CPT code 46910: Anal lesion destruction, extensive lesions2026 Medicare rate & RVUs

Medicare pays $296.60 for 46910 nationally in the office and $129.93 in a hospital or facility. Local office rates run $260.09–$397.99.

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 46910 covers

This code represents extensive destruction of lesions on the anus, rather than removal by excision. Typical targets include anal condylomas or papillomas. A colorectal or general surgeon commonly performs the procedure in an office procedure room, ambulatory setting, or operating room, depending on the extent of treatment and the patient’s needs.

Choose this code when the operative or procedure note supports extensive lesion destruction; use the documented treatment method, lesion distribution, and scope to distinguish it from simple destruction or codes naming a specific technique. The note should identify the anal lesions treated and describe the extent of treatment. Medicare assigns a 10-day global period, so related postoperative visits during that period are included. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% multiple-procedure reduction. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this code; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 46910 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

46910 rates by state

Office rate range in each state. Select a state to see its payment localities.

How the 46910 rate is calculated

Each of 46910’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 46910

46910 has a 10-day global period: related visits in that window are included in the surgery payment.

What modifiers do to the payment

When to use modifier 51

46910 compared with similar codes

How to choose

46900Anal lesion destructionSimple lesions

46900 represents simple anal lesion destruction; 46910 is the extensive-destruction code. The documented scope of treatment guides the choice.

46916Anal lesion treatmentCryosurgery, simple lesions

46916 specifically identifies cryosurgery. Choose it when freezing is the documented treatment method, rather than reporting 46910 based only on lesion extent.

46917Anal lesion laserSimple, laser surgery

46917 identifies laser surgery of anal lesions. Use it when laser treatment is performed; 46910 represents extensive destruction without that technique-specific label.

46922Anal lesion excisionOne or more lesions

46922 is for excising anal lesions. Choose 46910 when the lesions are destroyed rather than excised.

Codes related to 46910

Related codes aren’t interchangeable: bill the code that matches the service performed.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates