CPT code 45346: Flexible sigmoidoscopy, lesion ablation2026 Medicare rate & RVUs

Reports flexible sigmoidoscopy treatment that ablates a colorectal tumor, polyp, or other lesion that is not suited to standard endoscopic removal.

CMS RVU26DEffective Oct 1, 2026109 payment localities984 Medicare services in 2024

Medicare pays $2,492.38 for 45346 nationally in the office and $143.29 in a hospital or facility. Local office rates run $2,149.95–$3,553.33.

Medicare rate · 45346

Flexible sigmoidoscopy, lesion ablation

Office or facility?

Work RVUs
2.74
Total RVUs
74.62
Global days
000

National rate · 2026

$2,492.38

Office setting, before claim adjustments.

See every locality for 45346 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 45346 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 45346 covers

During flexible sigmoidoscopy, the clinician examines the rectum and sigmoid colon and destroys a tumor, polyp, or other lesion endoscopically, such as with laser or electrosurgical energy. This treatment is selected when the lesion is not amenable to removal with hot biopsy forceps, bipolar cautery, or a snare. Gastroenterologists and colorectal surgeons commonly perform it in an endoscopy unit or procedure room.

Report the service when the operative note supports ablation rather than biopsy, snare removal, or another therapeutic technique. Document the lesion treated, its location, the ablation method, and why the chosen approach was used. The 0-day global period includes same-day preoperative and postoperative care. When related endoscopies are performed together, CMS endoscopy-family pricing applies. Do not append modifier 50; this flexible endoscopic treatment is not a bilateral procedure. CMS does not pay an assistant at surgery for this service, and co-surgeon and team-surgery reporting are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 45346 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$2149.95 to $3553.33

$2149.95$2851.64$3553.33
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

45346 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$2,188.76$133.31
Alaska$2,688.35$186.58
Arizona$2,416.67$140.40
Arkansas$2,149.95$132.08
Atlanta, GA$2,533.16$146.49
Austin, TX$2,629.85$144.52
Bakersfield, CA$2,719.07$144.47
Baltimore area, MD$2,670.96$150.40
Beaumont, TX$2,276.51$138.85
Brazoria, TX$2,469.10$141.16

45346 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$2,149.95

$3,135.69

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
45346 office rate range by state
State / territoryOffice rate rangeLocalities
AK$2,688.351
AL$2,188.761
AR$2,149.951
AZ$2,416.671
CA$2,718.05–$3,553.3329
CO$2,643.911
CT$2,680.581
DC$2,923.931
DE$2,463.011
FL$2,392.95–$2,607.713
GA$2,236.49–$2,533.162
GU$2,814.961
HI$2,814.961
IA$2,282.421
ID$2,295.231
IL$2,290.88–$2,566.304
IN$2,312.101
KS$2,257.351
KY$2,226.181
LA$2,217.11–$2,352.942
MA$2,618.18–$2,958.442
MD$2,521.03–$2,923.933
ME$2,296.92–$2,466.682
MI$2,285.95–$2,416.532
MN$2,553.681
MO$2,162.33–$2,377.703
MS$2,157.271
MT$2,492.351
NC$2,328.181
ND$2,485.631
NE$2,301.321
NH$2,588.931
NJ$2,716.97–$2,881.232
NM$2,296.331
NV$2,492.871
NY$2,369.53–$2,959.585
OH$2,284.581
OK$2,234.171
OR$2,479.44–$2,756.172
PA$2,295.81–$2,594.182
PR$2,518.491
RI$2,571.741
SC$2,309.071
SD$2,484.831
TN$2,269.671
TX$2,276.51–$2,629.858
UT$2,347.851
VA$2,448.41–$2,923.932
VI$2,518.491
VT$2,462.871
WA$2,617.49–$3,037.292
WI$2,384.161
WV$2,184.251
WY$2,489.421

How the 45346 rate is calculated

Each of 45346’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 45346

RVUs × geographic indexes × conversion factor

Office or facility?

Work2.74

2.74 RVUs× 1.000 GPCI

Practice expense71.54

71.54 RVUs× 1.000 GPCI

Malpractice0.34

0.34 RVUs× 1.000 GPCI

Adjusted RVUs

74.6200

Conversion factor

$33.4009

Medicare rate

$2,492.38

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 45346

The CMS indicators that decide how 45346 is paid alongside other services.

CMS payment indicators · 45346

Flexible sigmoidoscopy, lesion ablation

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures3Endoscopy family rules apply.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

45346 without 51 · national office

$2,492.38

Flexible sigmoidoscopy, lesion ablation

45346-51 · Second procedure: 50%

$1,246.19

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

45346 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • 45346

    Flexible sigmoidoscopy, lesion ablation2.74 wRVU

    $2,492.38

  • 45333

    Flexible sigmoidoscopy, hot biopsy forceps removal1.51 wRVU

    $368.08−$2,124.30

  • 45338

    Flexible sigmoidoscopy, snare lesion removal2 wRVU

    $335.01−$2,157.37

  • 45330

    Flexible sigmoidoscopy, diagnostic0.82 wRVU

    $215.10−$2,277.28

  • 45349

    Endoscopic mucosal resection, flexible sigmoidoscopy3.43 wRVU

    Not priced

How to choose

45333Flexible sigmoidoscopyHot biopsy forceps removal
45333 is for lesion removal using hot biopsy forceps or bipolar cautery. Choose 45346 when the lesion is ablated rather than removed and is not amenable to those methods.
45338Flexible sigmoidoscopySnare lesion removal
45338 reports lesion removal by snare. Choose 45346 when the treatment is ablation, not snare excision.
45330Flexible sigmoidoscopyDiagnostic
45330 is diagnostic flexible sigmoidoscopy without lesion ablation. When ablation is performed, the therapeutic service distinguishes 45346.
45349Endoscopic mucosal resectionFlexible sigmoidoscopy
45349 reports endoscopic mucosal resection. It differs from 45346, which describes ablation of a lesion rather than mucosal resection.

45346 billing questions

When should this code be chosen instead of a removal code?

Use it when the lesion is ablated rather than removed and is not amenable to hot biopsy forceps, bipolar cautery, or snare removal. The operative note should identify the technique and lesion.

How does this differ from diagnostic flexible sigmoidoscopy?

A diagnostic examination reports the inspection when no ablation is performed. When a lesion is treated by ablation during the examination, report the therapeutic service instead of treating the encounter as diagnostic only.

Can biopsy or another endoscopy be reported on the same date?

CMS endoscopy-family pricing applies when related endoscopies are performed together. Documentation should distinguish any separately performed service; do not report a diagnostic examination merely for the inspection integral to the therapeutic procedure.

Should modifier 50 be appended?

No. This is not a bilateral procedure, so modifier 50 is inappropriate.

What global-period and surgical-assistance rules apply?

The service has a 0-day global period, with same-day preoperative and postoperative care included. CMS does not pay an assistant at surgery, and co-surgeon and team-surgery reporting are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 45346PPRRVU2026_Oct_nonQPP.csv, line 5,509 (RVU26D)

Open CMS sourceHow we calculate rates

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