CPT code 50593: Renal ablation, percutaneous cryotherapy2026 Medicare rate & RVUs in Mississippi

Percutaneous renal tumor cryoablation treats a kidney tumor by placing probes through the skin and freezing the target under imaging guidance.

CMS RVU26DEffective Oct 1, 2026One payment locality3.9K Medicare services in 2024

In Mississippi, Medicare pays $3,055.37 for 50593 in the office and $379.71 when it’s performed in a hospital or facility.

$3,055.37Office (non-facility)
$379.71Hospital or facility
−12.9%vs the national office rate ($3,506.43)

Check a contract rate as a % of Medicare · 50593 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 50593 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Mississippi
  2. What 50593 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 50593 covers

The physician places one or more cryotherapy probes through the skin into a renal tumor and uses freeze-thaw cycles to destroy the target. Imaging guides probe placement and treatment monitoring as part of the procedure. Urologists and interventional radiologists commonly perform this treatment in a hospital or ambulatory surgery setting for patients with a renal mass selected for percutaneous ablation. A biopsy performed as part of the ablation is included in the service.

Report the code for the percutaneous cryotherapy approach, not for laparoscopic ablation or surgical removal of renal tissue. The operative report should support the treated kidney, tumor target, percutaneous access, cryotherapy, and imaging-guided treatment. The procedure has a 10-day global period, which includes related postoperative visits during that period. For bilateral treatment, modifier 50 is paid at 150%. When multiple procedures are performed in one session, the highest-valued procedure is paid in full and the others at 50%. An assistant at surgery may be paid; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Mississippi compares for 50593

Across 109 of 109 payment localities, the office rate for 50593 runs from $3,041.89 in Arkansas to $4,931.49 in San Benito County, CA. Mississippi pays $3,055.37. The RVUs are the same everywhere; the geographic indexes change the dollars.

50593 in Mississippi vs other payment areas
  1. Mississippi · this page$3,055.37
  2. Los Angeles, CA · California$4,090.56+$1,035.19
  3. Washington, DC area · District of Columbia$4,092.64+$1,037.27
  4. Miami, FL · Florida$3,685.55+$630.18
  5. Chicago, IL · Illinois$3,565.47+$510.10
  6. Manhattan, NY · New York$4,059.57+$1,004.20
  7. Alaska · Alaska$3,843.86+$788.49

Other areas in Mississippi first, then benchmark localities. Bars start at $0.

Every other payment area

50593 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$3,094.47$375.31
ArkansasArkansas$3,041.89$372.44
ArizonaArizona$3,403.11$391.82
Bakersfield, CACalifornia$3,805.32$399.37
Chico, CACalifornia$3,802.42$396.47
El Centro, CACalifornia$3,802.58$396.63
Fresno, CACalifornia$3,802.42$396.47
Hanford, CACalifornia$3,802.42$396.47

50593 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$3,041.89

$4,366.96

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
50593 office rate range by state
State / territoryOffice rate rangeLocalities
AK$3,843.861
AL$3,094.471
AR$3,041.891
AZ$3,403.111
CA$3,802.42–$4,931.4929
CO$3,706.821
CT$3,764.151
DC$4,092.641
DE$3,466.441
FL$3,382.23–$3,685.553
GA$3,168.49–$3,564.642
GU$3,929.471
HI$3,929.471
IA$3,216.531
ID$3,234.871
IL$3,247.16–$3,618.954
IN$3,257.581
KS$3,184.891
KY$3,150.151
LA$3,138.77–$3,322.802
MA$3,673.44–$4,132.772
MD$3,544.94–$4,092.643
ME$3,239.60–$3,466.052
MI$3,233.39–$3,416.702
MN$3,576.471
MO$3,066.01–$3,353.593
MS$3,055.371
MT$3,506.361
NC$3,281.551
ND$3,487.581
NE$3,241.411
NH$3,633.061
NJ$3,814.14–$4,036.482
NM$3,248.411
NV$3,504.311
NY$3,337.73–$4,154.185
OH$3,229.551
OK$3,158.511
OR$3,484.26–$3,856.522
PA$3,243.47–$3,648.362
PR$3,540.991
RI$3,613.611
SC$3,259.571
SD$3,485.361
TN$3,201.861
TX$3,217.48–$3,688.148
UT$3,312.061
VA$3,442.95–$4,092.642
VI$3,540.991
VT$3,458.901
WA$3,671.43–$4,238.182
WI$3,350.681
WV$3,102.811
WY$3,498.181

See 50593 in every payment locality

How the 50593 rate is calculated

Each of 50593’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 50593

RVUs × geographic indexes × conversion factor

Office or facility?

Work8.66

8.66 RVUs× 1.000 GPCI

Practice expense95.37

95.37 RVUs× 1.000 GPCI

Malpractice0.95

0.95 RVUs× 1.000 GPCI

Adjusted RVUs

104.9800

Conversion factor

$33.4009

Medicare rate

$3,506.43

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Mississippi inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

5,954

Code
50593
Physician work
8.66
Practice expense
95.37
Malpractice
0.95

GPCI2026.csv

67

Locality
Mississippi
Physician work
1.000
Practice expense
0.861
Malpractice
0.739
Office calculation for 50593 in Mississippi
ComponentRVULocality factorAdjusted
Physician work8.66× 1.0008.6600
Practice expense95.37× 0.86182.1136
Malpractice0.95× 0.7390.7020
Total RVUs91.4756
Conversion factor× 33.4009

Office rate, Mississippi$3055.37

Office: (8.66 × 1 + 95.37 × 0.861 + 0.95 × 0.739) × $33.4009 = $3055.37

Facility: (8.66 × 1 + 2.33 × 0.861 + 0.95 × 0.739) × $33.4009 = $379.71

Open 50593 in the RVU calculator

Payment rules and modifiers for 50593

50593 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 50593

Renal ablation, percutaneous cryotherapy

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)1Bilateral with modifier 50 pays 150% of the fee schedule amount.
Assistant at surgery (80/81/82/AS)2Paid.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 50593

Renal ablation, percutaneous cryotherapy

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 50 · payment effect

With and without the modifier

50593 without 50 · national office

$3,506.43

Renal ablation, percutaneous cryotherapy

50593-50 · Bilateral: 150%

$5,259.65

Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).

When to use modifier 50

How 50593 has changed in Mississippi

50593 · Office / nonfacility

$3055.37

Effective 2026-10-01

The base rate is $77.19 higher than on 2025-10-01, moving from $2978.18 to $3055.37 (2.6%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $2978.18changed to$3055.37

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 8.88 changed to 8.66
    • Practice expense RVU 96.84 changed to 95.37
    • Malpractice RVU 0.89 changed to 0.95
    • Practice expense GPCI 0.852 changed to 0.861
    • Malpractice GPCI 0.768 changed to 0.739

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $3171.94changed to$2978.18

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 100.59 changed to 96.84
    • Malpractice RVU 0.92 changed to 0.89

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $3120.17changed to$3171.94

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $3331.80changed to$3120.17

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 104.84 changed to 100.59
    • Malpractice RVU 0.89 changed to 0.92
    • Practice expense GPCI 0.847 changed to 0.852
    • Malpractice GPCI 0.720 changed to 0.768
  5. January 1, 2023

    RVU23A

    $3490.37changed to$3331.80

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 108.61 changed to 104.84
    • Malpractice RVU 0.79 changed to 0.89
    • Practice expense GPCI 0.842 changed to 0.847
    • Malpractice GPCI 0.671 changed to 0.720

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $3760.64changed to$3490.37

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 116.84 changed to 108.61
    • Malpractice RVU 0.77 changed to 0.79

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $3845.98changed to$3760.64

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 113.64 changed to 116.84
    • Malpractice RVU 0.79 changed to 0.77
    • Practice expense GPCI 0.856 changed to 0.842
    • Malpractice GPCI 0.521 changed to 0.671

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $3962.16changed to$3845.98

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 115.83 changed to 113.64
    • Malpractice RVU 0.78 changed to 0.79
    • Practice expense GPCI 0.870 changed to 0.856
    • Malpractice GPCI 0.370 changed to 0.521

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $4056.16changed to$3962.16

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 118.97 changed to 115.83

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $4025.56changed to$4056.16

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 118.69 changed to 118.97
    • Practice expense GPCI 0.867 changed to 0.870
    • Malpractice GPCI 0.492 changed to 0.370

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $4115.86changed to$4025.56

    • Conversion factor 35.8043 changed to 35.8887
    • Work RVU 9.13 changed to 8.88
    • Practice expense RVU 121.90 changed to 118.69
    • Malpractice RVU 0.82 changed to 0.78
    • Practice expense GPCI 0.864 changed to 0.867
    • Malpractice GPCI 0.613 changed to 0.492

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $4124.22changed to$4115.86

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 121.62 changed to 121.90
    • Malpractice RVU 0.92 changed to 0.82

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $4103.70changed to$4124.22

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $4044.58changed to$4103.70

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 119.32 changed to 121.62
    • Malpractice RVU 0.82 changed to 0.92
    • Practice expense GPCI 0.865 changed to 0.864
    • Malpractice GPCI 0.687 changed to 0.613

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $4158.79changed to$4044.58

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 129.85 changed to 119.32
    • Malpractice RVU 0.86 changed to 0.82
    • Practice expense GPCI 0.866 changed to 0.865
    • Malpractice GPCI 0.761 changed to 0.687

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $4158.79

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$3,055.37$379.71RVU26D
2026-07-01$3,055.37$379.71RVU26C
2026-04-01$3,055.37$379.71RVU26B
2026-01-01$3,055.37$379.71RVU26A
2025-10-01$2,978.18$412.42RVU25D
2025-07-01$2,978.18$412.42RVU25C
2025-04-01$2,978.18$412.42RVU25B
2025-01-01$2,978.18$412.42RVU25A
2024-10-01$3,171.94$420.93RVU24D
2024-07-01$3,171.94$420.93RVU24C
2024-04-01$3,171.94$420.93RVU24B
2024-03-09$3,171.94$420.93RVU24AR
2024-01-01$3,120.17$414.06RVU24A
2023-10-01$3,331.80$426.82RVU23D
2023-07-01$3,331.80$426.82RVU23C
2023-04-01$3,331.80$426.82RVU23B
2023-01-01$3,331.80$426.82RVU23A
2022-10-01$3,490.37$429.38RVU22D
2022-07-01$3,490.37$429.38RVU22C
2022-04-01$3,490.37$429.38RVU22B
2022-01-01$3,490.37$429.38RVU22A
2021-10-01$3,760.64$433.06RVU21D
2021-07-01$3,760.64$433.06RVU21C
2021-04-01$3,760.64$433.06RVU21B
2021-01-01$3,760.64$433.06RVU21A
2020-10-01$3,845.98$447.78RVU20D
2020-07-01$3,845.98$447.78RVU20C
2020-04-01$3,845.98$447.78RVU20B
2020-01-01$3,845.98$447.78RVU20A
2019-10-01$3,962.16$445.81RVU19D
2019-07-01$3,962.16$445.81RVU19C
2019-04-01$3,962.16$445.81RVU19B
2019-01-01$3,962.16$445.81RVU19A
2018-10-01$4,056.16$446.26RVU18D
2018-07-01$4,056.16$446.26RVU18C
2018-04-01$4,056.16$446.26RVU18B
2018-01-01$4,056.16$446.26RVU18AR1
2017-10-01$4,025.56$451.01RVU17D
2017-07-01$4,025.56$451.01RVU17C
2017-04-01$4,025.56$451.01RVU17B
2017-01-01$4,025.56$451.01RVU17A
2016-10-01$4,115.86$466.16RVU16D
2016-07-01$4,115.86$466.16RVU16C
2016-04-01$4,115.86$466.16RVU16B
2016-01-01$4,115.86$466.16RVU16A
2015-10-01$4,124.22$470.35RVU15D
2015-07-01$4,124.22$470.35RVU15C
2015-04-01$4,103.70$468.01RVU15B
2015-01-01$4,103.70$468.01RVU15A
2014-10-01$4,044.58$468.71RVU14D
2014-07-01$4,044.58$468.71RVU14C
2014-04-01$4,044.58$468.71RVU14B
2014-01-01$4,044.58$468.71RVU14A
2013-10-01$4,158.79$453.99RVU13D
2013-07-01$4,158.79$453.99RVU13C
2013-04-01$4,158.79$453.99RVU13B
2013-01-01$4,158.79$453.99RVU13AR

Price 50593 for an earlier date of service

Where the Mississippi rate applies

Mississippi is a Medicare payment area, not a city. Our Census mapping connects it to 427 cities and communities in Mississippi. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Aberdeen
  • Ackerman
  • Agricola
  • Alcorn State University
  • Algoma
  • Alligator
  • Amory

Browse all communities in Mississippi

50593 billing questions

How does this differ from 50592?

Both describe percutaneous renal tumor ablation with imaging guidance. Report 50593 for cryotherapy and 50592 for radiofrequency ablation.

Can the biopsy be billed separately?

A biopsy performed as part of the ablation is included. The documentation should describe the biopsy if performed, but it is not a separate service within this procedure.

How is this different from 50542?

50593 is performed percutaneously with cryotherapy. Code 50542 describes laparoscopic ablation of a renal mass.

What documentation supports reporting this code?

Document the renal tumor and side, percutaneous probe placement, use of cryotherapy, and imaging-guided treatment. Include biopsy details when a biopsy is performed.

How are bilateral procedures and other same-session procedures handled?

For bilateral treatment, modifier 50 is paid at 150%. Under the multiple procedure reduction, the highest-valued procedure is paid in full and other procedures in the same session at 50%.

Are assistant surgeons or co-surgeons allowed?

An assistant at surgery may be paid. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 50593PPRRVU2026_Oct_nonQPP.csv, line 5,954 (RVU26D)
Geographic factors for MississippiGPCI2026.csv, line 67 (RVU26D)

Open CMS sourceHow we calculate rates

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