CPT code 41105: Tongue biopsy, posterior one-third2026 Medicare rate & RVUs in Illinois

Reports tissue sampling from the posterior one-third of the tongue to evaluate a suspicious lesion or other abnormal tissue.

CMS RVU26DEffective Oct 1, 20264 payment localities1.3K Medicare services in 2024

Medicare pays $181.40–$199.04 for 41105 in the office in Illinois, from Rest of Illinois to Chicago, IL. Which amount applies depends on the service address.

$181.40–$199.04Office (non-facility)
$100.29–$109.75Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Illinois
  2. What 41105 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 41105 covers

This service is a tissue sample taken from the posterior one-third of the tongue for diagnostic evaluation, such as investigation of a suspicious ulcer, mass, or mucosal change. An otolaryngologist, head-and-neck surgeon, or oral and maxillofacial surgeon may perform it in an office, procedure room, or operating room, depending on access and the patient’s needs. The sample is submitted for pathologic examination; this code describes the biopsy procedure, not the pathology interpretation.

Choose this code for a biopsy from the posterior tongue, rather than the anterior two-thirds or the floor of the mouth. The note should identify the sampled site and the lesion or abnormal tissue prompting the biopsy. It has a 10-day global period, so related postoperative visits during that period are included. When multiple procedures subject to the standard reduction are performed in the same session, the highest-valued is paid in full and the others at 50%. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery, and co-surgeon and team-surgery billing are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 41105 pays more and less in Illinois

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

4 payment localities

$181.40 to $199.04

$181.40$190.22$199.04
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
41105 office and facility rates by payment locality
Payment localityOfficeFacility
Chicago, IL$199.04$109.75
East St. Louis, IL$185.36$103.62
Rest of Illinois$181.40$100.29
Suburban Chicago, IL$198.52$107.27

How the 41105 rate is calculated

Each of 41105’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 41105

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.43

1.43 RVUs× 1.000 GPCI

Practice expense4.04

4.04 RVUs× 1.000 GPCI

Malpractice0.20

0.20 RVUs× 1.000 GPCI

Adjusted RVUs

5.6700

Conversion factor

$33.4009

Medicare rate

$189.38

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 41105

41105 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 41105

Tongue biopsy, posterior one-third

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 41105

Tongue biopsy, posterior one-third

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

41105 without 51 · national office

$189.38

Tongue biopsy, posterior one-third

41105-51 · Second procedure: 50%

$94.69

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

41105 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 41105

    Tongue biopsy, posterior one-third1.43 wRVU

    $189.38

  • 41100

    Tongue biopsy, anterior two-thirds1.38 wRVU

    $188.05−$1.33

  • 41108

    Oral biopsy, floor of mouth1.07 wRVU

    $170.01−$19.37

  • 41110

    Tongue lesion excision, without closure1.52 wRVU

    $226.79+$37.41

How to choose

41100Tongue biopsyAnterior two-thirds
41100 describes biopsy of the anterior two-thirds of the tongue. Use 41105 when the sampled tissue is from the posterior one-third.
41108Oral biopsyFloor of mouth
41108 is for tissue sampled from the floor of the mouth, not the tongue. Select by the documented specimen site.
41110Tongue lesion excisionWithout closure
41105 represents diagnostic sampling of posterior tongue tissue. 41110 is an excision code for removing a tongue lesion without closure.

41105 billing questions

How is 41105 distinguished from 41100?

41105 is for a biopsy of the posterior one-third of the tongue; 41100 is for the anterior two-thirds. The documentation should identify which part of the tongue was sampled.

Can 41105 be used for a floor-of-mouth biopsy?

No. A biopsy of the floor of the mouth is reported with 41108; 41105 is for the posterior tongue.

When would a tongue lesion excision code be more appropriate?

Use a biopsy code when tissue is sampled for diagnosis. When the lesion is removed rather than sampled, consider the applicable tongue lesion excision code, such as 41110.

Is modifier 50 appropriate for a biopsy of both sides of the tongue?

No. CMS identifies bilateral adjustment as inappropriate for this code, so do not append modifier 50.

Are related postoperative visits included?

Yes. Related postoperative visits during the 10-day global period are included in the procedure.

Can an assistant surgeon or co-surgeon be billed?

Medicare does not pay an assistant at surgery for this code. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 41105PPRRVU2026_Oct_nonQPP.csv, line 4,896 (RVU26D)

Open CMS sourceHow we calculate rates

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