CPT code 50225: Nephrectomy, complicated removal2026 Medicare rate & RVUs

Reports a complex kidney removal when prior surgery, radiotherapy, or infection makes nephrectomy more difficult than a routine removal.

CMS RVU26DEffective Oct 1, 2026109 payment localities53 Medicare services in 2024

Medicare pays $1,059.48 for 50225 nationally in a facility.

Medicare rate · 50225

Nephrectomy, complicated removal

Office or facility?

Work RVUs
21.33
Total RVUs
31.72
Global days
090

National rate · 2026

$1,059.48

Facility setting, before claim adjustments.

See every locality for 50225 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 50225 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 50225 covers

This code describes a complex nephrectomy, including partial ureter removal when performed as part of the kidney removal. It is used when prior surgery, radiotherapy, or infection complicates the operation; examples include dense operative scarring or an infected kidney. Urologists typically perform the procedure in a hospital operating room. The operative report should identify the complicating condition and explain how it affected the dissection or removal, rather than relying on the diagnosis alone.

Select this code for the complex removal rather than routine nephrectomy when the documented circumstances support the added complexity. CMS assigns a 90-day global period, including the day-before preoperative visit and 90 days of related postoperative care. For multiple procedures in the same session, the highest-valued procedure is paid in full and other procedures at 50%. Bilateral reporting with modifier 50 is paid at 150%. Assistant-at-surgery payment may be available; co-surgeon payment requires supporting documentation, and team surgery is not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 50225 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

50225 office and facility rates by payment locality
Payment localityOfficeFacility
AlabamaUnavailable$987.71
AlaskaUnavailable$1,391.04
ArizonaUnavailable$1,038.34
ArkansasUnavailable$978.95
Atlanta, GAUnavailable$1,084.16
Austin, TXUnavailable$1,065.23
Bakersfield, CAUnavailable$1,061.60
Baltimore area, MDUnavailable$1,111.27
Beaumont, TXUnavailable$1,029.99
Brazoria, TXUnavailable$1,042.67

50225 rates by state

Office rate range in each state. Select a state to see its payment localities.

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Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

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50225 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

How the 50225 rate is calculated

Each of 50225’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 50225

RVUs × geographic indexes × conversion factor

Office or facility?

Work21.33

21.33 RVUs× 1.000 GPCI

Practice expense7.64

7.64 RVUs× 1.000 GPCI

Malpractice2.75

2.75 RVUs× 1.000 GPCI

Adjusted RVUs

31.7200

Conversion factor

$33.4009

Medicare rate

$1,059.48

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 50225

50225 has a 90-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 50225

Nephrectomy, complicated removal

RuleCMS valueWhat it means
Global period090Major surgery: the day before, the day of, and 90 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)1Bilateral with modifier 50 pays 150% of the fee schedule amount.
Assistant at surgery (80/81/82/AS)2Paid.
Co-surgeons (62)1Permitted with supporting documentation.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.08/0.83/0.09Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 50225

Nephrectomy, complicated removal

90-day global period ends

Dec 30, 2026

Covers Sep 30, 2026 through Dec 30, 2026 (92 days, including the day before surgery).

Visit on Oct 31, 2026

Day 30 of the 90-day post-op period: related follow-up care is included in the surgical payment.

  • 24Unrelated E/M visit by the same physician
  • 79Unrelated procedure (starts its own global period)
  • 58Staged, more extensive, or therapy procedure that was planned
  • 78Unplanned return to the operating room for a related complication
SurgeryVisit
Sep 23, 2026Jan 10, 2027

Pre-op dayGlobal period

What modifiers do to the payment

Modifier 50 · payment effect

With and without the modifier

50225 without 50 · national facility

$1,059.48

Nephrectomy, complicated removal

50225-50 · Bilateral: 150%

$1,589.22

Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).

When to use modifier 50

50225 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • 50225

    Nephrectomy, complicated removal21.33 wRVU

    Not priced

  • 50220

    Kidney removal, open, nonradical removal18.21 wRVU

    Not priced

  • 50230

    Radical nephrectomy, open, with regional or caval work23.21 wRVU

    Not priced

  • 50234

    Kidney and ureter removal, same-incision bladder cuff23.45 wRVU

    Not priced

  • 50240

    Kidney surgery, open partial resection23.6 wRVU

    Not priced

How to choose

50220Kidney removalOpen, nonradical removal
50220 describes nephrectomy without the complicating circumstances specified for 50225. Choose 50225 when prior surgery, radiotherapy, or infection makes the operation complex and the operative report supports that distinction.
50230Radical nephrectomyOpen, with regional or caval work
50230 describes radical nephrectomy with regional lymphadenectomy. It is selected for that operative extent, rather than for complexity alone.
50234Kidney and ureter removalSame-incision bladder cuff
50234 is for removal of the kidney and ureter through the same incision. Use 50225 for complex nephrectomy when the operative service is not that more extensive kidney-and-ureter removal.
50240Kidney surgeryOpen partial resection
50240 describes partial nephrectomy, preserving part of the kidney. Code 50225 represents complex removal of the kidney.

50225 billing questions

How does this differ from routine nephrectomy code 50220?

Use 50225 when prior surgery, radiotherapy, or infection complicates the kidney removal. Use 50220 for a nephrectomy without those documented complicating circumstances.

What documentation supports the complex code?

Document the prior surgery, radiotherapy, or infection and describe how it made the nephrectomy more difficult. A diagnosis without an operative explanation may not establish the complexity.

Is partial ureter removal separately reported?

Partial ureter removal performed as part of the nephrectomy is included in the service. A more extensive kidney-and-ureter removal is represented by a different procedure code.

How is bilateral reporting handled?

For a bilateral procedure, report modifier 50; CMS pays the service at 150%.

Can an assistant or co-surgeon be reported?

Assistant-at-surgery payment may be available. Co-surgeon payment requires supporting documentation; CMS does not permit team-surgery payment for this code.

What postoperative care is included?

The 90-day global period includes the day-before preoperative visit and 90 days of related postoperative care.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 50225PPRRVU2026_Oct_nonQPP.csv, line 5,886 (RVU26D)

Open CMS sourceHow we calculate rates

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