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CPT code 41100: Tongue biopsy, anterior two-thirds2026 Medicare rate & RVUs in Chicago, IL

Reports tissue sampling from a lesion in the anterior two-thirds of the tongue for microscopic diagnosis, rather than complete lesion removal.

CMS RVU26DEffective Oct 1, 2026One payment locality6.6K Medicare services in 2024

In Chicago, IL, Medicare pays $197.27 for 41100 in the office and $106.30 when it’s performed in a hospital or facility.

$197.27Office (non-facility)
$106.30Hospital or facility
+4.9%vs the national office rate ($188.05)

Check a contract rate as a % of Medicare · 41100 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 41100 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Chicago, IL
  2. What 41100 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 41100 covers

This service samples tissue from the front two-thirds of the tongue, from the tip through the body, for pathologic examination. An otolaryngologist, oral and maxillofacial surgeon, or other qualified clinician may perform it in an office or facility. Common reasons include evaluating a persistent tongue ulcer or a suspicious white or red mucosal patch. The biopsy obtains diagnostic tissue; it is not reported in place of an excision that removes the lesion.

Document the exact tongue site, the clinical concern, and the tissue obtained for examination. Choose the posterior-tongue biopsy code when the sampled site is in the back third, and use a floor-of-mouth code for tissue from that separate site. Medicare assigns a 10-day global period, so related postoperative visits during that period are included. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and the others at 50%. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this service; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Chicago, IL compares for 41100

Across 109 of 109 payment localities, the office rate for 41100 runs from $165.85 in Arkansas to $250.11 in San Benito County, CA. Chicago, IL pays $197.27. The RVUs are the same everywhere; the geographic indexes change the dollars.

41100 in Chicago, IL vs other payment areas
  1. Chicago, IL · this page$197.27
  2. East St. Louis, IL · Illinois$183.63−$13.64
  3. Rest of Illinois · Illinois$179.82−$17.45
  4. Suburban Chicago, IL · Illinois$196.93−$0.34
  5. Los Angeles, CA · California$212.62+$15.35
  6. Washington, DC area · District of Columbia$215.39+$18.12
  7. Miami, FL · Florida$203.31+$6.04

Other areas in Illinois first, then benchmark localities. Bars start at $0.

Every other payment area

41100 in every other Medicare payment locality
Payment localityOfficeFacility
Manhattan, NYNew York$216.68$111.50
AlaskaAlaska$217.06$120.66
AlabamaAlabama$168.34$89.14
ArkansasArkansas$165.85$88.09
ArizonaArizona$182.93$95.22
Bakersfield, CACalifornia$199.46$100.25
Chico, CACalifornia$198.90$99.70
El Centro, CACalifornia$198.94$99.73

41100 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$165.85

$224.51

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
41100 office rate range by state
State / territoryOffice rate rangeLocalities
AK$217.061
AL$168.341
AR$165.851
AZ$182.931
CA$198.90–$250.1129
CO$195.891
CT$200.741
DC$215.391
DE$186.011
FL$185.27–$203.313
GA$174.62–$191.632
GU$203.951
HI$203.951
IA$172.691
ID$173.851
IL$179.82–$197.274
IN$174.891
KS$171.881
KY$172.461
LA$172.19–$180.912
MA$194.68–$215.552
MD$189.61–$215.393
ME$174.80–$184.482
MI$177.07–$187.652
MN$187.511
MO$169.17–$181.553
MS$167.541
MT$188.031
NC$176.671
ND$184.281
NE$173.661
NH$192.811
NJ$202.98–$213.082
NM$178.071
NV$187.121
NY$179.38–$222.075
OH$176.301
OK$172.121
OR$185.62–$202.212
PA$176.58–$195.662
PR$189.441
RI$192.711
SC$176.791
SD$183.831
TN$172.771
TX$175.39–$195.288
UT$179.261
VA$183.88–$215.392
VI$189.441
VT$183.561
WA$194.32–$219.972
WI$177.961
WV$173.021
WY$186.401

See 41100 in every payment locality

How the 41100 rate is calculated

Each of 41100’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 41100

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.38

1.38 RVUs× 1.000 GPCI

Practice expense4.06

4.06 RVUs× 1.000 GPCI

Malpractice0.19

0.19 RVUs× 1.000 GPCI

Adjusted RVUs

5.6300

Conversion factor

$33.4009

Medicare rate

$188.05

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Chicago, IL inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

4,895

Code
41100
Physician work
1.38
Practice expense
4.06
Malpractice
0.19

GPCI2026.csv

48

Locality
Chicago, IL
Physician work
1.007
Practice expense
1.005
Malpractice
2.295
Office calculation for 41100 in Chicago, IL
ComponentRVULocality factorAdjusted
Physician work1.38× 1.0071.3897
Practice expense4.06× 1.0054.0803
Malpractice0.19× 2.2950.4360
Total RVUs5.9060
Conversion factor× 33.4009

Office rate, Chicago, IL$197.27

Office: (1.38 × 1.007 + 4.06 × 1.005 + 0.19 × 2.295) × $33.4009 = $197.27

Facility: (1.38 × 1.007 + 1.35 × 1.005 + 0.19 × 2.295) × $33.4009 = $106.30

Open 41100 in the RVU calculator

Payment rules and modifiers for 41100

41100 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 41100

Tongue biopsy, anterior two-thirds

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 41100

Tongue biopsy, anterior two-thirds

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

41100 without 51 · national office

$188.05

Tongue biopsy, anterior two-thirds

41100-51 · Second procedure: 50%

$94.03

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

Codes related to 41100

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 41100
CodeHow it relatesOffice range, Chicago, IL
Same family
41105Tongue biopsy, posterior one-thirdBiopsy code for a site in the posterior third of the tongue.$199.04
Used instead
41108Oral biopsy, floor of mouthApplies when the sampled tissue is from the floor of the mouth, not the tongue.$177.40
41110Tongue lesion excision, without closureTongue-lesion excision code when tissue is removed rather than sampled for diagnosis.$237.08
41112Tongue excision, anterior two-thirds, with closureTongue-lesion excision option; distinguish lesion removal from diagnostic biopsy.$360.63
Often billed with
88305Tissue pathology exam, level IV specimenMay be reported for the laboratory's histopathologic examination of the biopsy specimen.$71.40

How 41100 has changed in Chicago, IL

41100 · Office / nonfacility

$197.27

Effective 2026-10-01

The base rate is $7.24 higher than on 2025-10-01, moving from $190.03 to $197.27 (3.8%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $190.03changed to$197.27

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.42 changed to 1.38
    • Practice expense RVU 3.99 changed to 4.06
    • Malpractice RVU 0.18 changed to 0.19
    • Practice expense GPCI 1.023 changed to 1.005
    • Malpractice GPCI 2.018 changed to 2.295

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $197.94changed to$190.03

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 4.04 changed to 3.99
    • Malpractice RVU 0.19 changed to 0.18

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $194.71changed to$197.94

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $202.85changed to$194.71

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 4.05 changed to 4.04
    • Work GPCI 1.009 changed to 1.007
    • Practice expense GPCI 1.033 changed to 1.023
    • Malpractice GPCI 1.945 changed to 2.018

  5. January 1, 2023

    RVU23A

    $207.22changed to$202.85

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 4.02 changed to 4.05
    • Work GPCI 1.011 changed to 1.009
    • Practice expense GPCI 1.044 changed to 1.033
    • Malpractice GPCI 1.871 changed to 1.945

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $204.36changed to$207.22

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 3.93 changed to 4.02
    • Malpractice RVU 0.17 changed to 0.19

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $191.53changed to$204.36

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 3.40 changed to 3.93
    • Malpractice RVU 0.18 changed to 0.17
    • Work GPCI 1.009 changed to 1.011
    • Practice expense GPCI 1.039 changed to 1.044
    • Malpractice GPCI 1.898 changed to 1.871

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $189.50changed to$191.53

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 3.31 changed to 3.40
    • Malpractice RVU 0.21 changed to 0.18
    • Work GPCI 1.008 changed to 1.009
    • Practice expense GPCI 1.034 changed to 1.039
    • Malpractice GPCI 1.925 changed to 1.898

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $185.20changed to$189.50

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 3.20 changed to 3.31

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $186.16changed to$185.20

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 3.22 changed to 3.20
    • Work GPCI 1.012 changed to 1.008
    • Practice expense GPCI 1.036 changed to 1.034
    • Malpractice GPCI 1.972 changed to 1.925

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $188.60changed to$186.16

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 3.26 changed to 3.22
    • Malpractice RVU 0.22 changed to 0.21
    • Work GPCI 1.016 changed to 1.012
    • Practice expense GPCI 1.037 changed to 1.036
    • Malpractice GPCI 2.019 changed to 1.972

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $188.91changed to$188.60

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 3.25 changed to 3.26

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $187.97changed to$188.91

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $187.90changed to$187.97

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 3.26 changed to 3.25
    • Malpractice RVU 0.19 changed to 0.22
    • Work GPCI 1.023 changed to 1.016
    • Practice expense GPCI 1.044 changed to 1.037
    • Malpractice GPCI 2.048 changed to 2.019

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $192.62changed to$187.90

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 3.60 changed to 3.26
    • Malpractice RVU 0.20 changed to 0.19
    • Work GPCI 1.030 changed to 1.023
    • Practice expense GPCI 1.051 changed to 1.044
    • Malpractice GPCI 2.077 changed to 2.048

    Held through RVU14B, RVU14C, RVU14D.

  16. October 1, 2013

    RVU13D

    No ratechanged to$192.62

  17. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$197.27$106.30RVU26D
2026-07-01$197.27$106.30RVU26C
2026-04-01$197.27$106.30RVU26B
2026-01-01$197.27$106.30RVU26A
2025-10-01$190.03$112.93RVU25D
2025-07-01$190.03$112.93RVU25C
2025-04-01$190.03$112.93RVU25B
2025-01-01$190.03$112.93RVU25A
2024-10-01$197.94$115.87RVU24D
2024-07-01$197.94$115.87RVU24C
2024-04-01$197.94$115.87RVU24B
2024-03-09$197.94$115.87RVU24AR
2024-01-01$194.71$113.98RVU24A
2023-10-01$202.85$117.43RVU23D
2023-07-01$202.85$117.43RVU23C
2023-04-01$202.85$117.43RVU23B
2023-01-01$202.85$117.43RVU23A
2022-10-01$207.22$118.34RVU22D
2022-07-01$207.22$118.34RVU22C
2022-04-01$207.22$118.34RVU22B
2022-01-01$207.22$118.34RVU22A
2021-10-01$204.36$117.29RVU21D
2021-07-01$204.36$117.29RVU21C
2021-04-01$204.36$117.29RVU21B
2021-01-01$204.36$117.29RVU21A
2020-10-01$191.53$117.28RVU20D
2020-07-01$191.53$117.28RVU20C
2020-04-01$191.53$117.28RVU20B
2020-01-01$191.53$117.28RVU20A
2019-10-01$189.50$119.81RVU19D
2019-07-01$189.50$119.81RVU19C
2019-04-01$189.50$119.81RVU19B
2019-01-01$189.50$119.81RVU19A
2018-10-01$185.20$120.43RVU18D
2018-07-01$185.20$120.43RVU18C
2018-04-01$185.20$120.43RVU18B
2018-01-01$185.20$120.43RVU18AR1
2017-10-01$186.16$122.21RVU17D
2017-07-01$186.16$122.21RVU17C
2017-04-01$186.16$122.21RVU17B
2017-01-01$186.16$122.21RVU17A
2016-10-01$188.60$124.00RVU16D
2016-07-01$188.60$124.00RVU16C
2016-04-01$188.60$124.00RVU16B
2016-01-01$188.60$124.00RVU16A
2015-10-01$188.91$124.44RVU15D
2015-07-01$188.91$124.44RVU15C
2015-04-01$187.97$123.82RVU15B
2015-01-01$187.97$123.82RVU15A
2014-10-01$187.90$123.57RVU14D
2014-07-01$187.90$123.57RVU14C
2014-04-01$187.90$123.57RVU14B
2014-01-01$187.90$123.57RVU14A
2013-10-01$192.62$123.61RVU13D
2013-07-01Rate data unavailableRate data unavailableRVU13C
2013-04-01Rate data unavailableRate data unavailableRVU13B
2013-01-01Rate data unavailableRate data unavailableRVU13AR

Price 41100 for an earlier date of service

Where the Chicago, IL rate applies

Chicago, IL is a Medicare payment area, not a city. Our Census mapping connects it to 137 cities and communities in Illinois. Some span more than one payment area; confirm with the service ZIP.

Browse all communities in Illinois

41100 billing questions

How does 41100 differ from 41105?

41100 is for sampling the anterior two-thirds of the tongue. Use 41105 when the biopsy site is in the posterior third.

Should 41100 be used when the entire lesion is removed?

No. This code describes diagnostic tissue sampling; select the applicable tongue-lesion excision code when the lesion is removed.

Can the pathology examination be billed separately?

The tissue examination is a separate laboratory service when performed and reported by the laboratory. The biopsy claim represents the clinician's sampling procedure.

Is modifier 50 appropriate for biopsies on both sides of the tongue?

No. CMS identifies bilateral adjustment as inappropriate for this code.

How are other procedures in the same session paid?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and the remaining procedures at 50%. Related postoperative visits are included for 10 days.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 41100PPRRVU2026_Oct_nonQPP.csv, line 4,895 (RVU26D)
Geographic factors for Chicago, ILGPCI2026.csv, line 48 (RVU26D)

Open CMS sourceHow we calculate rates

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