CPT code 51720: Bladder instillation, antineoplastic agent2026 Medicare rate & RVUs

Report this service when a clinician delivers an antineoplastic agent into the bladder through a catheter for intravesical treatment, such as BCG therapy.

CMS RVU26DEffective Oct 1, 2026109 payment localities159.2K Medicare services in 2024

Medicare pays $91.85 for 51720 nationally in the office and $38.08 in a hospital or facility. Local office rates run $81.64–$119.70.

Medicare rate · 51720

Bladder instillation, antineoplastic agent

Office or facility?

Work RVUs
0.85
Total RVUs
2.75
Global days
000

National rate · 2026

$91.85

Office setting, before claim adjustments.

See every locality for 51720 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 51720 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 51720 covers

A urologist or other qualified clinician places a catheter and delivers an antineoplastic agent into the bladder, commonly in an office or outpatient setting. Intravesical BCG and chemotherapy are typical treatments for bladder cancer, including treatment after tumor resection or for carcinoma in situ. The service covers the drug’s delivery and retention in the bladder; it is distinct from endoscopic biopsy, lesion destruction, or simple bladder irrigation.

Select 51720 for the therapeutic instillation, not for catheter placement alone. Document the agent and administration details, including the retention instructions when available. The drug may be reported separately with the applicable drug code; catheter placement integral to the instillation is not separately reported as 51701. The 0-day global includes same-day preoperative and postoperative care. When multiple procedures occur in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this service, and co-surgeon and team-surgery billing are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 51720 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$81.64 to $119.70

$81.64$100.67$119.70
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

51720 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$82.78$35.73
Alaska$108.28$51.01
Arizona$89.47$37.36
Arkansas$81.64$35.45
Atlanta, GA$93.63$39.00
Austin, TX$94.96$38.06
Bakersfield, CA$96.69$37.76
Baltimore area, MD$97.54$39.84
Beaumont, TX$86.21$37.28
Brazoria, TX$90.73$37.44

51720 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$81.64

$108.28

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
51720 office rate range by state
State / territoryOffice rate rangeLocalities
AK$108.281
AL$82.781
AR$81.641
AZ$89.471
CA$96.37–$119.7029
CO$95.211
CT$97.801
DC$104.441
DE$90.911
FL$91.07–$99.923
GA$86.10–$93.632
GU$98.501
HI$98.501
IA$84.561
ID$85.131
IL$88.72–$97.114
IN$85.601
KS$84.291
KY$84.901
LA$84.82–$88.822
MA$94.73–$104.212
MD$92.55–$104.443
ME$85.68–$89.962
MI$87.12–$92.282
MN$91.001
MO$83.51–$88.993
MS$82.581
MT$91.851
NC$86.521
ND$89.671
NE$84.961
NH$93.841
NJ$98.84–$103.462
NM$87.631
NV$91.301
NY$87.77–$108.125
OH$86.681
OK$84.641
OR$90.52–$98.002
PA$86.75–$95.522
PR$92.461
RI$93.971
SC$86.761
SD$89.411
TN$84.711
TX$86.21–$94.968
UT$87.891
VA$89.76–$104.442
VI$92.461
VT$89.441
WA$94.51–$106.172
WI$86.801
WV$85.601
WY$90.901

How the 51720 rate is calculated

Each of 51720’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 51720

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.85

0.85 RVUs× 1.000 GPCI

Practice expense1.79

1.79 RVUs× 1.000 GPCI

Malpractice0.11

0.11 RVUs× 1.000 GPCI

Adjusted RVUs

2.7500

Conversion factor

$33.4009

Medicare rate

$91.85

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 51720

The CMS indicators that decide how 51720 is paid alongside other services.

CMS payment indicators · 51720

Bladder instillation, antineoplastic agent

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

51720 without 51 · national office

$91.85

Bladder instillation, antineoplastic agent

51720-51 · Second procedure: 50%

$45.93

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

51720 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 51720

    Bladder instillation, antineoplastic agent0.85 wRVU

    $91.85

  • 51700

    Bladder irrigation, simple lavage or instillation0.59 wRVU

    $78.16−$13.69

  • 51701

    Bladder catheterization, in-and-out catheter0.49 wRVU

    $45.43−$46.42

  • 52224

    Bladder lesion treatment, lesions under 0.5 cm3.95 wRVU

    $760.20+$668.35

How to choose

51700Bladder irrigationSimple lavage or instillation
51700 is bladder irrigation. Use 51720 when an antineoplastic agent is delivered for therapeutic intravesical treatment, rather than when the bladder is simply irrigated.
51701Bladder catheterizationIn-and-out catheter
51701 reports catheter insertion without the therapeutic bladder instillation. Catheter placement integral to the 51720 service is not separately reported as 51701.
52224Bladder lesion treatmentLesions under 0.5 cm
52224 is an endoscopic procedure to treat a small bladder lesion. 51720 is used for delivery of an intravesical antineoplastic agent, not endoscopic lesion treatment.

51720 billing questions

How is 51720 different from bladder irrigation or catheter insertion?

51720 represents therapeutic delivery of an antineoplastic agent into the bladder. Irrigation alone or catheter placement without that treatment does not meet the service; do not separately report 51701 for catheter placement integral to the instillation.

Can the drug be billed separately?

The drug may be reported separately with its applicable HCPCS drug code when the drug was supplied and billing requirements are met. 51720 represents the instillation service.

Should modifier 50 be appended for treatment of both sides?

No. Modifier 50 is inappropriate for this bladder service.

How does Medicare handle 51720 with another procedure in the same session?

The highest-valued procedure is paid in full, and other procedures in that session are subject to the standard multiple-procedure reduction. Same-day preoperative and postoperative care is included in the 0-day global period.

Can an assistant or co-surgeon be reported?

Medicare does not pay an assistant at surgery for 51720. Co-surgeon and team-surgery billing are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 51720PPRRVU2026_Oct_nonQPP.csv, line 6,052 (RVU26D)

Open CMS sourceHow we calculate rates

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