CPT code 57421: Colposcopy, entire vagina with biopsy2026 Medicare rate & RVUs in Alabama

In Alabama, Medicare pays $163.92 for 57421 in the office and $100.21 when it’s performed in a hospital or facility.

Check a contract rate as a % of Medicare · 57421 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 57421 covers

A clinician uses a colposcope to inspect the entire vaginal canal and, when present, the cervix, then takes directed tissue samples from abnormal areas. Gynecologists commonly perform this in an office or outpatient facility when evaluating abnormal vaginal cytology, suspected vaginal intraepithelial lesions, or visible lesions requiring histologic assessment, including in patients who have had a hysterectomy.

Report the service when the examination covers the entire vagina and includes biopsy; the code accounts for the colposcopic examination and biopsy work. The record should identify the examined anatomy, the abnormal area sampled, and the clinical reason for sampling. CMS assigns a 0-day global period, so same-day preoperative and postoperative care is included. For multiple procedures in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this service, and co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Alabama compares for 57421

Across 109 of 109 payment localities, the office rate for 57421 runs from $161.67 in Arkansas to $225.94 in San Benito County, CA. Alabama pays $163.92. The RVUs are the same everywhere; the geographic indexes change the dollars.

Every other payment area

57421 rates by state

Office rate range in each state. Select a state to see its payment localities.

See 57421 in every payment locality

How the 57421 rate is calculated

Each of 57421’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 57421

The CMS indicators that decide how 57421 is paid alongside other services.

What modifiers do to the payment

When to use modifier 51

Codes related to 57421

Related codes aren’t interchangeable: bill the code that matches the service performed.

How 57421 has changed in Alabama

Price 57421 for an earlier date of service

Where the Alabama rate applies

Alabama is a Medicare payment area, not a city. Our Census mapping connects it to 595 cities and communities in Alabama. Some span more than one payment area; confirm with the service ZIP.

• Abanda
• Abbeville
• Adamsville
• Addison
• Akron
• Alabaster
• Albertville
• Alexander City

Browse all communities in Alabama

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates