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CPT code 57500: Cervical biopsy, tissue sampling or lesion excision2026 Medicare rate & RVUs in North Carolina

Reports tissue sampling or local excision of a cervical lesion, commonly performed for evaluation of an abnormal screening result or visible cervical finding.

CMS RVU26DEffective Oct 1, 2026One payment locality6.1K Medicare services in 2024

In North Carolina, Medicare pays $141.72 for 57500 in the office and $64.44 when it’s performed in a hospital or facility.

$141.72Office (non-facility)
$64.44Hospital or facility
−6.3%vs the national office rate ($151.31)

Check a contract rate as a % of Medicare · 57500 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 57500 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in North Carolina
  2. What 57500 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 57500 covers

A gynecologist or other qualified clinician removes cervical tissue for examination, often after an abnormal Pap or HPV result or when a visible cervical lesion needs evaluation. The service may involve one or multiple samples from the cervix, or local removal of a lesion; it is commonly performed in an office using a speculum and biopsy instrument. The tissue is submitted for pathology. Sampling from the endocervical canal with a curette is a different service.

Report 57500 for the cervical tissue biopsy or local lesion excision, documenting the site and procedure performed. One reporting covers single or multiple cervical biopsy samples in the same service. A 0-day global period includes same-day preoperative and postoperative care. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and the others at 50%. Modifier 50 is inappropriate. Medicare does not pay an assistant at surgery for this service; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How North Carolina compares for 57500

Across 109 of 109 payment localities, the office rate for 57500 runs from $133.07 in Arkansas to $198.85 in San Benito County, CA. North Carolina pays $141.72. The RVUs are the same everywhere; the geographic indexes change the dollars.

57500 in North Carolina vs other payment areas
  1. North Carolina · this page$141.72
  2. Los Angeles, CA · California$169.81+$28.09
  3. Washington, DC area · District of Columbia$172.94+$31.22
  4. Miami, FL · Florida$166.34+$24.62
  5. Chicago, IL · Illinois$161.19+$19.47
  6. Manhattan, NY · New York$174.96+$33.24
  7. Alaska · Alaska$174.54+$32.82

Other areas in North Carolina first, then benchmark localities. Bars start at $0.

Every other payment area

57500 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$135.11$62.63
ArkansasArkansas$133.07$61.91
ArizonaArizona$147.03$66.77
Bakersfield, CACalifornia$159.41$68.62
Chico, CACalifornia$158.82$68.03
El Centro, CACalifornia$158.85$68.07
Fresno, CACalifornia$158.82$68.03
Hanford, CACalifornia$158.82$68.03

57500 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$133.07

$178.83

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
57500 office rate range by state
State / territoryOffice rate rangeLocalities
AK$174.541
AL$135.111
AR$133.071
AZ$147.031
CA$158.82–$198.8529
CO$156.971
CT$161.661
DC$172.941
DE$149.531
FL$150.20–$166.343
GA$141.29–$154.522
GU$162.771
HI$162.771
IA$138.131
ID$139.191
IL$146.10–$161.194
IN$140.021
KS$137.731
KY$139.031
LA$138.91–$146.052
MA$156.08–$172.552
MD$152.38–$172.943
ME$140.24–$147.772
MI$143.06–$152.442
MN$149.421
MO$136.60–$146.273
MS$134.851
MT$151.291
NC$141.721
ND$147.141
NE$138.841
NH$154.741
NJ$163.23–$171.082
NM$143.981
NV$150.241
NY$143.96–$179.705
OH$142.211
OK$138.481
OR$148.80–$161.812
PA$142.29–$157.682
PR$152.361
RI$154.761
SC$142.261
SD$146.651
TN$138.481
TX$141.34–$156.698
UT$144.281
VA$147.46–$172.942
VI$152.361
VT$146.791
WA$155.71–$175.862
WI$142.031
WV$140.551
WY$149.481

See 57500 in every payment locality

How the 57500 rate is calculated

Each of 57500’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 57500

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.17

1.17 RVUs× 1.000 GPCI

Practice expense3.15

3.15 RVUs× 1.000 GPCI

Malpractice0.21

0.21 RVUs× 1.000 GPCI

Adjusted RVUs

4.5300

Conversion factor

$33.4009

Medicare rate

$151.31

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact North Carolina inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

6,498

Code
57500
Physician work
1.17
Practice expense
3.15
Malpractice
0.21

GPCI2026.csv

83

Locality
North Carolina
Physician work
1.000
Practice expense
0.933
Malpractice
0.639
Office calculation for 57500 in North Carolina
ComponentRVULocality factorAdjusted
Physician work1.17× 1.0001.1700
Practice expense3.15× 0.9332.9390
Malpractice0.21× 0.6390.1342
Total RVUs4.2431
Conversion factor× 33.4009

Office rate, North Carolina$141.72

Office: (1.17 × 1 + 3.15 × 0.933 + 0.21 × 0.639) × $33.4009 = $141.72

Facility: (1.17 × 1 + 0.67 × 0.933 + 0.21 × 0.639) × $33.4009 = $64.44

Open 57500 in the RVU calculator

Payment rules and modifiers for 57500

The CMS indicators that decide how 57500 is paid alongside other services.

CMS payment indicators · 57500

Cervical biopsy, tissue sampling or lesion excision

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

57500 without 51 · national office

$151.31

Cervical biopsy, tissue sampling or lesion excision

57500-51 · Second procedure: 50%

$75.66

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

Codes related to 57500

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 57500
CodeHow it relatesOffice range, North Carolina
Often billed with
57505Cervical sampling, endocervical canalMay be reported for separately performed endocervical canal sampling in the same encounter.$139.52
Used instead
57455Cervical biopsy, colposcopy-guided biopsyIncludes colposcopy with cervical biopsy; use when the biopsy is part of that colposcopy service.$151.01
57520Cervical cone, non-loop excisionCervical conization is a more extensive excisional approach than a local biopsy or lesion excision.$337.47
57510Cervical cautery, noncryo, nonlaser methodCervical cauterization treats tissue rather than obtaining a biopsy specimen.$153.50

How 57500 has changed in North Carolina

57500 · Office / nonfacility

$141.72

Effective 2026-10-01

The base rate is $5.15 higher than on 2025-10-01, moving from $136.57 to $141.72 (3.8%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $136.57changed to$141.72

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.20 changed to 1.17
    • Practice expense RVU 3.12 changed to 3.15
    • Malpractice RVU 0.20 changed to 0.21
    • Practice expense GPCI 0.926 changed to 0.933
    • Malpractice GPCI 0.665 changed to 0.639

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $143.93changed to$136.57

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 3.23 changed to 3.12

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $141.59changed to$143.93

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $147.85changed to$141.59

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 3.26 changed to 3.23
    • Malpractice RVU 0.19 changed to 0.20
    • Practice expense GPCI 0.927 changed to 0.926
    • Malpractice GPCI 0.742 changed to 0.665

  5. January 1, 2023

    RVU23A

    $153.17changed to$147.85

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 3.30 changed to 3.26
    • Malpractice RVU 0.20 changed to 0.19
    • Practice expense GPCI 0.928 changed to 0.927
    • Malpractice GPCI 0.819 changed to 0.742

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $149.59changed to$153.17

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 3.15 changed to 3.30

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $139.79changed to$149.59

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 2.72 changed to 3.15
    • Malpractice RVU 0.19 changed to 0.20
    • Practice expense GPCI 0.930 changed to 0.928
    • Malpractice GPCI 0.757 changed to 0.819

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $129.21changed to$139.79

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 2.45 changed to 2.72
    • Malpractice RVU 0.15 changed to 0.19
    • Practice expense GPCI 0.931 changed to 0.930
    • Malpractice GPCI 0.695 changed to 0.757

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $122.70changed to$129.21

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 2.26 changed to 2.45

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $122.85changed to$122.70

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 2.27 changed to 2.26
    • Malpractice GPCI 0.732 changed to 0.695

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $122.34changed to$122.85

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 2.26 changed to 2.27
    • Practice expense GPCI 0.930 changed to 0.931
    • Malpractice GPCI 0.768 changed to 0.732

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $123.39changed to$122.34

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 2.27 changed to 2.26
    • Malpractice RVU 0.16 changed to 0.15

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $122.78changed to$123.39

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $122.52changed to$122.78

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 2.24 changed to 2.27
    • Malpractice RVU 0.19 changed to 0.16
    • Practice expense GPCI 0.929 changed to 0.930
    • Malpractice GPCI 0.732 changed to 0.768

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $123.77changed to$122.52

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 2.48 changed to 2.24
    • Malpractice RVU 0.20 changed to 0.19
    • Practice expense GPCI 0.927 changed to 0.929
    • Malpractice GPCI 0.695 changed to 0.732

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $123.77

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$141.72$64.44RVU26D
2026-07-01$141.72$64.44RVU26C
2026-04-01$141.72$64.44RVU26B
2026-01-01$141.72$64.44RVU26A
2025-10-01$136.57$69.18RVU25D
2025-07-01$136.57$69.18RVU25C
2025-04-01$136.57$69.18RVU25B
2025-01-01$136.57$69.18RVU25A
2024-10-01$143.93$70.88RVU24D
2024-07-01$143.93$70.88RVU24C
2024-04-01$143.93$70.88RVU24B
2024-03-09$143.93$70.88RVU24AR
2024-01-01$141.59$69.72RVU24A
2023-10-01$147.85$71.83RVU23D
2023-07-01$147.85$71.83RVU23C
2023-04-01$147.85$71.83RVU23B
2023-01-01$147.85$71.83RVU23A
2022-10-01$153.17$73.21RVU22D
2022-07-01$153.17$73.21RVU22C
2022-04-01$153.17$73.21RVU22B
2022-01-01$153.17$73.21RVU22A
2021-10-01$149.59$73.49RVU21D
2021-07-01$149.59$73.49RVU21C
2021-04-01$149.59$73.49RVU21B
2021-01-01$149.59$73.49RVU21A
2020-10-01$139.79$74.68RVU20D
2020-07-01$139.79$74.68RVU20C
2020-04-01$139.79$74.68RVU20B
2020-01-01$139.79$74.68RVU20A
2019-10-01$129.21$73.17RVU19D
2019-07-01$129.21$73.17RVU19C
2019-04-01$129.21$73.17RVU19B
2019-01-01$129.21$73.17RVU19A
2018-10-01$122.70$73.76RVU18D
2018-07-01$122.70$73.76RVU18C
2018-04-01$122.70$73.76RVU18B
2018-01-01$122.70$73.76RVU18AR1
2017-10-01$122.85$74.41RVU17D
2017-07-01$122.85$74.41RVU17C
2017-04-01$122.85$74.41RVU17B
2017-01-01$122.85$74.41RVU17A
2016-10-01$122.34$74.06RVU16D
2016-07-01$122.34$74.06RVU16C
2016-04-01$122.34$74.06RVU16B
2016-01-01$122.34$74.06RVU16A
2015-10-01$123.39$74.60RVU15D
2015-07-01$123.39$74.60RVU15C
2015-04-01$122.78$74.23RVU15B
2015-01-01$122.78$74.23RVU15A
2014-10-01$122.52$74.93RVU14D
2014-07-01$122.52$74.93RVU14C
2014-04-01$122.52$74.93RVU14B
2014-01-01$122.52$74.93RVU14A
2013-10-01$123.77$73.31RVU13D
2013-07-01$123.77$73.31RVU13C
2013-04-01$123.77$73.31RVU13B
2013-01-01$123.77$73.31RVU13AR

Price 57500 for an earlier date of service

Where the North Carolina rate applies

North Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 785 cities and communities in North Carolina. Some span more than one payment area; confirm with the service ZIP.

  • Aberdeen
  • Advance
  • Ahoskie
  • Alamance
  • Albemarle
  • Alexis
  • Alliance
  • Altamahaw

Browse all communities in North Carolina

57500 billing questions

How does 57500 differ from endocervical curettage?

57500 reports tissue biopsy or local lesion excision from the cervix. Use 57505 for curettage sampling of the endocervical canal.

Can 57500 be reported with a colposcopy code?

When the colposcopy service includes cervical biopsy, such as 57455, do not separately report 57500 for that same biopsy.

How many units are reported for multiple cervical samples?

Report 57500 once for single or multiple cervical biopsy samples performed in the same service.

Is modifier 50 appropriate for biopsies from both sides of the cervix?

No. CMS identifies bilateral adjustment as inappropriate for this code; report the service without modifier 50.

What documentation supports 57500?

Document the cervical site sampled or lesion removed and the procedure performed. Pathology submission supports that tissue was obtained for examination.

How does the 0-day global period affect same-day care?

Same-day preoperative and postoperative care is included in the procedure. The global period is 0 days.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 57500PPRRVU2026_Oct_nonQPP.csv, line 6,498 (RVU26D)
Geographic factors for North CarolinaGPCI2026.csv, line 83 (RVU26D)

Open CMS sourceHow we calculate rates

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