CPT code 46916: Anal lesion treatment, cryosurgery, simple lesions2026 Medicare rate & RVUs in California

Reports simple destruction of anal lesion(s) by freezing, commonly for anal condylomata, when cryosurgery is the documented treatment method.

CMS RVU26DEffective Oct 1, 202629 payment localities561 Medicare services in 2024

Medicare pays $269.93–$339.85 for 46916 in the office in California, from Chico, CA to San Benito County, CA. Which amount applies depends on the service address.

$269.93–$339.85Office (non-facility)
$125.33–$149.60Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in California
  2. What 46916 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 46916 covers

Code 46916 represents destruction of one or more anal lesions by freezing, most commonly anal condylomata. A colorectal or general surgeon typically applies a cryogenic agent to the lesion or lesions in an office procedure room or a facility setting. The code is distinguished by the cryosurgical method and simple treatment level, rather than extensive destruction.

Report it when the clinician documents cryosurgery and an extent consistent with simple treatment. The record should identify the treated lesion(s), anal site, method, and extent. The 10-day global period includes related postoperative visits during that period. When multiple procedures subject to the standard reduction are performed in one session, the highest-valued procedure is paid in full and the others at 50%. Modifier 50 is inappropriate; assistant-at-surgery payment is barred by statutory restriction, and co-surgeon and team-surgery billing are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 46916 pays more and less in California

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

29 payment localities

$269.93 to $339.85

$269.93$304.89$339.85
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

29 of 29 payment localities

46916 office and facility rates by payment locality
Payment localityOfficeFacility
Bakersfield, CA$270.55$125.95
Chico, CA$269.93$125.33
El Centro, CA$269.97$125.37
Fresno, CA$269.93$125.33
Hanford, CA$269.93$125.33
Los Angeles, CA$288.41$132.33
Madera, CA$269.93$125.33
Marin County, CA$332.47$146.45
Merced, CA$269.93$125.33
Modesto, CA$269.93$125.33

How the 46916 rate is calculated

Each of 46916’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 46916

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.86

1.86 RVUs× 1.000 GPCI

Practice expense5.55

5.55 RVUs× 1.000 GPCI

Malpractice0.20

0.20 RVUs× 1.000 GPCI

Adjusted RVUs

7.6100

Conversion factor

$33.4009

Medicare rate

$254.18

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 46916

46916 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 46916

Anal lesion treatment, cryosurgery, simple lesions

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 46916

Anal lesion treatment, cryosurgery, simple lesions

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

46916 without 51 · national office

$254.18

Anal lesion treatment, cryosurgery, simple lesions

46916-51 · Second procedure: 50%

$127.09

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

46916 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • 46916

    Anal lesion treatment, cryosurgery, simple lesions1.86 wRVU

    $254.18

  • 46900

    Anal lesion destruction, simple lesions1.86 wRVU

    $268.54+$14.36

  • 46910

    Anal lesion destruction, extensive lesions1.86 wRVU

    $296.60+$42.42

  • 46924

    Anal lesion destruction, extensive treatment2.74 wRVU

    $621.59+$367.41

  • 46922

    Anal lesion excision, one or more lesions1.86 wRVU

    $344.36+$90.18

How to choose

46900Anal lesion destructionSimple lesions
Choose 46900 for simple chemical destruction of anal lesions; 46916 is for simple destruction by freezing.
46910Anal lesion destructionExtensive lesions
Choose 46910 for simple electrosurgical destruction. Use 46916 when cryosurgery is the documented method.
46924Anal lesion destructionExtensive treatment
46924 represents extensive anal lesion destruction; 46916 represents simple cryosurgical treatment.
46922Anal lesion excisionOne or more lesions
46922 is for excision, which removes lesion tissue. Code 46916 describes destruction by freezing.

46916 billing questions

How does 46916 differ from 46900 or 46910?

46916 identifies cryosurgery. The neighboring codes distinguish other simple destruction methods, including chemical treatment and electrosurgical treatment.

When should extensive destruction be considered instead?

Use 46924 when the documented destruction is extensive. Code 46916 is for simple treatment by cryosurgery.

Can modifier 50 be reported?

No. The CMS bilateral adjustment does not apply to this code, and modifier 50 is inappropriate.

Are postoperative visits separately reported during the global period?

Related postoperative visits during the 10-day global period are included in the procedure.

How does Medicare apply the multiple-procedure reduction?

For qualifying procedures in the same session, the highest-valued procedure is paid in full and the others at 50%. Assistant-at-surgery payment is restricted, and co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 46916PPRRVU2026_Oct_nonQPP.csv, line 5,632 (RVU26D)

Open CMS sourceHow we calculate rates

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