CPT code 41100: Tongue biopsy, anterior two-thirds2026 Medicare rate & RVUs in South Carolina

Reports tissue sampling from a lesion in the anterior two-thirds of the tongue for microscopic diagnosis, rather than complete lesion removal.

CMS RVU26DEffective Oct 1, 2026One payment locality6.6K Medicare services in 2024

In South Carolina, Medicare pays $176.79 for 41100 in the office and $93.15 when it’s performed in a hospital or facility.

$176.79Office (non-facility)
$93.15Hospital or facility
−6.0%vs the national office rate ($188.05)

Check a contract rate as a % of Medicare · 41100 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 41100 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Carolina
  2. What 41100 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 41100 covers

This service samples tissue from the front two-thirds of the tongue, from the tip through the body, for pathologic examination. An otolaryngologist, oral and maxillofacial surgeon, or other qualified clinician may perform it in an office or facility. Common reasons include evaluating a persistent tongue ulcer or a suspicious white or red mucosal patch. The biopsy obtains diagnostic tissue; it is not reported in place of an excision that removes the lesion.

Document the exact tongue site, the clinical concern, and the tissue obtained for examination. Choose the posterior-tongue biopsy code when the sampled site is in the back third, and use a floor-of-mouth code for tissue from that separate site. Medicare assigns a 10-day global period, so related postoperative visits during that period are included. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and the others at 50%. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this service; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Carolina compares for 41100

Across 109 of 109 payment localities, the office rate for 41100 runs from $165.85 in Arkansas to $250.11 in San Benito County, CA. South Carolina pays $176.79. The RVUs are the same everywhere; the geographic indexes change the dollars.

41100 in South Carolina vs other payment areas
  1. South Carolina · this page$176.79
  2. Los Angeles, CA · California$212.62+$35.83
  3. Washington, DC area · District of Columbia$215.39+$38.60
  4. Miami, FL · Florida$203.31+$26.52
  5. Chicago, IL · Illinois$197.27+$20.48
  6. Manhattan, NY · New York$216.68+$39.89
  7. Alaska · Alaska$217.06+$40.27

Other areas in South Carolina first, then benchmark localities. Bars start at $0.

Every other payment area

41100 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$168.34$89.14
ArkansasArkansas$165.85$88.09
ArizonaArizona$182.93$95.22
Bakersfield, CACalifornia$199.46$100.25
Chico, CACalifornia$198.90$99.70
El Centro, CACalifornia$198.94$99.73
Fresno, CACalifornia$198.90$99.70
Hanford, CACalifornia$198.90$99.70

41100 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$165.85

$224.51

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
41100 office rate range by state
State / territoryOffice rate rangeLocalities
AK$217.061
AL$168.341
AR$165.851
AZ$182.931
CA$198.90–$250.1129
CO$195.891
CT$200.741
DC$215.391
DE$186.011
FL$185.27–$203.313
GA$174.62–$191.632
GU$203.951
HI$203.951
IA$172.691
ID$173.851
IL$179.82–$197.274
IN$174.891
KS$171.881
KY$172.461
LA$172.19–$180.912
MA$194.68–$215.552
MD$189.61–$215.393
ME$174.80–$184.482
MI$177.07–$187.652
MN$187.511
MO$169.17–$181.553
MS$167.541
MT$188.031
NC$176.671
ND$184.281
NE$173.661
NH$192.811
NJ$202.98–$213.082
NM$178.071
NV$187.121
NY$179.38–$222.075
OH$176.301
OK$172.121
OR$185.62–$202.212
PA$176.58–$195.662
PR$189.441
RI$192.711
SC$176.791
SD$183.831
TN$172.771
TX$175.39–$195.288
UT$179.261
VA$183.88–$215.392
VI$189.441
VT$183.561
WA$194.32–$219.972
WI$177.961
WV$173.021
WY$186.401

See 41100 in every payment locality

How the 41100 rate is calculated

Each of 41100’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 41100

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.38

1.38 RVUs× 1.000 GPCI

Practice expense4.06

4.06 RVUs× 1.000 GPCI

Malpractice0.19

0.19 RVUs× 1.000 GPCI

Adjusted RVUs

5.6300

Conversion factor

$33.4009

Medicare rate

$188.05

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Carolina inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

4,895

Code
41100
Physician work
1.38
Practice expense
4.06
Malpractice
0.19

GPCI2026.csv

93

Locality
South Carolina
Physician work
1.000
Practice expense
0.924
Malpractice
0.850
Office calculation for 41100 in South Carolina
ComponentRVULocality factorAdjusted
Physician work1.38× 1.0001.3800
Practice expense4.06× 0.9243.7514
Malpractice0.19× 0.8500.1615
Total RVUs5.2929
Conversion factor× 33.4009

Office rate, South Carolina$176.79

Office: (1.38 × 1 + 4.06 × 0.924 + 0.19 × 0.85) × $33.4009 = $176.79

Facility: (1.38 × 1 + 1.35 × 0.924 + 0.19 × 0.85) × $33.4009 = $93.15

Open 41100 in the RVU calculator

Payment rules and modifiers for 41100

41100 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 41100

Tongue biopsy, anterior two-thirds

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 41100

Tongue biopsy, anterior two-thirds

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

41100 without 51 · national office

$188.05

Tongue biopsy, anterior two-thirds

41100-51 · Second procedure: 50%

$94.03

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

How 41100 has changed in South Carolina

41100 · Office / nonfacility

$176.79

Effective 2026-10-01

The base rate is $8.27 higher than on 2025-10-01, moving from $168.52 to $176.79 (4.9%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $168.52changed to$176.79

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.42 changed to 1.38
    • Practice expense RVU 3.99 changed to 4.06
    • Malpractice RVU 0.18 changed to 0.19
    • Practice expense GPCI 0.913 changed to 0.924
    • Malpractice GPCI 0.817 changed to 0.850

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $175.22changed to$168.52

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 4.04 changed to 3.99
    • Malpractice RVU 0.19 changed to 0.18

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $172.36changed to$175.22

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $177.60changed to$172.36

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 4.05 changed to 4.04
    • Practice expense GPCI 0.908 changed to 0.913
    • Malpractice GPCI 0.756 changed to 0.817
  5. January 1, 2023

    RVU23A

    $179.33changed to$177.60

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 4.02 changed to 4.05
    • Practice expense GPCI 0.903 changed to 0.908
    • Malpractice GPCI 0.695 changed to 0.756

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $177.50changed to$179.33

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 3.93 changed to 4.02
    • Malpractice RVU 0.17 changed to 0.19

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $166.59changed to$177.50

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 3.40 changed to 3.93
    • Malpractice RVU 0.18 changed to 0.17
    • Practice expense GPCI 0.907 changed to 0.903
    • Malpractice GPCI 0.624 changed to 0.695

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $164.15changed to$166.59

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 3.31 changed to 3.40
    • Malpractice RVU 0.21 changed to 0.18
    • Practice expense GPCI 0.912 changed to 0.907
    • Malpractice GPCI 0.553 changed to 0.624

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $160.36changed to$164.15

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 3.20 changed to 3.31

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $161.13changed to$160.36

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 3.22 changed to 3.20
    • Malpractice GPCI 0.634 changed to 0.553

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $162.92changed to$161.13

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 3.26 changed to 3.22
    • Malpractice RVU 0.22 changed to 0.21
    • Malpractice GPCI 0.715 changed to 0.634

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $163.18changed to$162.92

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 3.25 changed to 3.26

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $162.37changed to$163.18

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $161.46changed to$162.37

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 3.26 changed to 3.25
    • Malpractice RVU 0.19 changed to 0.22
    • Practice expense GPCI 0.911 changed to 0.912
    • Malpractice GPCI 0.618 changed to 0.715

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $163.19changed to$161.46

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 3.60 changed to 3.26
    • Malpractice RVU 0.20 changed to 0.19
    • Practice expense GPCI 0.909 changed to 0.911
    • Malpractice GPCI 0.520 changed to 0.618

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $163.19

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$176.79$93.15RVU26D
2026-07-01$176.79$93.15RVU26C
2026-04-01$176.79$93.15RVU26B
2026-01-01$176.79$93.15RVU26A
2025-10-01$168.52$99.71RVU25D
2025-07-01$168.52$99.71RVU25C
2025-04-01$168.52$99.71RVU25B
2025-01-01$168.52$99.71RVU25A
2024-10-01$175.22$101.97RVU24D
2024-07-01$175.22$101.97RVU24C
2024-04-01$175.22$101.97RVU24B
2024-03-09$175.22$101.97RVU24AR
2024-01-01$172.36$100.31RVU24A
2023-10-01$177.60$102.53RVU23D
2023-07-01$177.60$102.53RVU23C
2023-04-01$177.60$102.53RVU23B
2023-01-01$177.60$102.53RVU23A
2022-10-01$179.33$102.46RVU22D
2022-07-01$179.33$102.46RVU22C
2022-04-01$179.33$102.46RVU22B
2022-01-01$179.33$102.46RVU22A
2021-10-01$177.50$102.19RVU21D
2021-07-01$177.50$102.19RVU21C
2021-04-01$177.50$102.19RVU21B
2021-01-01$177.50$102.19RVU21A
2020-10-01$166.59$101.78RVU20D
2020-07-01$166.59$101.78RVU20C
2020-04-01$166.59$101.78RVU20B
2020-01-01$166.59$101.78RVU20A
2019-10-01$164.15$102.69RVU19D
2019-07-01$164.15$102.69RVU19C
2019-04-01$164.15$102.69RVU19B
2019-01-01$164.15$102.69RVU19A
2018-10-01$160.36$103.23RVU18D
2018-07-01$160.36$103.23RVU18C
2018-04-01$160.36$103.23RVU18B
2018-01-01$160.36$103.23RVU18AR1
2017-10-01$161.13$104.84RVU17D
2017-07-01$161.13$104.84RVU17C
2017-04-01$161.13$104.84RVU17B
2017-01-01$161.13$104.84RVU17A
2016-10-01$162.92$106.11RVU16D
2016-07-01$162.92$106.11RVU16C
2016-04-01$162.92$106.11RVU16B
2016-01-01$162.92$106.11RVU16A
2015-10-01$163.18$106.49RVU15D
2015-07-01$163.18$106.49RVU15C
2015-04-01$162.37$105.96RVU15B
2015-01-01$162.37$105.96RVU15A
2014-10-01$161.46$105.33RVU14D
2014-07-01$161.46$105.33RVU14C
2014-04-01$161.46$105.33RVU14B
2014-01-01$161.46$105.33RVU14A
2013-10-01$163.19$103.50RVU13D
2013-07-01$163.19$103.50RVU13C
2013-04-01$163.19$103.50RVU13B
2013-01-01$163.19$103.50RVU13AR

Price 41100 for an earlier date of service

Where the South Carolina rate applies

South Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 475 cities and communities in South Carolina. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Abney Crossroads
  • Adams Run
  • Aiken
  • Alcolu
  • Allendale
  • Anderson
  • Andrews

Browse all communities in South Carolina

41100 billing questions

How does 41100 differ from 41105?

41100 is for sampling the anterior two-thirds of the tongue. Use 41105 when the biopsy site is in the posterior third.

Should 41100 be used when the entire lesion is removed?

No. This code describes diagnostic tissue sampling; select the applicable tongue-lesion excision code when the lesion is removed.

Can the pathology examination be billed separately?

The tissue examination is a separate laboratory service when performed and reported by the laboratory. The biopsy claim represents the clinician's sampling procedure.

Is modifier 50 appropriate for biopsies on both sides of the tongue?

No. CMS identifies bilateral adjustment as inappropriate for this code.

How are other procedures in the same session paid?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and the remaining procedures at 50%. Related postoperative visits are included for 10 days.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 41100PPRRVU2026_Oct_nonQPP.csv, line 4,895 (RVU26D)
Geographic factors for South CarolinaGPCI2026.csv, line 93 (RVU26D)

Open CMS sourceHow we calculate rates

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