facility: (3 × 1 + 1.29 × 1 + 0.2 × 0.336) × $33.4009 = $145.53

Open 38228 in the RVU calculator

Payment rules and modifiers for 38228

38228 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · 38228

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

$318.98

Non-facility (office)
$318.98
Facility
$149.97

Higher because the practice carries its own overhead.

How 38228 has changed in South Dakota

38228 · Office / nonfacility

$314.54

Effective 2026-10-01

The base rate is $38.42 higher than on 2025-10-01, moving from $276.12 to $314.54 (13.9%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $276.12changed to$314.54

    • Conversion factor 32.3465 changed to 33.4009
    • Practice expense RVU 5.46 changed to 6.35
    • Malpractice GPCI 0.382 changed to 0.336

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    No ratechanged to$276.12

    Held through RVU25B, RVU25C, RVU25D.

  3. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D, RVU19A, RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C, RVU20D, RVU21A, RVU21B, RVU21C, RVU21D, RVU22A, RVU22B, RVU22C, RVU22D, RVU23A, RVU23B, RVU23C, RVU23D, RVU24A, RVU24AR, RVU24B, RVU24C, RVU24D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$314.54$145.53RVU26D
2026-07-01$314.54$145.53RVU26C
2026-04-01$314.54$145.53RVU26B
2026-01-01$314.54$145.53RVU26A
2025-10-01$276.12$166.47RVU25D
2025-07-01$276.12$166.47RVU25C
2025-04-01$276.12$166.47RVU25B
2025-01-01$276.12$166.47RVU25A
2024-10-01Not in this releaseNot in this releaseRVU24D
2024-07-01Not in this releaseNot in this releaseRVU24C
2024-04-01Not in this releaseNot in this releaseRVU24B
2024-03-09Not in this releaseNot in this releaseRVU24AR
2024-01-01Not in this releaseNot in this releaseRVU24A
2023-10-01Not in this releaseNot in this releaseRVU23D
2023-07-01Not in this releaseNot in this releaseRVU23C
2023-04-01Not in this releaseNot in this releaseRVU23B
2023-01-01Not in this releaseNot in this releaseRVU23A
2022-10-01Not in this releaseNot in this releaseRVU22D
2022-07-01Not in this releaseNot in this releaseRVU22C
2022-04-01Not in this releaseNot in this releaseRVU22B
2022-01-01Not in this releaseNot in this releaseRVU22A
2021-10-01Not in this releaseNot in this releaseRVU21D
2021-07-01Not in this releaseNot in this releaseRVU21C
2021-04-01Not in this releaseNot in this releaseRVU21B
2021-01-01Not in this releaseNot in this releaseRVU21A
2020-10-01Not in this releaseNot in this releaseRVU20D
2020-07-01Not in this releaseNot in this releaseRVU20C
2020-04-01Not in this releaseNot in this releaseRVU20B
2020-01-01Not in this releaseNot in this releaseRVU20A
2019-10-01Not in this releaseNot in this releaseRVU19D
2019-07-01Not in this releaseNot in this releaseRVU19C
2019-04-01Not in this releaseNot in this releaseRVU19B
2019-01-01Not in this releaseNot in this releaseRVU19A
2018-10-01Not in this releaseNot in this releaseRVU18D
2018-07-01Not in this releaseNot in this releaseRVU18C
2018-04-01Not in this releaseNot in this releaseRVU18B
2018-01-01Not in this releaseNot in this releaseRVU18AR1
2017-10-01Not in this releaseNot in this releaseRVU17D
2017-07-01Not in this releaseNot in this releaseRVU17C
2017-04-01Not in this releaseNot in this releaseRVU17B
2017-01-01Not in this releaseNot in this releaseRVU17A
2016-10-01Not in this releaseNot in this releaseRVU16D
2016-07-01Not in this releaseNot in this releaseRVU16C
2016-04-01Not in this releaseNot in this releaseRVU16B
2016-01-01Not in this releaseNot in this releaseRVU16A
2015-10-01Not in this releaseNot in this releaseRVU15D
2015-07-01Not in this releaseNot in this releaseRVU15C
2015-04-01Not in this releaseNot in this releaseRVU15B
2015-01-01Not in this releaseNot in this releaseRVU15A
2014-10-01Not in this releaseNot in this releaseRVU14D
2014-07-01Not in this releaseNot in this releaseRVU14C
2014-04-01Not in this releaseNot in this releaseRVU14B
2014-01-01Not in this releaseNot in this releaseRVU14A
2013-10-01Not in this releaseNot in this releaseRVU13D
2013-07-01Not in this releaseNot in this releaseRVU13C
2013-04-01Not in this releaseNot in this releaseRVU13B
2013-01-01Not in this releaseNot in this releaseRVU13AR

Price 38228 for an earlier date of service

Where the South Dakota rate applies

South Dakota is a Medicare payment area, not a city. Our Census mapping connects it to 485 cities and communities in South Dakota. Some span more than one payment area; confirm with the service ZIP.

  • Aberdeen
  • Agar
  • Agency Village
  • Akaska
  • Albee
  • Alcester
  • Alexandria
  • Allen

Browse all communities in South Dakota

38228 billing questions

How is 38228 different from 38227?

38228 identifies administration of the autologous CAR T-cell product. 38227 describes receipt and preparation of the product for administration, a distinct step.

Does 38228 cover cell collection or preparation?

No. It represents administration, not collection of the patient’s T cells or preparation of cells for transport or infusion.

What documentation supports reporting 38228?

Document that the product was autologous CAR T cells and that administration occurred. The infusion record should support the date and service performed.

Is 38228 reported for CAR T-cell collection?

No. Collection is a separate service; 38228 is selected for the later administration of the CAR T-cell product.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 38228PPRRVU2026_Oct_nonQPP.csv, line 4,728 (RVU26D)
Geographic factors for South DakotaGPCI2026.csv, line 94 (RVU26D)

Open CMS sourceHow we calculate rates

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